Summary list of publications:

HIGHLY ACCESSED PUBLICATIONS:

Robinson, J.C., Wilmot, J.H., Hasselmo, M.E. (2023) Septo-hippocampal dynamics and the encoding of space and time. Trends Neurosci. 46(9):712-725. PMCID10538955 PDF

Alexander AS, Carstensen LC, Hinman JR, Raudies F, Chapman GW, Hasselmo ME (2020) Egocentric boundary vector tuning of the retrosplenial cortex. Science Advances, 6: eaaz2322. PMCID: PMC7035004 PDF

Hinman JR, Chapman GW, Hasselmo ME. (2019) Neuronal representation of environmental boundaries in egocentric coordinates. Nature Communications 10(1):2772. PMCID: PMC6591168. PDF

Brandon, M.P., Bogaard, A.R., Libby, C.P., Connerney, M.A., Gupta, K., Hasselmo, M.E. (2011) Reduction of theta rhythm dissociates grid cell spatial periodicity from directional tuning. Science, 332: 595-599. PDF ...Abstract ...Full text

Giocomo LM, Zilli EA, Fransen E, Hasselmo ME. (2007) Temporal frequency of subthreshold oscillations scales with entorhinal grid cell field spacing. Science, 315(5819):1719-22. PDF ...Abstract ...Full text

Hasselmo, M.E. (2006) The role of acetylcholine in learning and memory. Curr. Opinion Neurobiol. 16(6): 710-715. PDF

Hasselmo, M.E., Bodelon, C. and Wyble, B.P. (2002) A proposed function for hippocampal theta rhythm: Separate phases of encoding and retrieval enhance reversal of prior learning. Neural Computation, 14(4): 793-817. PDF

Hasselmo, M.E. (1999) Neuromodulation: Acetylcholine and memory consolidation. Trends in Cognitive Sciences 3: 351-359. PDF

BOOK:

Hasselmo, M.E. (2012) How We Remember: Brain Mechanisms of Episodic Memory. MIT Press: Cambridge, MA. Description.

PEER REVIEWED JOURNAL ARTICLES LISTED BY YEAR:

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2023

Robinson, J.C., Wilmot, J.H., Hasselmo, M.E. (2023) Septo-hippocampal dynamics and the encoding of space and time. Trends Neurosci. 46(9):712-725. PMCID10538955 PDF

Alexander, A.S., Robinson, J.C., Stern, C.E., Hasselmo, M.E. (2023) Gated transformations from egocentric to allocentric reference frames involving retrosplenial cortex, entorhinal cortex and hippocampus. Hippocampus, 33(5):465-487. PDF

Lian, Y., Williams, S., Alexander, A.S., Hasselmo, M.E., Burkitt, A.N. (2023) Learning the vector coding of egocentric boundary cells from visual data. J. Neurosci. 43(28): 5180-5190. PMCID10342228. PDF

Chapman GW, Hasselmo ME. (2023) Predictive learning by a burst-dependent learning rule. Neurobiol Learn Mem. 205:107826. PDF

Lowet E, Sheehan DJ, Chialva U, De Oliveira Pena R, Mount RA, Xiao S, Zhou SL, Tseng HA, Gritton H, Shroff S, Kondabolu K, Cheung C, Wang Y, Piatkevich KD, Boyden ES, Mertz J, Hasselmo ME, Rotstein HG, Han X (2023) Theta and gamma rhythmic coding through two spike output modes in the hippocampus during spatial navigation. Cell Rep. 42(8):112906. PMCID10530698. PDF

Wilmerding, Lucius K., Kondratyev, I., Ramirez, S., Hasselmo, M.E. (2023) Route-dependent spatial engram tagging in mouse dentate gyrus. Neurobiol. Learn Mem. 200:107738. Doi: 10.1016/j.nlm.2023.107738. PMCID: PMC10106405. PDF

Patel M, Gu Y, Carstensen LC, Hasselmo ME, Betke M (2023) Animal pose tracking: 3D multimodal dataset and token-based pose optimization. International Journal of Computer Vision 131: 514-530. PDF

2022

Ning W, Bladon JH, Hasselmo ME (2022) Complementary representations of time in the prefrontal cortex and hippocampus. Hippocampus 32(8): 577-596. PMCID: PMC9444055. PDF

Kopsick JD, Hartzell K, Lazaro H, Nambiar P, Hasselmo ME, Dannenberg H. (2022) Temporal dynamics of cholinergic activity in the septo-hippocampal system. Front Neural Circuits 16: 957441. PMCID: PMC9452968. PDF

Alexander AS, Tung JC, Chapman GW, Conner, AM Shelley LE, Hasselmo ME, Nitz DA (2022) Adaptive integration of self-motion and goals in posterior parietal cortex. Cell Reports 38(10): 110504. PMCID: PMC9026715 PDF

Wilmerding LK, Yazdanbakhsh A, Hasselmo ME (2022) Impact of optogenetic pulse design on CA3 learning and replay: A neural model. Cell Reports Methods 2: 100208 PDF

2021

Carstensen LC, Alexander AS, Chapman GW, Lee AJ, Hasselmo ME (2021) Neural responses in retrosplenial cortex associated with environmental alterations. iScience 24(11):103377. PMCID: PMC8605176. PDF

Levy SJ, Kinsky NR, Mau W, Sullivan DW, Hasselmo ME (2021) Hippocampal spatial memory representations in mice are heterogeneously stable. Hippocampus 31(3): 244-260. PMCID: PMC7983370. PDF

Do Q, Hasselmo ME (2021) Neural circuits and symbolic processing. Neurobiol. Learn Mem. 186: 107552. PDF

Hasselmo ME, Alexander AS, Hoyland A, Robinson JC, Bezaire MJ, Chapman GW, Saudargiene A, Carstensen LC, Dannenberg H. (2021) The Unexplored Territory of Neural Models: Potential Guides for Exploring the Function of Metabotropic Neuromodulation. Neuroscience, 456: 143-158. PMCID: PMC7541517. PDF

2020

Alexander AS, Carstensen LC, Hinman JR, Raudies F, Chapman GW, Hasselmo ME (2020) Egocentric boundary vector tuning of the retrosplenial cortex. Science Advances, 6: eaaz2322. PMCID: PMC7035004 PDF

Kinsky NR, Mau W, Sullivan DW, Levy SJ, Ruesch EA, Hasselmo ME (2020) Trajectory-modulated hippocampal neurons persist throughout memory-guided navigation. Nature Communications, 11(1):2443. PDF

Zhu H, Paschalidis IC, Chang A, Stern CE, Hasselmo ME. (2020) A neural circuit model for a contextual association task inspired by recommender systems. Hippocampus. 30(4):384-395. PDF

Hausler S, Chen Z, Hasselmo ME, Milford M. (2020) Bio-inspired multi-scale fusion. Biol Cybern. 114(2):209-229.

Hasselmo ME, Alexander AS, Dannenberg H, Newman EL. (2020) Overview of computational models of hippocampus and related structures: Introduction to the special issue. Hippocampus. 30(4):295-301.

Issa JB, Tocker G, Hasselmo ME, Heys JG, Dombeck DA. (2020) Navigating Through Time: A Spatial Navigation Perspective on How the Brain May Encode Time. Annu Rev Neurosci. 43: 73-93.

Liu Y, Brincat SL, Miller EK, Hasselmo ME. (2020) A Geometric Characterization of Population Coding in the Prefrontal Cortex and Hippocampus during a Paired-Associate Learning Task. J Cogn Neurosci. 32(8): 1455-1465.

Sherfey JS, Ardid S, Miller EK, Hasselmo ME, Kopell NJ. (2020) Prefrontal oscillations modulate the propagation of neuronal activity required for working memory, Neurobiology of Learning and Memory, 173: 107228. PMCID: PMC7429344.

2019

Hinman JR, Chapman GW, Hasselmo ME. (2019) Neuronal representation of environmental boundaries in egocentric coordinates. Nature Communications 10(1):2772. PMCID: PMC6591168. PDF

Dannenberg H, Kelley C, Hoyland A, Monaghan CK, Hasselmo ME. (2019) The firing rate speed code of entorhinal speed cells differs across behaviorally relevant time scales and does not depend on medial septum inputs. J Neurosci. 39(18):3434-3453. PMCID: PMC6495130. PDF

Liu Y, Tiganj Z, Hasselmo ME, Howard MW. (2019) A neural microcircuit model for a scalable scale-invariant representation of time. Hippocampus. 29(3):260-274 PDF

Dannenberg H, Alexander AS, Robinson JC, Hasselmo ME. (2019) The role of hierarchical dynamical functions in coding for episodic memory and cognition. J Cogn Neurosci. 31(9):1271-1289. PDF

2018

Hinman JR, Dannenberg H, Alexander A, Hasselmo ME. (2018) Neural mechanisms of navigation involving interactions of cortical and subcortical structures. J. Neurophysiol. 119(6):2007-2029. PDF

Hasselmo ME, Stern CE (2018) A network model of behavioural performance in a rule learning task. Phil. Trans. R. Soc. B 373 : 20170275. PMCID: PMC5832697. PDF

Mau W, Sullivan DW, Kinsky NR, Hasselmo ME, Howard MW, Eichenbaum H. (2018) The same hippocampal CA1 population simultaneously codes temporal information over multiple timescales. Curr Biol. 28(10):1499-1508.e4. PMCID: PMC5964012. PDF

Zhu H, Paschalidis IC, Hasselmo ME. (2018) Neural circuits for learning context-dependent associations of stimuli. Neural Networks, 107:48-60. doi: 10.1016/j.neunet.2018.07.018. PDF

Sherfey JS, Ardid S, Hass J, Hasselmo ME, Kopell NJ. (2018) Flexible resonance in prefrontal networks with strong feedback inhibition. PLoS Comput Biol. 14(8):e1006357. doi: 10.1371/journal.pcbi.1006357. PMCID: PMC6103521. PDF

Sherrill KR, Chrastil ER, Aselcioglu I, Hasselmo ME, Stern CE. (2018) Structural Differences in Hippocampal and Entorhinal Gray Matter Volume Support Individual Differences in First Person Navigational Ability. Neuroscience. 380:123-131. doi: 10.1016/j.neuroscience.2018.04.006 PDF

Korotkova T, Ponomarenko A, Monaghan CK, Poulter SL, Cacucci F, Wills T, Hasselmo ME, Lever C. (2018) Reconciling the different faces of hippocampal theta: The role of theta oscillations in cognitive, emotional and innate behaviors. Neurosci. Biobehav. Rev. 85:65-80.

2017

Hasselmo, ME, Hinman, JR, Dannenberg, H, Stern, CE (2017) Models of spatial and temporal dimensions of memory. Curr. Opinion Behav. Sci. 17: 27-33. PMCID: PMC5675108 PDF

Monaghan CK, Chapman GW, Hasselmo ME (2017) Systemic administration of two different anxiolytic drugs decreases local field potential theta frequency in the medial entorhinal cortex without affecting grid cell firing fields. Neuroscience 364: 60-70. PMCID: PMC5786889 PDF

Chrastil ER, Sherrill KR, Aselcioglu I, Hasselmo ME, Stern CE. (2017) Individual differences in human path integration abilities correlate with gray matter volume in retrosplenial cortex, hippocampus, and medial prefrontal cortex. eNeuro. 17;4(2). pii: ENEURO.0346-16.2017. PMCID: PMC5392707. PDF

Ferrante M, Tahvildari B, Duque A, Hadzipasic M, Salkoff D, Zagha EW, Hasselmo ME, McCormick DA. (2016) Distinct Functional Groups Emerge from the Intrinsic Properties of Molecularly Identified Entorhinal Interneurons and Principal Cells. Cerebral Cortex. 27(6):3186-3207. PubMed PMID: 27269961. PDF

Ferrante M, Shay CF, Tsuno Y, Chapman GW, Hasselmo ME. (2016) Post-Inhibitory Rebound Spikes in Rat Medial Entorhinal Layer II/III Principal Cells: In-Vivo, In-Vitro, and Computational Modeling Characterization. Cerebral Cortex. 27(3):2111-2125. PubMed PMID: 26965902. PDF

2016

Hinman JR, Brandon MP, Climer JR, Chapman GW, Hasselmo ME. (2016) Multiple running speed signals in medial entorhinal cortex. Neuron. 91(3):666-79. PMCID: PMC4976037 PDF

Shay CF, Ferrante M, Chapman GW 4th, Hasselmo ME. (2016) Rebound spiking in layer II medial entorhinal cortex stellate cells: Possible mechanism of grid cell function. Neurobiol Learn Mem. 129: 83-98. PMCID: PMC4792788. PDF

Raudies F, Hinman JR, Hasselmo ME. (2016) Modelling effects on grid cells of sensory input during self-motion. Journal of Physiology (London), 594(22):6513-6526. PDF

Heys JG, Shay CF, MacLeod KM, Witter MP, Moss CF, Hasselmo ME. (2016) Physiological properties of neurons in bat entorhinal cortex exhibit an inverse gradient along the dorsal-ventral axis compared to entorhinal neurons in rat. Journal of Neuroscience 36(16):4591-9. PDF

Dannenberg H, Hinman JR, Hasselmo ME (2016) Potential roles of cholinergic modulation in the neural coding of location and movement speed. J. Physiol. Paris 110:52-64. PMCID: PMC5164951 PDF

Chrastil ER, Sherrill KR, Hasselmo ME, & Stern CE. (2016) Which way and how far? Tracking of translation and rotation information for human path integration. Human Brain Mapping, 37(10):3636-55. PDF

2015

Raudies F, Brandon MP, Chapman G,W., Hasselmo ME. (2015) Head direction is coded more strongly than movement direction in a population of entorhinal neurons. Brain Res. 1621:355-67. PMCID: PMC4427560 PDF

Kraus, B.J., Brandon, M.P., Robinson, R.J., Connerney, M.A., Hasselmo, M.E., Eichenbaum, H. (2015) During running in place, grid cells integrate elapsed time and distance run. Neuron, 88(3): 578-589. PMCID: PMC4635558. PDF

Chrastil E.R., Sherrill K.R., Hasselmo M.E., Stern C.E. (2015) There and back again: Hippocampus and retrospenial cortex track homing distance during human path integration. J. Neurosci. 35(46): 15442-52. PDF

Raudies F., Hasselmo M.E. (2015) Differences in visual-spatial input may underlie different compression properties of firing fields for grid cell modules in medial entorhinal cortex. PLoS Comput Biol 11(11): e1004596. PMCID: PMC4652908 PDF

Sherrill KR, Chrastil ER, Ross RS, Erdem UM, Hasselmo ME, Stern CE. (2015) Functional connections between optic flow areas and navigationally responsive brain regions during goal-directed navigation. Neuroimage, 118: 386-96. PDF

Tsuno Y, Chapman GW, Hasselmo ME. (2015) Rebound spiking properties of mouse medial entorhinal cortex neurons in vivo. Eur J Neurosci., 42(11):2974-84. NIHMSID: 759217 PDF

Climer JR, DiTullio R, Newman EL, Hasselmo ME, Eden UT. (2015) Examination of rhythmicity of extracellularly recorded neurons in the entorhinal cortex. Hippocampus. 25(4): 460-473. PMCID: PMC4457388. PDF

Erdem UM, Milford MJ, Hasselmo ME. (2015) A hierarchical model of goal directed navigation selects trajectories in a visual environment. Neurobiol Learn Mem. 117:109-21. PDF

Tiganj Z, Hasselmo ME, Howard MW. (2015) A Simple biophysically plausible model for long time constants in single neurons. Hippocampus. 25(1):27-37. PMCID: PMC4437481. PDF

Chen Z, Lowry S, Jacobson A, Hasselmo ME, Milford M. (2015) Bio-inspired homogeneous multi-scale place recognition. Neural Netw. 72:48-61. PDF

2014

Hasselmo, M.E. Stern, C.E. (2014) Theta rhythm and the encoding and retrieval of space and time. Neuroimage, 85:656-666. NIHMSID: 494525. PDF

Newman, E.L., Climer, J.R., Hasselmo, M.E. (2014) Grid cell spatial tuning reduced following systemic muscarinic receptor blockade. Hippocampus. 24(6): 643-655. PMCID: PMC4028397 PDF

Hasselmo, M.E., Shay, C.F. (2014) Grid cell firing patterns may arise from feedback interaction between intrinsic rebound spiking and transverse traveling waves with multiple heading angles. Frontiers Syst. Neurosci. 8: 201. PMCID: PMC4215619 PDF

Gupta K., Beer, N.J., Keller, L.A., Hasselmo, M.E. (2014) Medial entorhinal grid cells and head direction cells rotate with a Tmaze more often during less recently-experienced rotations. Cerebral Cortex, 24(6): 1630-1644. PMCID: PMC4014184 PDF

Erdem, U.M., Hasselmo, M.E. (2014) A biologically inspired hierarchical goal directed navigation model. J. Physiol. Paris 108(1): 28-37. PMCID: PMC3949664 PDF

Howard, M.W., MacDonald, C.J., Tiganj, Z., Shankar, K.H., Du, Q., Hasselmo, M.E., Eichenbaum, H. (2014) A unified framework for coding time, space, and sequences in the hippocampal region. J Neurosci. 34(13):4692-707. PMCID: PMC3965792 PDF

Onslow, C.E.A., Hasselmo, M.E., Newman, E.L. (2014) DC-shifts in amplitude in-field generated by an oscillatory intereference model of grid cell firing. PLoS One. 9(3):e93250. PMCID: PMC3966868. PDF

Raudies, F., Zilli, E.A., Hasselmo, M.E. (2014) Deep belief networks learn context dependent behavior. PLoS One. 9(3):e93250. PMCID: PMC3966868. PDF

Brown, T.I., Hasselmo, M.E., Stern, C.E. (2014) A high-resolution study of hippocampal and medial temportal lobe correlates of spatial context and prospective overlapping route memory. Hippocampus. 24(7):819-39. PubMed PMID: 24659134. PDF

2013

Hasselmo, M.E. (2013) Neuronal rebound spiking, resonance frequency and theta cycle skipping may contribute to grid cell firing in medial entorhinal cortex. Philosophical Transactions of the Royal Society B. PDF

Heys, J.G., MacLeod, K.M., Moss, C.F., Hasselmo, M.E. (2013) Bat and rat neurons differ in theta frequency resonance despite similar coding of space. Science, 340: 363-367. PDF

Brandon, M.P., Bogaard, A.R., Schultheiss, N.W., Hasselmo, M.E. (2013) Segregation of cortical head direction cell assemblies on alternating theta cycles. Nature Neuroscience, 16(6): 739-748. PMCID: PMC3703458. PDF

Climer, J.R., Newman, E.L., Hasselmo, M.E. (2013) Phase coding by grid cells in unconstrained environments: Twodimensional (2D) phase precession. Eur. J. Neurosci, 38(4):2526-2541. PMCID: PMC3912569. PDF

Gupta K., Beer, N.J., Keller, L.A., Hasselmo, M.E. (2013) Medial entorhinal grid cells and head direction cells rotate with a Tmaze more often during less recently-experienced rotations. Cerebral Cortex, 24(6): 1630-1644. PMCID: PMC4014184. PDF

Tsuno, Y., Schultheiss, N.W., Hasselmo, M.E. (2013) In vivo cholinergic modulation of the cellular properties of medial entorhinal cortex neurons. J. Physiol. (Lond.), 591(10): 2611-2627. PDF

Kraus, B.J., Robinson, R.J., White, J.A., Eichenbaum, H., Hasselmo, M.E. (2013) Hippocampal "Time Cells": Time versus path integration. Neuron, 78(6): 1090-1101. NIHMSID: 484591. PDF

Schon, K., Ross, R.S., Hasselmo, M.E., Stern, C.E. (2013) Complementary roles of medial temporal lobes and mid-dorsolateral prefrontal cortex for working memory for novel and familiar trial-unique visual stimuli. Eur. J. Neurosci. 37(4):668-678. PDF

Hasselmo, M.E. (2013) Location memory: separate cortical coding for distal and local cues. Current Biology 23:16. PDF

Newman, E.L., Gillet, S.N., Climer, J.R., Hasselmo, M.E. (2013) Cholinergic blockade reduces theta-gamma phase amplotude coupling and speed modulation of theta frequency consistent with behavioral effects on encoding. J Neuroscience 33: 19635-19646 PDF

Gupta, K., Erdem, U.M., Hasselmo, M.E. (2013) Modeling of grid cell activity demonstrates in vivo entorhinal 'look-ahead' properties. Neuroscience 247: 395-411. PDF

Yoshida, M., Jochems, A., Hasselmo, M.E. (2013) Comparison of properties of medial entorhinal cortex layer II neurons in two anatomical dimensions with and without cholinergic activation. PLoSONE 8:9. PDF

2012

Heys, J.G. and Hasselmo, M.E. (2012) Neuromodulation of Ih in layer II medial entorhinal cortex stellate cells: a voltage clamp study. Journal of Neuroscience, 32: 9066-9072. PMCID: PMC3462016. PDF

Shay, C.F., Boardman, I.S., James, N.M., Hasselmo, M.E. (2012) Voltage dependence of subthreshold resonance frequency in layer II of medial entorhinal cortex. Hippocampus, 22(8): 1733-49. PMCID: PMC3371298. PDF

Erdem, U.M., Hasselmo, M.E. (2012) A goal-directed spatial navigation model using forward trajectory planning based on grid cells. Eur. J. Neurosci. 35(6):916-931. PMCID: PMC3564559. PDF

Hasselmo, M.E., Brandon, M.P. (2012) A model combining oscillations and attractor dynamics for generation of grid cell firing. Frontiers in Neural Circuits, 6:30. PMCID: PMC3361022. PDF

Gupta, K., Keller, L., Hasselmo, M.E. (2012) Reduced spiking in entorhinal cortex during the delay period of a cued spatial response task. Learning and Memory, 19(6): 219-230. PMCID: PMC3370375. PDF

Newman, E.L., Shay, C.F., Hasselmo, M.E. (2012) Malignant synaptic growth and Alzheimer's disease. Future Neurology 7: 557-571. PMCID: PMC3571723. PDF

Heys, J.G., Schultheiss, N.W., Shay, C.F., Tsuno, Y., Hasselmo, M.E. (2012) Effects of acetylcholine on neuronal properties in entorhinal cortex. Front. Behav. Neurosci. 6:32. PMCID: PMC3402879. PDF

Raudies, F., Hasselmo, M.E. (2012) Modeling boundary vector cell firing given optic flow as a cue. PLoS Computational Biology, 8(6):e1002553. PMCID: PMC3386186. PDF

Barry, C., Heys, J.G., Hasselmo, M.E. (2012) Possible role of acetylcholine in regulating spatial novelty effects on theta rhythm and grid cells. Frontiers in Neural Circuits, 6:5. DOI: 10.3389. PMCID: PMC3282552. PDF

Raudies, F., Mingolla, E., Hasselmo, M.E. (2012) Modeling the influence of optic flow on grid cell firing in the absence of other cues. Journal of Computational Neuroscience, 33: 475-493. DOI: 10.1007/s10827-012-0396-6. PDF

Cutsuridis V, Hasselmo M. (2012) GABAergic contributions to gating, timing, and phase precession of hippocampal neuronal activity during theta oscillations. Hippocampus. 22(7):1597-621. PMID: 22252986. PDF

Newman E.L., Gupta K, Climer J.R., Monaghan C.K., Hasselmo M.E. (2012) Cholinergic modulation of cognitive processing: insights drawn from computational models. Front Behav Neurosci. 6:24. PMCID: PMC3374475. PDF

2011

Yoshida, M., Giocomo, L.M., Boardman, I., Hasselmo, M.E. (2011) Frequency of subthreshold oscillations at different membrane potential voltages in neurons at different anatomical positions on the dorsoventral axis in the rat medial entorhinal cortex. J Neurosci. 31(35):12683-94. PMCID: PMC3177240. PDF

Brandon, M.P., Bogaard, A.R., Andrews, C., Hasselmo, M.E. (2011) Head direction cells in the postsubiculum do not show replay of prior waking sequences during sleep. Hippocampus 22(3):604-618. PMCID: PMC3288437 PDF

Hasselmo, M.E., Sarter, M. (2011) Modes and models of forebrain cholinergic neuromodulation of cognition. Neuropsychopharmacology, 36: 52-73. PMCID: PMC2992803. PDF

Hyman, J.M., Hasselmo, M.E., Seamans, J.K. (2011) What is the functional relevance of prefrontal cortex entrainment to hippocampal theta rhythms? Front. Neurosci. 5: 24. PMCID: PMC3052540. PDF

Navratilova, Z., Giocomo, L.M., Fellous, J.M., Hasselmo, M.E., McNaughton, B.L. (2011) Phase precession and variable spatial scaling in a periodic attractor map model of medial entorhinal grid cells with realistic after-spike dynamics. Hippocampus 22(4):772-789. PDF

2010

Hasselmo, M.E., Giocomo. L.M., Brandon, M.P., Yoshida, M. (2010) Cellular dynamical mechanisms for encoding the time and place of events along spatiotemporal trajectories in episodic memory. Behav. Brain Res. 215: 261-274. PMCID: PMC2891577. PDF

Heys, J.G., Giocomo, L.M., Hasselmo, M.E. (2010) Cholinergic modulation of the resonance properties of stellate cells in layer II of medial entorhinal cortex. J. Neurophysiol. 104(1): 258-70. PMCID: PMC2904208. PDF

Zilli, E.A., Hasselmo, M.E. (2010) Coupled noisy spiking neurons as velocity-controlled oscillators in a model of grid cell spatial firing. J. Neurosci. 30: 13850-13860. PMCID: PMC2978507 PDF

Brown, T.H., Ross, B., Keller, J., Hasselmo, M.E., Stern, C.E. (2010) Which way was I going? Contextual retrieval supports the disambiguation of well-learned overlapping navigational routes. J. Neurosci. 30(21): 7414-22. PMCID: PMC2905880. PDF

Hyman, J.M., Zilli, E.A., Paley, A.M., Hasselmo, M.E. (2010) Working memory performance correlates with prefrontal-hippocampal theta interactions but not with prefrontal neuron firing rates. Front. Integr. Neurosci. 4:2. PMCID: PMC2861479 PDF

2009

Giocomo, L.M., Hasselmo, M.E. (2009) Knock-out of HCN1 subunit flattens dorsal-ventral frequency gradient of medial entorhinal neurons in adult mice. Journal of Neuroscience 29(23): 7625-30. PMCID 2729850. PDF

Yoshida, M., Hasselmo, M.E. (2009) Persistent firing supported by an intrinsic cellular mechanism in a component of the head direction system. Journal of Neuroscience 29(15): 4945-52. PMCID2704018. PDF

Hasselmo, M.E. (2009) A model of episodic memory: Mental time travel along encoded trajectories using grid cells. Neurobiology of Learning and Memory 92(4): 559-73. PDF

Hasselmo, M.E., Brandon, M.P., Yoshida, M., Giocomo, L.M., Heys, J.G., Fransen, E., Newman, E.L., Zilli, E.A. (2009) A phase code for memory could arise from circuit mechanisms in entorhinal cortex. Neural Networks 22(8):1129-38. PDF

Schon, K., Quiroz, Y.T., Hasselmo, M.E., Stern, C.E. (2009) Greater working memory load results in greater medial temporal activity at retrieval. Cereb. Cortex 19(11): 2561-71. PMCID: 2758675. PDF

Zilli, E.A., Yoshida, M., Tahvildari, B., Giocomo, L.M., Hasselmo, M.E. (2009) Evaluation of the oscillatory interference model of grid cell firing through analysis of measured period variance of some biological oscillators. PLoS Comput Biol. 5(11): e1000573. PDF

Brandon, M.P., Hasselmo, M.E. (2009) Sources of the spatial code within the hippocampus. F1000 Biol. Rep. 1.pii: 3. PMCID: PMC2920688. PDF

2008

Giocomo, L.M., Hasselmo, M.E. (2008) Time constant of I(h) differs along dorsal to ventral axis of medial entorhinal cortex. Journal of Neuroscience, 28:9414-25. PDF

Hasselmo, M.E. (2008) Temporally structured replay of neural activity in a model of entorhinal cortex, hippocampus and postsubiculum. Eur. J. Neurosci. 28:1301-1315. PDF

Hasselmo, M.E. (2008) Grid cell mechanisms and function: Contributions of entorhinal persistent spiking and phase resetting. Hippocampus 18(12): 1116-26. PDF

Yoshida, M., Fransen, E., Hasselmo, M.E. (2008) mGluR-dependent persistent firing in entorhinal cortex layer III neurons. Eur. J. Neurosci. 28:1116-26. PDF

Zilli, E.A., Hasselmo, M.E. (2008) Analyses of Markov decision process structure regarding the possible strategic use of interacting memory systems. Frontiers Comput. Neurosci. 2:6. PDF

Giocomo, L.M., Hasselmo, M.E. (2008) Computation by oscillations: Implications of experimental data for theoretical models of grid cells. Hippocampus 18(12): 1186-1199. PDF

Hasselmo, M.E., Brandon, M.P. (2008) Linking cellular mechanisms to behaviour: Entorhinal persistent spiking and membrane potential oscillations may underlie path integration, grid cell firing and episodic memory. Neural Plasticity, 2008: 658323. PDF

Hasselmo, M.E. (2008) Neuroscience. The scale of experience. Science. 321(5885):46-7. Full text

Zilli, E.A., Hasselmo, M.E. (2008) Modeling the role of working memory and episodic memory in behavioral tasks. Hippocampus, 18(2):193-209. PDF

Koene RA, Hasselmo ME. (2008) Reversed and forward buffering of behavioral spike sequences enables retrospective and prospective retrieval in hippocampal regions CA3 and CA1. Neural Networks 21:276-88.

Zilli, E.A., Hasselmo, M.E. (2008) The influence of Markov decision process structure on the possible strategic use of working memory and episodic memory. PloS ONE 3(7): e2756. PDF

2007

Giocomo LM, Zilli EA, Fransen E, Hasselmo ME. (2007) Temporal frequency of subthreshold oscillations scales with entorhinal grid cell field spacing. Science, 315(5819):1719-22. Abstract Full text

Hasselmo ME, Giocomo LM, Zilli EA (2007) Grid cell firing may arise from interference of theta frequency membrane potential oscillations in single neurons. Hippocampus, 17(12): 1252-1271. PDF

Hasselmo ME (2007) Arc length coding by interference of theta frequency oscillations may underlie context-dependent hippocampal unit data and episodic memory function. Learn. Mem. 14: 782-794. PDF

Griffin AL, Eichenbaum H, Hasselmo ME. (2007) Spatial representations of hippocampal CA1 neurons are modulated by behavioral context in a hippocampus-dependent memory task. J Neurosci. 27(9):2416-23 PDF

Tahvildari B, Fransen E, Alonso AA, Hasselmo ME. (2007) Switching between "On" and "Off" states of persistent activity in lateral entorhinal layer III neurons. Hippocampus. 17(4):257-63. PDF

Manns, J.R., Zilli, E.A., Ong, K.C., Hasselmo, M.E., Eichenbaum, H. (2007) Hippocampal CA1 spiking during encoding and retrieval: Relation to theta phase. Neurobiol. Learn. Mem., 87(1):9-20. PDF

Katz Y, Kath WL, Spruston N, Hasselmo ME. (2007) Coincidence detection of place and temporal context in a network model of spiking hippocampal neurons. PLoS Comput Biol. 3(12):e234. PMCID: PMC2134961

Giocomo LM, Hasselmo ME (2007) Neuromodulation by glutamate and acetylcholine can change circuit dynamics by regulating the relative influence of afferent input and excitatory feedback. Mol. Neurobiol. 36(2): 184-200.

2006

Hasselmo, M.E., Stern, C.E. (2006) Mechanisms underlying working memory for novel information. Trends in Cognitive Sciences, 10(11):487-93. PDF

Lee, I., Griffin, A.L., Zilli, E.A., Eichenbaum, H., Hasselmo, M.E. (2006) Gradual translocation of spatial correlates of neuronal firing in the hippocampus toward prospective reward locations. Neuron, 51(5):639-50. PDF

Hasselmo, M.E. (2006) The role of acetylcholine in learning and memory. Curr. Opinion Neurobiol. 16(6): 710-715. PDF

Fransen, E., Tahvildari, B., Egorov, A.V., Hasselmo, M.E. and Alonso, A.A. (2006) Mechanism of graded persistent cellular activity of entorhinal cortex layer V pyramidal neurons. Neuron, 49(5): 735-746. PDF

Zilli, E.A., Hasselmo, M.E. (2006) An analysis of the mean theta phase of population activity in a model of hippocampal region CA1. Network: Computation in Neural Systems, 17(3):277-97. PDF

Giocomo, L.M., Hasselmo, M.E. (2006) Difference in time course of modulation of synaptic transmission by group II versus group III metabotropic glutamate receptors in region CA1 of the hippocampus. Hippocampus. 16(11):1004-16. PDF

Koene, R.A., Hasselmo, M.E. (2006) First-in-first-out item replacement in a model of short-term memory based on persistent spiking. Cereb. Cortex. Epub ahead of print. PDF

Siekmeier, P.J., Hasselmo, M.E., Howard, M.W., Coyle, J. (2006) Modeling of context-dependent retrieval in hippocampal region CA1: Implications for cognitive function in schizophrenia. Schizophr. Res. 89(1-3):177-90. PDF

Kremin, T., Gerber, D., Giocomo, L.M., Huang, S.Y., Tonegawa, S., Hasselmo, M.E. (2006) Muscarinic suppression in stratum radiatum of CA1 shows dependence on presynaptic M1 receptors and is not dependent on effects at GABAB receptors. Neurobiol. Learning and Mem., 85(2):153-163. PDF

2005

Hasselmo, M.E. (2005) A model of prefrontal cortical mechanisms for goal directed behavior. Journal of Cognitive Neuroscience, 17(7):1115-29. PDF MATLAB script demonstrating models

Hasselmo M.E. (2005) What is the function of hippocampal theta rhythm?--Linking behavioral data to phasic properties of field potential and unit recording data. Hippocampus. 15(7):936-49. PDF

Hasselmo, M.E. and Eichenbaum, H. (2005) Hippocampal mechanisms for the context-dependent retrieval of episodes. Neural Networks, 18(9):1172-1190. PDF MATLAB script demonstrating models

Koene, R.A. and Hasselmo, M.E. (2005) An integrate and fire model of prefrontal cortex neuronal activity during performance of goal-directed decision making. Cerebral Cortex, 15(12):1964-81. PDF

Hasselmo, M. (2005) Expecting the unexpected: Modeling of neuromodulation. Neuron 46(4):526-528. PDF

McGaughy J, Koene RA, Eichenbaum H, Hasselmo ME. (2005) Cholinergic deafferentation of the entorhinal cortex in rats impairs encoding of novel but not familiar stimuli in a delayed nonmatch-to-sample task. J Neurosci. 25(44):10273-81. PDF

Hyman JM, Zilli EA, Paley AM, Hasselmo ME (2005) Medial prefrontal cortex cells show dynamic modulation with the hippocampal theta rhythm dependent on behavior. Hippocampus. 15(6):739-49. PDF

Kunec, S., Hasselmo, M., Kopell N. (2005) Encoding and retrieval in the CA3 region of the hippocampus: a model of theta phase separation. J. Neurophysiol. 94(1):70-82. PDF

Schon K, Atri A, Hasselmo ME, Tricarico MD, LoPresti ML, Stern CE (2005) Scopolamine reduces persistent activity related to long-term encoding in the parahippocampal gyrus during delayed matching in humans. J Neurosci. 25(40):9112-23 PDF

Howard MW, Fotedar MS, Datey AV, Hasselmo ME. (2005) The temporal context model in spatial navigation and relational learning: toward a common explanation of medial temporal lobe function across domains. Psychol Rev. 112(1):75-116.

Gorchetchnikov, A. and Hasselmo, M.E. (2005) A biophysical implementation of a bidirectional graph search algorithm to solve multiple goal navigation tasks. Connection Science, 17: 145-164. PDF

Hasselmo, M.E. (2005) The role of hippocampal regions CA3 and CA1 in matching entorhinal input with retrieval of associations between objects and context: theoretical comment on Lee et al. (2005). Behav. Neurosci. 119: 342-345.

Giocomo LM, Hasselmo ME (2005) Nicotinic modulation of glutamatergic synaptic transmission in region CA3 of the hippocampus. Eur J Neurosci. 22(6):1349-56 PDF

Gorchetchnikov A, Versace M, Hasselmo ME (2005) A model of STDP based on spatially and temporally local information: derivation and combination with gated decay. Neural Netw. 18(5-6):458-66. PDF

2004

Hasselmo, M.E. and McGaughy, J. (2004) High acetylcholine levels set circuit dynamics for attention and encoding and low acetylcholine levels set dynamics for consolidation. Progress in Brain Research 145: 207-231. PDF

Judge, S.J. and Hasselmo, M.E. (2004) Theta rhythmic stimulation of stratum lacunosum-moleculare in rat hippocampus contributes to associative LTP at a phase offset in stratum radiatum. J Neurophysiol. 92(3):1615-24. PDF

Wyble, B.P., Hyman, J.M., Rossi, C.A., Hasselmo, M.E. (2004) Analysis of theta power in hippocampal EEG during bar pressing and running behavior in rats during distinct behavioral contexts. Hippocampus, 14(5):662-74. PDF

Schon, K., Hasselmo, M.E., Lopresti, M.L., Tricarico, M.D., and Stern, C.E. (2004) Persistence of parahippocampal representation in the absence of stimulus input enhances long-term encoding: A functional magnetic resonance imaging study of subsequent memory after a delayed match-to-sample task. J. Neurosci. 24: 11088-97. PDF

Fransen, E., Alonso AA, Dickson CT, Magistretti J, Hasselmo, M.E. (2004) Ionic mechanisms in the generation of subthreshold oscillations and action potential clustering in entorhinal layer II stellate neurons. Hippocampus, 14(3):368-84. PDF

Atri, A., Sherman, S.J., Norman, K.A., Kirchhoff, B.A., Nicolas, M.M., Greicius, M.D., Cramer, S.C., Breiter, H.C., Hasselmo, M.E., Stern, C.E. (2004) Blockade of central cholinergic receptors impairs new learning and increases proactive interference in a word paired-associate memory task. Behavioral Neurosci. 118(1):223-236. PDF

2003

Hyman, J.M., Wyble, B.P., Goyal, V., Rossi, C.A., Hasselmo, M.E. (2003) Stimulation in hippocampal region CA1 in behaving rats yields LTP when delivered to the peak of theta and LTD when delivered to the trough. J. Neurosci. 23(37):11725-31. PDF

Linster, C., Maloney, M., Patil, M. and Hasselmo, M.E. (2003) Enhanced cholinergic suppression of previously strengthened synapses enables the formation of self-organized representations in olfactory cortex. Neurobiol. Learn. Mem. 80(3): 302-314. PDF

Koene, R.A., Gorchetchnikov, A., Cannon, R.C. and Hasselmo M.E. (2003) Modeling goal-directed spatial navigation in the rat based on physiological data from the hippocampal formation. Neural Networks 16(5-6):577-84. PDF

Sherman, S.J., Atri, A., Hasselmo, M.E., Stern, C.E., Howard, M.W. (2003) Scopolamine impairs human recognition memory: Data and modeling. Behavioral Neuroscience, 117(3): 526-539.

2002

Molyneaux, B.J., Hasselmo, M.E. (2002) GABA(B) Presynaptic Inhibition Has an In Vivo Time Constant Sufficiently Rapid to Allow Modulation at Theta Frequency. J Neurophysiol. 87(3):1196-205. PDF

Fransen, E., Alonso, A.A. and Hasselmo, M.E. (2002) Simulations of the role of the muscarinic-activated calcium-sensitive non-specific cation current I(NCM) in entorhinal neuronal activity during delayed matching tasks. J. Neurosci. 22(3):1081-1097. PDF

Hasselmo, M.E., Hay, J., Ilyn, M. and Gorchetchnikov, A. (2002) Neuromodulation, theta rhythm and rat spatial navigation. Neural Networks, 15: 689-707. PDF

Egorov, A.V., Hamam, B.N., Fransen, E., Hasselmo, M.E., Alonso, A.A. (2002) Graded persistent activity in entorhinal cortex neurons. Nature 420(6912):173-8. PDF

Cannon, RC, Hasselmo, ME and Koene, RA (2002) From biophysics to behavior: Catacomb2 and the design of biologically plausible models for spatial navigation. Neuroinformatics, 1(1): 3-42. PDF

2001

Hasselmo, M.E. and Fehlau, B.P. (2001) Differences in time course of cholinergic and GABAergic modulation of excitatory synaptic potentials in rat hippocampal slice preparations. J. Neurophysiol., 86: 1792-1802. PDF

Stern, C.E., Sherman, S.J., Kirchhoff, B.A. and Hasselmo, M.E. (2001) Medial temporal and prefrontal contributions to working memory tasks with novel and familiar stimuli. Hippocampus, 11: 337-346. PDF

Linster C, Hasselmo ME. (2001) Neuromodulation and the Functional Dynamics of Piriform Cortex. Chem Senses, 26(5):585-594. PDF

De Rosa E, Hasselmo ME, Baxter MG (2001) Contribution of the cholinergic basal forebrain to proactive interference from stored odor memories during associative learning in rats. Behav Neurosci. 115(2):314-27.

2000

Wyble, B.P., Linster, C. and Hasselmo, M.E. (2000) Size of CA1-evoked synaptic potentials is related to theta rhythm phase in rat hippocampus. J. Neurophysiol. 83: 2138-2144. PDF

DeRosa, E. and Hasselmo, M.E. (2000) Muscarinic cholinergic neuromodulation reduces proactive interference between stored odor memories during associative learning in rats. Behav. Neurosci. 114: 32-41.

Linster, C. and Hasselmo, M.E. (2000) Neural activity in the horizontal limb of the diagonal band of Broca can be modulated by electrical stimulation of the olfactory bulb and cortex in rats. Neurosci. Lett. 282: 157-160. PDF

Dickson, C.T., Magistretti, J., Shalinsky, M.H., Fransen, E., Hasselmo, M.E., Alonso, A. (2000) Properties and role of I(h) in the pacing of subthreshold oscillations in entorhinal cortex layer II neurons. J Neurophysiol. 83(5):2562-79. PDF

Sohal, V. and Hasselmo, M.E. (2000) A model for experience-dependent changes in the responses of inferotemporal neurons. Network: Comp. Neural Syst. 11: 169-190. PDF

1999

Stern, C.E. and Hasselmo, M.E. (1999) Bridging the gap: Integrating cellular and functional magnetic resonance imaging studies of the hippocampus. Hippocampus 9: 45-53.

Hasselmo, M.E. and McClelland, J.L. (1999) Neural models of memory. Curr. Opinion Neurobiol. 9: 184-188. PDF

Hasselmo, M.E. (1999) Neuromodulation: Acetylcholine and memory consolidation. Trends in Cognitive Sciences 3: 351-359. PDF

Linster, C., Wyble, B. and Hasselmo, M.E. (1999) Electrical stimulation of the horizontal limb of the diagonal band of broca modulates population EPSPs in piriform cortex, J. Neurophysiology 81: 2737-2742. PDF

Patil, M.M. and Hasselmo, M.E. (1999) Modulation of inhibitory synaptic potentials in the piriform cortex. J. Neurophysiol. 81(5): 2103-2118. PDF

Linster, C and Hasselmo, M.E. (1999) Behavioral responses to aliphatic aldehydes can be predicted from electrophysiological responses of mitral cells in the olfactory bulb. Physiology and Behavior, 66(3): 497-502.

Fransen, E., Wallenstein, G.V., Alonso, A., Dickson, C.T. and Hasselmo, M.E. (1999) A biophysical simulation of intrinsic and network properties of entorhinal cortex. Neurocomputing 26-27: 375-380.

Knowles RB, Wyart C, Buldyrev SV, Cruz L, Urbanc B, Hasselmo ME, Stanley HE, Hyman BT (1999) Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease. Proc Natl Acad Sci U S A 96(9):5274-9.

Kwon JS, O'Donnell BF, Wallenstein GV, Greene RW, Hirayasu Y, Nestor PG, Hasselmo ME, Potts GF, Shenton ME, McCarley RW. (1999) Gamma frequency-range abnormalities to auditory stimulation in schizophrenia. Arch Gen Psychiatry. 56(11):1001-5.

1998

Wallenstein, G.V., Eichenbaum, H.B. and Hasselmo, M.E. (1998) The hippocampus as an associator of discontiguous events. Trends Neurosci. 21: 317-323. PDF

Sohal, V.S. and Hasselmo, M.E. (1998) Changes in GABAB modulation during a theta cycle may be analogous to the fall of temperature during annealing. Neural Computation, 10: 889-902. PDF

Patil, M.M., Linster, C., Lubenov, E. and Hasselmo, M.E. (1998) Cholinergic agonist carbachol enables associative long-term potentiation in piriform cortex slices. J. Neurophysiol. 80: 2467-2474. PDF

Sohal, V.S. and Hasselmo, M.E. (1998) GABAB modulation improves sequence disambiguation in computational models of hippocampal region CA3. Hippocampus 8:171-193.

Myers, C.E., Ermita, B.R., Hasselmo, M. and Gluck, M.A. (1998) Further implications of a computational model of septohippocampal cholinergic modulation in eyeblink conditioning. Psychobiol. 26: 1-20.

1997

Hasselmo, M.E., Linster, C., Ma, D. and Cekic, M. (1997) Noradrenergic suppression of synaptic transmission may influence cortical "signal-to-noise" ratio. J. Neurophysiol. 77: 3326-3339. PDF

Barkai, E., Hasselmo, M.E. (1997) Acetylcholine and associative memory in the piriform cortex. Mol Neurobiol. 15(1):17-29.

Hasselmo, M.E. and Wyble, B.P. (1997) Simulation of the effects of scopolamine on free recall and recognition in a network model of the hippocampus. Behav. Brain Res. 89: 1-34. PDF

Wallenstein, G.V. and Hasselmo, M.E. (1997a) GABAergic modulation of hippocampal activity: Sequence learning, place field development, and the phase precession effect. Journal of Neurophysiology, 78: 393-408. PDF

Hasselmo, M.E. (1997) A computational model of the progression of Alzheimer's disease. M.D. Computing 14: 181-191. PDF

Wallenstein, G.V. and Hasselmo, M.E. (1997b) Functional transitions between epileptiform-like activity and associative memory in hippocampal region CA3. Brain Research Bulletin, 43: 485-493.

Linster, C., Hasselmo, M.E. (1997) Modulation of inhibition in a model of olfactory bulb reduces overlap in the neural representation of olfactory stimuli. Behav. Brain Res. 84: 117-127. PDF

1996

Hasselmo, M.E., Wyble, B.P. and Wallenstein, G.V. (1996) Encoding and retrieval of episodic memories: Role of cholinergic and GABAergic modulation in the hippocampus. Hippocampus, 6(6): 693-708. PDF

Hasselmo, M.E. and Cekic M. (1996) Suppression of synaptic transmission allows combination of associative feedback and self-organizing feedforward connections in a model of neocortex. Behav. Brain Res. 79: 153-161. PDF

Grunze, H.C.R., Rainnie, D.G., Hasselmo, M.E., Barkai, E., Heam, E.F., McCarley, R.W., Greene, R.W. (1996) NMDA-dependent modulation of CA1 local circuit inhibition. J. Neurosci. 16: 2034- 2043.

Tang, A.C. and Hasselmo, M.E. (1996) Effect of long-term baclofen treatment on recognition memory and novelty detection. Behav. Brain Res. 74: 145-152. PDF

Myers, C.E., Ermita, B.R., Harris, K., Hasselmo, M.E., Solomon, P. and Gluck, M.A. (1996) A computational model of cholinergic disruption of septo-hippocampal activity in classical eyeblink conditioning. Neurobiol. Learning and Memory, 66: 2034-2043.

1995

Hasselmo, M.E. (1995) Neuromodulation and cortical function: Modeling the physiological basis of behavior. Behav. Brain Res. 67: 1-27. PDF

Hasselmo, M.E., Schnell, E., Barkai, E. (1995) Dynamics of learning and recall at excitatory recurrent synapses and cholinergic modulation in hippocampal region CA3. J. Neurosci. 15(7): 5249-5262. PDF MATLAB script demonstrating model

Hasselmo, M.E. and Barkai, E. (1995) Cholinergic modulation of activity-dependent synaptic plasticity in rat piriform cortex. J. Neurosci. 15(10): 6592-6604. PDF

Liljenstrom H. and Hasselmo M.E. (1995) Cholinergic modulation of cortical oscillatory dynamics. J. Neurophysiol. 74: 288-297.

1994

Hasselmo, M.E. and Schnell, E. (1994) Laminar selectivity of the cholinergic suppression of synaptic transmission in rat hippocampal region CA1: computational modeling and brain slice physiology. J. Neurosci. 14(6): 3898-3914. PDF

Barkai E. and Hasselmo M.E. (1994) Modulation of the input/output function of rat piriform cortex pyramidal cells. J. Neurophysiol. 72: 644-658.

Barkai E., Bergman, R.E., Horwitz, G. and Hasselmo M.E. (1994) Modulation of associative memory function in a biophysical simulation of rat piriform cortex. J. Neurophysiol. 72: 659-677.

Hasselmo M.E. (1994) Runaway synaptic modification in models of cortex: Implications for AlzheimerÂ¹s disease. Neural Networks 7(1): 13-40. PDF

Tang, A.C. and Hasselmo, M.E. (1994) Selective suppression of intrinsic but not afferent fiber synaptic transmission by baclofen in the piriform (olfactory) cortex. Brain Res. 659: 75-81.

1993

Hasselmo M.E. (1993) Acetylcholine and learning in a cortical associative memory. Neural Computation. 5(1): 32-44.

Hasselmo M.E. and Bower J.M. (1993) Acetylcholine and memory. Trends Neurosci. 16(6): 218-222. PDF

1992

Hasselmo M.E. and Bower J.M. (1992) Cholinergic suppression specific to intrinsic not afferent fiber synapses in rat piriform (olfactory) cortex. J. Neurophysiol. 67: 1222-1238.

Hasselmo M.E., Anderson B.P. and Bower J.M. (1992) Cholinergic modulation of cortical associative memory function. J. Neurophysiol. 67: 1239-1246.

1991

Hasselmo M.E. and Bower J.M. (1991) Selective suppression of afferent but not intrinsic fiber synaptic transmission by 2-amino-4-phosphonobutyric acid (AP4) in piriform cortex. Brain Research. 548: 248-255.

1990

Hasselmo M.E. and Bower J.M. (1990) Afferent and association fiber differences in short-term potentiation in piriform (olfactory) cortex of the rat. J. Neurophysiol. 64:179-190.

1989

Hasselmo M.E., Rolls E.T., Baylis G.C. (1989a) The role of expression and identity in the face-selective responses of neurons in the temporal visual cortex of the monkey. Behav. Brain Res. 32:203-218.

Hasselmo M.E., Rolls E.T., Baylis G.C., Nalwa V. (1989b) Object-centered encoding by face-selective neurons in the cortex in the superior temporal sulcus of the monkey. Exp. Brain Res. 75(2):417-429.

Rolls E.T., Baylis G.C., Hasselmo M.E., Nalwa V. (1989) The effect of learning on the face selective responses of neurons in the cortex in the superior temporal sulcus of the monkey. Exp. Brain Res. 76:153-164

1987

Rolls E.T., Baylis G.C., Hasselmo M.E. (1987) The responses of neurons in the cortex in the superior temporal sulcus of the monkey to band-pass spatial frequency filtered faces. Vision Res. 27:311-326.

EDITED BOOKS AND JOURNAL SPECIAL ISSUES:

Wunsch, D.C., Hasselmo, M.E., Venayagamoorthy, G.K. and Wang, D. (2003) Advances in Neural Network Research. IJCNN 2003. Pergamon (Elsevier): Boston.

Doya, K., Dayan, P. and Hasselmo, M.E. (2002) Special issue: Computational Models of Neuromodulation. Neural Networks.

Touretzky, D.S., Mozer, M.C. and Hasselmo, M.E. (1996) Advances in Neural Information Processing Systems 8. MIT Press: Cambridge, MA.

BOOK CHAPTERS:

Michael E. Hasselmo (2011) Models of hippocampus. Scholarpedia, 6(5):1371

Hasselmo, M.E., Cannon, R.C. and Koene, R. (2002) A simulation of parahippocampal and hippocampal structures guiding spatial navigation of a virtual rat in a virtual environment: A functional framework for theta theory. In: Witter, M.P. and Wouterlood, F. (eds.) The Parahippocampal Region: Organization and Role in Cognitive Function. Oxford University Press: London. PDF

Hasselmo, M.E., Wyble, B.P. and Cannon, R.C. (2001) From spike frequency to free recall: How neural circuits perform encoding and retrieval. In: A. Parker, T.J. Bussey, E. Wilding (eds.) The Cognitive Neuroscience of Memory: Encoding and Retrieval. Psychology Press: London. PDF

Hasselmo, M.E. (2003) Theta theory: Requirements for encoding events and task rules explain theta phase relationships in hippocampus and neocortex. Proc. Intl Joint Conf. on Neural Networks, 2003. PDF

Gorchetchnikov, A. and Hasselmo, M.E. (2003) Timing of consecutive traveling pulses in a model of entorhinal cortex. . Proc. Intl Joint Conf. Neural Networks, 2003. PDF

Hasselmo, M.E. and Kapur, A. (2001) Modeling of large networks. In: E. DeSchutter (ed.) Computational Neuroscience: Realistic modeling for experimentalists. CRC Press: New York, pp. 289-316.

Hasselmo, M.E., Fransen, E., Dickson, C., Alonso, A. (2000) Computational modeling of entorhinal cortex. Ann. NY Acad. Sci. 911: 418-446.

Hasselmo, M.E. (1999) Neuromodulation and the hippocampus: memory function and dysfunction in a network simulation. Prog. Brain Res. 121: 3-18.

Hasselmo, M.E. (1999) Septal modulation of hippocampal activity: What is the function of the theta rhythm? In: R. Numan (ed.) The Behavioral Neuroscience of the Septal Region. Springer-Verlag: New York. pp. 92-114.

Hasselmo, M. E., Wyble, B.P., & Stern, C.E. (1998). A model of human memory based on the cellular physiology of the hippocampal formation. In R. W. Parks, D. S. Levine & D. L. Long (Eds.), Fundamentals of neural network modeling: Neuropsychology and cognitive neuroscience (pp. 299-329). Cambridge, MA: MIT Press.

Hasselmo, M.E. and Linster, C. (1998) Neuromodulation and memory function. In: P.S. Katz (ed.) Beyond Neurotransmission: The Role of Neuromodulation in Information Flow and Neuronal Circuit Flexibility. Oxford University Press, Oxford, U. K.

Fransen, E., Wallenstein, G.V., Alonso, A., Dickson, C.T. and Hasselmo, M.E. (1998) A biophysical simulation of intrinsic and network properties of entorhinal cortex. In: J.M. Bower (ed.) Neurocomputing: Proceedings of the Computational Neuroscience Conference, Elsevier.

Hasselmo, M.E. and Linster, C. (1998) Acetylcholine and frontal cortex "signal-to-noise" ratio. In: B.L. Miller and J. Cummings (eds.) The Human Frontal Lobes: Function and Disorders. Guilford Press: New York, pp. 139-158.

M. Petrides, J. McGaugh, M. Gluck, D. Schacter, F. Keil, A. Martin, L. Cahill, H. Eichenbaum, M. Hasselmo, J. Murre, C. Myers, B. Roozendaal, D. Simons, W.C. Smith, and C. Williams (1998) Learning and Memory: Systems. In M.J. Zigmond, F.E. Bloom, S.C. Landis, J.L. Roberts, L.R. Squire (eds.) Fundamental Neuroscience, Academic Press: New York.

Hasselmo, M.E. and Wyble, B.P. (1997) Does the spread of Alzheimer's disease neuropathology involve the mechanisms of consolidation? In: J.A. Reggia, E. Ruppin, R.S.Berndt (eds.) Neural Modeling of Brain and Cognitive Disorders. World Scientific Publishing, London, pp. 43-62.

Stern, C.E. and Hasselmo, M.E. (1997) Functional magnetic resonance imaging and computational modeling: An integrated study of hippocampal function. In: J.M. Bower (ed.) Computational Neuroscience: Trends in Research, 1997. Plenum Press: New York, pp. 859-865.

Hasselmo, M.E. and Linster, C. (1998) Modeling the piriform cortex. In P.S. Ulinski, E.G. Jones and A. Peters (eds.) Cerebral Cortex, Volume 13: Models of cortical circuits. Kluwer Academic: Plenum Press, New York, pp. 525-560.

Sohal, V.S. and Hasselmo, M.E. (1997) A model of changes in inferotemporal activity during a delayed-match-to-sample task. In: J.M. Bower (ed.) Computational Neuroscience: Trends in Research, 1997. Plenum Press: New York, 845-850.

Linster, C. and Hasselmo, M.E. (1997) Short term memory function in a model of the olfactory system. In J.M. Bower (ed.) Computational Neuroscience, Trends in Research, 1997. Plenum Press: New York.

Patil, M. , Linster, C. and Hasselmo, M.E. (1997) Cholinergic modulation of inhibitory synaptic transmission in the piriform cortex. In J.M.Bower, (ed.) Computational Neuroscience, Trends in Research, 1997. Plenum Press: New York, pp. 159-165.

Hasselmo, M.E. and Cekic, M. (1996) Cholinergic suppression of transmission may allow combined associative memory function and self-organization in the neocortex. In: Touretzky, D.S., Mozer, M.C. and Hasselmo, M.E. (eds.) Advances in Neural Information Processing Systems 8. MIT Press: Cambridge, MA, pp. 131-137.

Hasselmo, M.E. and Cekic, M. (1995) Modulation in the neocortex: Physiological mechanisms for self-supervised learning. In: J.M. Bower (ed.) Computation and Neural Systems, Vol. 4 Kluwer Academic Publishers: Norwell, MA.

Tang, A.C. and Hasselmo, M.E. (1996) To recognize the new, must one remember the old? -- GABAergic modulation and its computational and behavioral consequences. In: J.M. Bower (ed.) Computational Neuroscience, Academic Press: New York.

Hasselmo, M.E. and Stern, C.E. (1995) Linking LTP to network function: A simulation of episodic memory in the hippocampal formation. In M. Baudry and J. Davis (eds.) Long-term potentiation, Vol. 3. MIT Press, Cambridge, MA.

Hasselmo, M.E. (1995) Physiological constraints on models of behavior. In L. Niklasson, M.B. Boden (eds.) Current Trends in Connectionism. Lawrence Erlbaum Assoc.; Hillsdale, NJ, p. 15-32.

Hasselmo, M.E., Schnell, E., Berke, J. and Barkai, E. (1995) A model of the hippocampus combining self-organization and associative memory function. In G. Tesauro, D. Touretzky, T. Leen (eds.) Advances in Neural Information Processing Systems, Vol. 7. MIT Press: Cambridge, MA.

Hasselmo, M.E. and Schnell, E. (1994) Feedback regulation of cholinergic modulation and hippocampal memory function. In J.M. Bower (ed.) Computation and Neural Systems, Vol. 3. Kluwer Academic Publishers: Norwell, MA.

Hasselmo, M.E., Barkai, E., Horwitz, G. and Bergman R.E. (1993) Modulation of neuronal adaptation and cortical associative memory function. In F. Eeckman and J.M. Bower (eds.) Computation in Neurons and Neural Systems, Vol. 2. Kluwer Academic Publishers: Norwell, MA.

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