Ching-Ti Liu
Profiles

Ching-Ti Liu, PhD

Professor, Biostatistics - Boston University School of Public Health

ctliu@bu.edu

Biography

Dr. Liu's research interest mainly focuses on the development of statistical and computational approaches for genetics/genomics and bioinformatics studies. He also collaborates as a statistician or statistical geneticist on projects studying complex diseases such as diabetes, obesity, musculoskeletal disorder, and cancer. Dr. Liu has more than 10-year experience working on Framingham Heart Study (FHS) as a biostatistician collaborating on various projects. Dr. Liu has also functioned as a collaborator on traditional epidemiological, biomedical or basic science research beyond FHS. In addition, Dr. Liu has been actively engaged in several international collaborative consortia for the analysis of genetics and genomics data.

Other Positions

  • Investigator - Framingham Heart Study

Education

  • University of California, Los Angeles, PhD Field of Study: Statistics
  • University of California, Los Angeles, MS Field of Study: Statistics
  • National Central University, MS Field of Study: Statistics
  • National Central University, BS Field of Study: Statistics

Classes Taught

  • SPHBS723
  • SPHBS806

Publications

  • Published on 4/26/2026

    Zhang Y, Nguyen NQH, Hanson PA, Sevilla-Gonzalez M, Haessler J, Sarnowski C, Yao J, Yu B, Jamshidi A, Boerwinkle E, Brown MR, Chen ZZ, Ida Chen YD, Clish C, DiCorpo D, Durda P, Gerszten R, Goodarzi MO, Guo X, Heard-Costa NL, Johnson WC, Kooperberg C, Pankow JS, Post WS, Reiner AP, Rich SS, Rotter JI, de Vries PS, Wood AC, Taylor KD, Manning AK, Dupuis J, Meigs JB, Liu CT. Plasma metabolomic profiles associated with cardiovascular disease in type 2 diabetes from the Trans-Omics for Precision Medicine (TOPMed) program. Atherosclerosis. 2026 Apr 26; 417:120758. PMID: 42085744.

    Read At: PubMed
  • Published on 1/20/2026

    Yang T, Wang Y, Zhou Z, Liu CT. engGNN: A Dual-Graph Neural Network for Omics-Based Disease Classification and Feature Selection. ArXiv. 2026 Jan 20. PMID: 41647208.

    Read At: PubMed
  • Published on 1/14/2026

    Li J, Hu J, Yun H, Mei Z, Wang X, Luo K, Guasch-Ferré M, Han X, Truong B, Merino J, Jia C, Ruiz-Canela M, Rebholz CM, Moon EH, Alkis T, Liu G, Yao J, Zhang X, Porneala BC, Salas-Salvadó J, Wang TJ, Dupuis J, Selvin E, Guo X, Bhupathiraju SN, Brody JA, Liu Y, Wood AC, North KE, Jung SY, Liu CT, Sotoodehnia N, Liu S, Tinker LF, Eliassen AH, Manson JE, Florez JC, Gerszten RE, Clish CB, Liang L, Lemaitre RN, Tucker KL, Rich SS, Rotter JI, Martínez-González MA, Rexrode KM, Meigs JB, Boerwinkle E, Kaplan RC, Hu FB, Yu B, Qi Q. Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes. Nat Med. 2026 Feb; 32(2):660-670. PMID: 41535386.

    Read At: PubMed
  • Published on 1/10/2026

    Lee S, Miller CL, Bentley AR, Brown MR, Nagarajan P, Noordam R, Morrison JL, Schwander K, Westerman K, Kho M, Kraja AT, de Vries PS, Ammous F, Aschard H, Bartz TM, Do A, Dupont CT, Feitosa MF, Gudmundsdottir V, Guo X, Harris SE, Hikino K, Huang Z, Lefevre C, Lyytikäinen LP, Milaneschi Y, Nardone GG, Santin A, Schmidt H, Shen B, Sofer T, Sun Q, Tan YA, Tang J, Thériault S, van der Most PJ, Ware EB, Weiss S, Xing WY, Yu C, Zhao W, Ansari MAY, Anugu P, Attia JR, Bazzano LA, Bis JC, Breyer M, Cade B, Chen G, Collins S, Corley J, Davies G, Dörr M, Du J, Edwards TL, Faquih T, Faul JD, Fohner AE, Fretts AM, Gangireddy S, Gepner A, Graff M, Hofer E, Homuth G, Hood MM, Jie X, Kähönen M, Kardia SLR, Karvonen-Gutierrez CA, Launer LJ, Levy D, Maheshwari M, Martin LW, Matsuda K, McNeil JJ, Nolte IM, Okochi T, Raffield LM, Raitakari OT, Risch L, Risch M, Roux AD, Ruiz-Narvaez EA, Russ TC, Saito T, Schreiner PJ, Scott RJ, Shikany J, Smith JA, Snieder H, Spedicati B, Tai ES, Taylor AM, Taylor KD, Tesolin P, van Dam RM, Wang R, Wenbin W, Xie T, Yao J, Young KL, Zhang R, Zonderman AB, Concas MP, Conen D, Cox SR, Evans MK, Fox ER, de Las Fuentes L, Giri A, Girotto G, Grabe HJ, Gu C, Gudnason V, Harlow SD, Holliday E, Jost JB, Lacaze P, Lee S, Lehtimäki T, Li C, Liu CT, Morrison AC, North KE, Penninx BWJH, Peyser PA, Province MM, Psaty BM, Redline S, Rosendaal FR, Rotimi CN, Rotter JI, Schmidt R, Sim X, Terao C, Weir DR, Zhu X, Franceschini N, O'Connell JR, Jaquish CE, Wang H, Manning A, Munroe PB, Rao DC, Chen H, Gauderman WJ, Bierut LJ, Winkler TW, Fornage M. Large-scale blood pressure GWAS accounting for gene-depression interactions in 564,680 individuals from diverse populations. HGG Adv. 2026 Apr 09; 7(2):100566. PMID: 41520179.

    Read At: PubMed
  • Published on 1/9/2026

    Cuellar-Lobo M, Gao M, Ruda MM, Prescott B, Xanthakis V, Benjamin EJ, Cheng S, Vasan RS, Liu CT, Tsao CW. Association of Cardiovascular Health and Genetic Risk for Left Ventricular Mass with Left Ventricular Structure, Function, and Incident Cardiovascular Outcomes. medRxiv. 2026 Jan 09. PMID: 41542664.

    Read At: PubMed
  • Published on 12/9/2025

    Wang N, Zhang Y, Schroeder P, Huerta-Chagoya A, Mandla R, Meigs JB, Manning AK, Liu CT, Dupuis J, Mercader JM. Evaluation of Sex-Stratified Polygenic Risk Scores for Type 2 Diabetes Mellitus and Glycemic Traits in the Framingham Heart Study. Diabetes Metab J. 2025 Dec 09. PMID: 41360390.

    Read At: PubMed
  • Published on 11/26/2025

    Noordam R, Wang W, Nagarajan P, Wang H, Brown MR, Bentley AR, Hui Q, Kraja AT, Morrison JL, O'Connel JR, Lee S, Schwander K, Bartz TM, de Las Fuentes L, Feitosa MF, Guo X, Hanfei X, Harris SE, Huang Z, Kals M, Lefevre C, Mangino M, Milaneschi Y, van der Most PJ, Pacheco NL, Palmer ND, Rao V, Rauramaa R, Sun Q, Tabara Y, Vojinovic D, Wang Y, Weiss S, Yang Q, Zhao W, Zhu W, Ansari MAY, Aschard H, Anugu P, Assimes TL, Attia J, Baker LD, Ballantyne C, Bazzano L, Boerwinkle E, Cade B, Chen HH, Chen W, Ida Chen YD, Chen Z, Cho K, De Anda-Duran I, Dimitrov L, Do A, Edwards T, Faquih T, Hingorani A, Fisher-Hoch SP, Gaziano JM, Gharib SA, Giri A, Ghanbari M, Grabe HJ, Graff M, Charles Gu C, He J, Heikkinen S, Hixson J, Ho YL, Hood MM, Houghton SC, Karvonen-Gutierrez CA, Kawaguchi T, Kilpeläinen TO, Komulainen P, Lin HJ, Linchangco GV, Luik AI, Ma J, Meigs JB, McCormick JB, Menni C, Nolte IM, Norris JM, Petty LE, Polikowsky HG, Raffield LM, Rich SS, Riha RL, Russ TC, Ruiz-Narvaez EA, Sitlani CM, Smith JA, Snieder H, Sofer T, Shen B, Tang J, Taylor KD, Teder-Laving M, Triatin R, Tsai MY, Völzke H, Westerman KE, Xia R, Yao J, Young KL, Zhang R, Zonderman AB, Zhu X, Below JE, Cox SR, Evans M, Fornage M, Fox ER, Franceschini N, Harlow SD, Holliday E, Ikram MA, Kelly T, Lakka TA, Lawlor DA, Li C, Liu CT, Mägi R, Manning AK, Matsuda F, Morrison AC, Nauck M, North KE, Penninx BW, Province MA, Psaty BM, Rotter JI, Spector TD, Wagenknecht LE, van Dijk KW, Jaquish CE, Wilson PW, Peyser PA, Munroe PB, de Vries PS, Gauderman WJ, Sun YV, Chen H, Miller CL, Winkler TW, Rao DC, Redline S, van Heemst D. Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participants. Atherosclerosis. 2026 Jan; 412:120603. PMID: 41325697.

    Read At: PubMed
  • Published on 11/1/2025

    Haff MG, Murabito JM, Vasan RS, Spartano NL, Liu CT, Zhang X, Benjamin EJ, Lewis GD, Long MT. Physical Activity by Accelerometer Inversely Associated With Liver Fibrosis; Cross-Sectional Analysis of a Longitudinal Cohort. Liver Int. 2025 Nov; 45(11):e70380. PMID: 41055309.

    Read At: PubMed
  • Published on 10/30/2025

    Xu C, Bhurosy T, Liu CT, Lee YH. Ten-year dietary trends and urban-rural disparities in fruit, vegetable, meat, egg, and milk products consumption among older Chinese adults. Nutr Diet. 2026 Apr; 83(2):267-280. PMID: 41164909.

    Read At: PubMed
  • Published on 10/7/2025

    Zhang M, Brown MR, Bentley AR, Winkler TW, Noordam R, Nagarajan P, Guo B, Lee S, Schwander K, Wang W, Westerman K, O'Connell JR, Ammous F, Argoty-Pantoja AD, Bartz TM, Batini C, Boua PR, Cordell HJ, Díez-Ahijado L, Dimitrov L, Do AN, Du J, Feitosa MF, Giri A, Giulianini F, Gudmundsdottir V, Guo X, Harris SE, Hasbani NR, Herold JM, Hikino K, Hofer E, Hsu FC, Jackson AU, Kho M, Kraja AT, Lyytikäinen LP, Meirhaeghe A, Muntaner M, Nakatochi M, Nardone GG, Nutile T, Palmer ND, Pecori A, Rao VS, Rauramaa R, Sanghvi MM, Santin A, Shen B, Stringham HM, Takeuchi F, Tan YA, Tang J, Thériault S, Trofimova O, Trompet S, van der Most PJ, Wang YX, Wang Z, Wang Y, Ware EB, Weiss S, Wickremasinghe AR, Yu C, Zhu W, Ansari MAY, Anugu P, Banas B, Barr RG, Basnet TB, Boerwinkle E, Böger CA, Breyer M, Broeckel U, Bryant L, Cade B, Camarda S, Cennamo P, Checkley W, Chee ML, Chen G, Coley K, Collins SD, de Borst MH, de Las Fuentes L, Deary IJ, Dupont CT, Enzinger C, Faquih T, Faul JD, Silva LF, Gauthier V, Gepner AD, Gorski M, Grabe HJ, Graff M, Gu CC, He J, Heikkinen S, Hidalgo B, Highland HM, Hixson JE, Hood MM, Hunt SC, Irvin MR, Isono M, Kähönen M, Kardia SLR, Karvonen-Gutierrez CA, Kasturiratne A, Katsuya T, Kaufman JD, Koistinen HA, Komulainen P, Krämer BK, Launer LJ, Leonard H, Levy D, Liu J, Marques-Vidal P, Martinez-Perez A, Matsuda K, McNeil JJ, Milaneschi Y, Miranda JJ, Morrison JL, Nalls M, Ng MC, Nolte IM, Norris JM, Oravilahti A, Patki A, Petty LE, Peyser PA, Pianigiani G, Raffield LM, Raitakari OT, Ramsay M, Rice KM, Ridker PM, Risch L, Risch M, Ruggiero D, Ruiz-Narvaez EA, Russ TC, Sabanayagam C, Vaitinadin NS, Schmidt R, Scott LJ, Singh S, Sitlani CM, Smit RAJ, Smith JA, Sun Q, Tai ES, Taylor KD, Tesolin P, Tham YC, Tinashe C, van Dam RM, Vaucher J, Völker U, Wang C, Wilson OD, Wong TY, Xu J, Yamamoto K, Yao J, Yokota M, Young KL, Zimmermann ME, Amouyel P, Below JE, Bergmann S, Bernabe-Ortiz A, Bierut L, Boehnke M, Bowden DW, Brandenburg JT, Chasman DI, Cheng CY, Ciullo M, Concas MP, Conen D, Cox SR, Dauchet L, de Silva HJ, Dörr M, Edwards TL, Fox ER, Franceschini N, Freedman BI, Girotto G, Gudnason V, Harlow SD, Heid IM, Hung AM, Ichihara S, Jaquish CE, John C, Jonas JB, Jukema JW, Kato N, Keavney BD, Kelly TN, Laakso M, Lacaze P, Lakka T, Lee S, Lehtimäki T, Liu CT, Loos RJF, North KE, Penninx B, Province MA, Psaty BM, Redline S, Rosendaal FR, Rotimi CN, Rotter JI, Sabater-Lleal M, Schmidt H, Sim X, Snieder H, Spedicati B, Stark KJ, Terao C, Wagenknecht LE, Weir DR, Zhao W, Zhu X, Munroe PB, Sun YV, Gauderman J, Manning AK, Fornage M, Aschard H, Wang H, de Vries PS, Wang G, Rao DC, Morrison AC, Chen H. Large-Scale Gene-Smoking Interactions and Fine Mapping Study Identifies Multiple Novel Blood Pressure Loci in over 1 Million Individuals. medRxiv. 2025 Oct 07. PMID: 41480028.

    Read At: PubMed

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