Tuhina Neogi, MD, PhD
Professor, Epidemiology - Boston University School of Public Health
Biography
I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 300 peer-reviewed publications to date. I am a past chair of the FDA Arthritis Advisory Committee, serve(d) on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year), and the 2022 OARSI Clinical Research Award (in recognition of important contributions to OA research). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I also developed and led the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.
Expertise includes:
- Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
- Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
- Classification criteria and outcome measures in rheumatic diseases.
- Novel methodology to address challenging epidemiologic issues
Other Positions
- Professor, Medicine - Boston University Chobanian & Avedisian School of Medicine
- Chief, Medicine - Boston Medical Center
- Investigator - Framingham Heart Study
- Member, Arthritis & Autoimmune Diseases Research Center - Boston University
- Member, Evans Center for Interdisciplinary Biomedical Research - Boston University
- Section Chief of Rheumatology, Medicine - Boston University Chobanian & Avedisian School of Medicine
Education
- University of Toronto, MD Field of Study: Medicine
- Boston University School of Public Health, PhD Field of Study: Epidemiology
- McMaster University, BS Field of Study: Biochemistry
Publications
- Published on 3/2/2024
Mahmoudian A, King LK, Liew JW, Wang Q, Appleton CT, Englund M, Haugen IK, Lohmander LS, Runhaar J, Turkiewicz A, Neogi T, Hawker GA. Timing is everything: Towards classification criteria for early-stage symptomatic knee osteoarthritis. Osteoarthritis Cartilage. 2024 Mar 02. PMID: 38437945.
Read At: PubMed
- Published on 2/19/2024
Liew JW, Jarraya M, Guermazi A, Lynch J, Felson D, Nevitt M, Lewis CE, Torner J, Roemer FW, Crema MD, Wang N, Becce F, Rabasa G, Pascart T, Neogi T. Intra-Articular Mineralization on Computerized Tomography of the Knee and Risk of Cartilage Damage: The Multicenter Osteoarthritis Study. Arthritis Rheumatol. 2024 Feb 19. PMID: 38369918.
Read At: PubMed
- Published on 12/28/2023
Aoyagi K, Jafarzadeh SR, Carlesso L, Frey Law L, Lewis CE, Nevitt M, Neogi T. Mediating Effect of Pain Sensitization on the Paradoxical Relation of Taking Opioids to Pain Severity in Knee Osteoarthritis: The Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). 2024 Mar; 76(3):403-408. PMID: 37750238.
Read At: PubMed
- Published on 12/26/2023
Helget LN, O'Dell JR, Newcomb JA, Androsenko M, Brophy MT, Davis-Karim A, England BR, Ferguson R, Pillinger MH, Neogi T, Palevsky PM, Wu H, Kramer B, Mikuls TR. Determinants of Achieving Serum Urate Goal with Treat-to-Target Urate-Lowering Therapy in Gout. Arthritis Rheumatol. 2024 Apr; 76(4):638-646. PMID: 37842953.
Read At: PubMed
- Published on 10/15/2023
Liew JW, Jarraya M, Guermazi A, Lynch J, Wang N, Rabasa G, Jafarzadeh SR, Nevitt M, Torner J, Lewis CE, Felson DT, Neogi T. Relation of Intra-Articular Mineralization to Knee Pain in Knee Osteoarthritis: A Longitudinal Analysis in the MOST Study. Arthritis Rheumatol. 2023 Dec; 75(12):2161-2168. PMID: 37410792.
Read At: PubMed
- Published on 10/3/2023
Centor RM, Neogi T. Web Exclusive. Annals On Call - Low-Dose Colchicine and Incident Knee and Hip Replacements. Ann Intern Med. 2023 Oct; 176(10):eA220019. PMID: 37782916.
Read At: PubMed
- Published on 9/22/2023
Lee S, Neogi T, Costello KE, Senderling B, Stefanik JJ, Frey-Law L, Kumar D. Association of mechanical temporal summation of pain with muscle co-contraction during walking in people with knee osteoarthritis. Clin Biomech (Bristol, Avon). 2023 Dec; 110:106105. PMID: 37778085.
Read At: PubMed
- Published on 9/22/2023
Baker JF, Olave M, Leach W, Doherty CR, Gillcrist RL, White DK, Ogdie A, England BR, Wysham K, Quinones M, Xiao R, Neogi T, Scanzello CR. Corticosteroid Injections for Symptomatic Treatment of Osteoarthritis of the Knee: A Pilot Blinded Randomized Trial. ACR Open Rheumatol. 2023 Oct; 5(10):529-535. PMID: 37740448.
Read At: PubMed
- Published on 9/13/2023
Neelapala YVR, Neogi T, Kumar D, Jarraya M, Macedo L, Kobsar D, Hanna S, Frey-Law LA, Lewis CE, Nevitt M, Appleton T, Birmingham T, Carlesso LC. Exploring different models of pain phenotypes and their association with pain worsening in people with early knee osteoarthritis: The MOST cohort study. Osteoarthritis Cartilage. 2024 Feb; 32(2):210-219. PMID: 37709187.
Read At: PubMed
- Published on 9/11/2023
Neogi T, Colloca L. Placebo effects in osteoarthritis: implications for treatment and drug development. Nat Rev Rheumatol. 2023 Oct; 19(10):613-626. PMID: 37697077.
Read At: PubMed
View 344 more publications:View Full Profile at BUMC
News & In the Media
- Published on March 7, 2024
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Published on March 1, 2024
Groundbreaking Study Uncovers How Calcium Crystals in Knees Accelerate Arthritis Progression
- Published on March 1, 2024
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Published on January 21, 2022
Colchicine as COVID-19 Treatment Suffers Difficult Year, but Some Hope Remains
- Published on February 26, 2021
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Published on September 16, 2020
How Top Experts Are Advancing Gout Care in the United States
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Published on September 9, 2020
Study: Why People With Knee Osteoarthritis Experience Different Kinds of Pain.
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Published on September 9, 2020
Scientists Discover Key Cause of Different Kinds of Pain Suffered by Osteoarthritis Patients
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Published on September 9, 2020
Tuhina Neogi, MD, PhD, National Leader in Gout Management, on New ACR Guidelines
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Published on September 8, 2020
Study: Why People With Knee Osteoarthritis Experience Different Kinds of Pain
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Published on September 8, 2020
Osteoarthritis Gives Us Unbearable Pain. Why Does It Happen?
- Published on August 10, 2020
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Published on August 10, 2020
Study Finds Bone Drug May Be Beneficial for Knee Osteoarthritis
- Published on July 31, 2020
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Published on July 23, 2020
Coronavirus Fears Keep Patients With Severe Chronic Pain From Seeking Care
- Published on May 13, 2020
- Published on April 8, 2020
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Published on April 7, 2020
Obesity Increases Likelihood of Long-Term Prescription Opioid Use, Researchers Find
- Published on April 2, 2020
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Published on December 19, 2019
Canagliflozin May Reduce Gout Flare Risk in People with Type 2 Diabetes
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Published on December 18, 2019
SGLT2 Inhibitor Canagliflozin Reduces Gout Flares in Type 2 Diabetes: CANVAS Program
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Published on December 17, 2019
Failure of Management: Treatment Gaps at the Root of Dismal Gout Care
- Published on December 16, 2019
- Published on December 16, 2019
- Published on December 14, 2019
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Published on December 13, 2019
Boston University Finds Concerns about Other Painkillers Contributed to Opioid Crisis
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Published on December 13, 2019
Health Risks of NSAIDs Led to ‘Significant Under-Treatment of Pain’
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Published on November 18, 2019
Gout Guidelines Call for Treat-To-Target Strategy Using Allopurinol
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Published on November 15, 2019
ACR: Draft OA Guidelines Stress Non-Drug Tx, Leave Opioid Door Open
- Published on November 13, 2019
- Published on November 12, 2019
- Published on May 2, 2019
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Published on April 19, 2019
Dietary Omega-3 Fatty Acids Linked to Lower Risk of Recurrent Gout Flare
- Published on March 28, 2019
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Published on November 5, 2018
Becoming More Sensitive to Pain Increases Risk of Knee Pain Not Going Away
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Published on November 2, 2018
Becoming More Sensitive to Pain Increases the Risk of Knee Pain Not Going Away
- Published on October 24, 2018
- Published on October 24, 2018
- Published on October 24, 2018
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Published on October 24, 2018
Un medicamento para la gota puede proteger contra la enfermedad renal crónica
- Published on October 9, 2018
- Published on October 9, 2018
- Published on October 9, 2018
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Published on October 9, 2018
Studien: Sind NSAID und Allopurinol weniger gefährlich als angenommen?
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Published on October 9, 2018
Un medicamento para la gota puede proteger contra la enfermedad renal crónica
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Published on October 9, 2018
Allopurinol for Gout an Unlikely Contributor to Kidney Disease Progression
- Published on October 9, 2018