Chunyu Liu
Profiles

Chunyu Liu, PhD

Professor, Biostatistics - Boston University School of Public Health

(617) 638-5104
liuc@bu.edu
Talbot
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Biography

Dr. Chunyu Liu earned her PhD in Biostatistics with a specialization in statistical genetics from the Department of Biostatistics at Boston University. She embarked on her professional journey at Biogen Idec Inc. in Cambridge, Massachusetts, where she served as a statistical geneticist. Additionally, she made significant contributions to the Population Sciences Branch & Framingham Heart Study (FHS), NHLBI, located in Framingham, Massachusetts.
Throughout her career, Dr. Liu has been actively engaged in diverse projects assessing risk factors associated with cardiovascular disease (CVD) and Alzheimer’s disease (AD). Her notable portfolio includes leadership roles as the Principal Investigator (PI) for three R01 grants and an R21 grant since 2018. Moreover, she serves as a subcontract PI for two R21 grants and has secured funding from the Cure Alzheimer’s Fund. In collaborative endeavors, she plays a pivotal role as the lead biostatistician in several R01 grants, contributing to over 135 peer-reviewed manuscripts. Dr. Liu often holds significant authorship positions in these publications, including as the first, second, or last author in more than 40 papers.
Dr. Liu's contributions span significant collaborative research endeavors, where she has held key roles as the lead statistician and co-convener in multiple working groups within the Cohorts for Heart and Aging Research in Genetic Epidemiology (CHARGE). Currently, she serves as a co-convener of the Trans-Omics for Precision Medicine (TOPMed) Mitochondrial DNA (mtDNA) working group, leading efforts to develop analytical methods for mtDNA sequence variations.
Furthermore, Dr. Liu shares her expertise as a member of the NIH’s Genetics of Health and Disease Study Section within the Center for Scientific Review. Her commitment extends to editorial responsibilities, acting as an Associate Editor for the Cardiovascular Digital Health Journal and an Academic Editor for PLOS ONE. Additionally, she plays an active role in the International Genetic Epidemiology Society, co-chairing its Education Committee.

Other Positions

  • Investigator - Framingham Heart Study
  • Member, Evans Center for Interdisciplinary Biomedical Research - Boston University

Education

  • Boston University, PhD Field of Study: Biostatistics
  • University of Maine, PhD Field of Study: Biochemistry
  • Boston University, MA Field of Study: Biostatistics

Websites

Classes Taught

  • SPHBS800
  • SPHBS852
  • SPHBS901

Publications

  • Published on 5/1/2026

    Tao Q, Han J, Ang TFA, Hou L, Liu C, Murabito JM, Lunetta KL, Mez J, Alosco ML, Stein TD, Zhang X, Au R, Farrer L, Palmisano JN, Hamburg NM, Qiu WQ. Peripheral vascular function, including endothelium-dependent measures, and dementia risk: The Framingham Heart Study. Alzheimers Dement. 2026 May; 22(5):e71396. PMID: 42050369.

     Read At: PubMed
  • Published on 4/29/2026

    Yang J, Ogunsola S, Wong J, Wang A, Joehanes R, Levy D, Sharma S, Liu C, Xie J. A mammalian genomic signature shaped by single nucleotide variants regulates transcriptome integrity and diversity. Genome Biol. 2026 Apr 29. PMID: 42057098.

     Read At: PubMed
  • Published on 4/14/2026

    Frank B, Gurnani A, Hurley L, Guan C, Andersen SL, Devine SA, O'Connor MK, Budson A, Liu C, Lin H, Auerbach S, Liu Y, Libon DJ, Price CC, Farrer L, Mez J, Ang A, Au R. Psychometric modeling of Boston process approach data for dementia prediction in the Framingham Heart Study. J Int Neuropsychol Soc. 2026 Apr 14; 1-12. PMID: 41975557.

     Read At: PubMed
  • Published on 3/31/2026

    Gao T, Zheng Y, Joyce BT, Liu L, Liu L, Kiefe C, Forrester S, Gordon-Larsen P, Liu C, Lloyd-Jones D, Zhang K, Hou L. Developing a novel index for neighborhood social determinants of cardiovascular diseases in the CARDIA study. Nat Commun. 2026 Mar 31. PMID: 41917033.

     Read At: PubMed
  • Published on 3/16/2026

    Pinheiro A, Karjadi C, Tripodis Y, Kolachalama VB, Lunetta K, Demissie S, Liu C, Au R, Mohammed S. Predicting cognitive impairment using novel functional features of spatial proximity and circularity in the digital clock drawing test. medRxiv. 2026 Mar 16. PMID: 41891039.

     Read At: PubMed
  • Published on 3/5/2026

    Leng Y, Ding H, Li Y, Liu X, Wang M, Cao Y, Lyu C, Levy D, Ma J, Liu C. Sex-Specific Fifteen-Year Alcohol Consumption Trajectories and Their Association with Cardiovascular Events and Mortality: The Framingham Heart Study. Nutrients. 2026 Mar 05; 18(5). PMID: 41830019.

     Read At: PubMed
  • Published on 2/18/2026

    Ding H, Orwig TA, Rong J, Tatere HY, Liu C, Schramm E, Pathiravasan CH, Murabito JM, Lin H. Associations Between Smartphone-Based Finger Tapping and Cognitive Performance in Older Adults: Observational Study. J Med Internet Res. 2026 Feb 18; 28:e82463. PMID: 41707186.

     Read At: PubMed
  • Published on 2/10/2026

    Gifford KA, Rong J, Schramm E, Zhang Y, Pathiravasan CH, Benjamin EJ, Lin H, Liu C, Au R, Libon DJ, Murabito JM. Digital Stroop Test as a neurocognitive marker in a community-based sample of older adults: Data from the Framingham Heart Study. J Alzheimers Dis. 2026 Mar; 110(1):463-470. PMID: 41668525.

     Read At: PubMed
  • Published on 1/25/2026

    Sun X, Liu X, Bulekova K, Pitsillides AN, Guo X, Yong Q, Raffield LM, Rotter JI, Rich SS, Abecasis G, Carson AP, Vasan RS, Bis JC, Psaty BM, Boerwinkle E, Fitzpatrick AL, Satizabal CL, Arking DE, Ding J, Levy D, Liu C. ASSOCIATION ANALYSIS OF MITOCHONDRIAL HETEROPLASMIC VARIANTS AND CARDIOMETABOLIC TRAITS. medRxiv. 2026 Jan 25. PMID: 41659078.

     Read At: PubMed
  • Published on 1/12/2026

    Zhang Y, Joehanes R, Huan T, Weber LM, Yang Q, Lunetta KL, Levy D, Liu C. Integration of latent factor analysis into multivariable Mendelian randomization. Eur J Epidemiol. 2026 Jan 12. PMID: 41524881.

     Read At: PubMed

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