Jayandra Himali
Profiles

Jayandra Jung Himali, PhD

Adjunct Associate Professor, Neurology - Boston University Chobanian & Avedisian School of Medicine

(617) 638-5139
Crosstown Center
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Biography

Jayandra Jung Himali, PhD, serves as an adjunct Associate Professor of Neurology and Biostatistics at Boston University Schools of Medicine and of Public Health, and a Center Faculty Member of the Framingham Heart Study (FHS). He has been engaged in collaborative public health research and teaching for over a decade. As a senior Biostatistician at the Neurology core of FHS, his research efforts are focused on the interrelated areas of: (1) the epidemiology of dementia and Alzheimer’s disease (AD) and relating traditional and novel biomarkers to the risk of dementia and AD; (2) the epidemiology of stroke and vascular cognitive impairment; (3) understanding vascular contributions to cognitive impairment and dementia including AD; and (4) investigating the role of modifiable lifestyle factors: sleep, diet and physical activity on the incidence of dementia, cognitive decline and MRI-defined brain aging. His research is also focused on outcome assessment in Epilepsy, Parkinson’s disease, and neuropathology. He has received the Nepal Bidhya Bhusan Class ‘A’ Medal from the government of Nepal for highest academic achievement in doctoral studies.

Other Positions

  • Investigator - Framingham Heart Study

Education

  • Boston University School of Public Health, PhD Field of Study: Biostatistics
  • Tribhuvan University, MSc Field of Study: Statistics
  • Tribhuvan University, BSc Field of Study: Statistics

Websites

Publications

  • Published on 9/9/2025

    Yiallourou S, Baril AA, Wiedner C, Misialek JR, Kline CE, Harrison S, Cannon E, Yang Q, Bernal R, Bisson A, Himali D, Cavuoto M, Weihs A, Beiser A, Gottesman RF, Leng Y, Lopez O, Lutsey PL, Purcell SM, Redline S, Seshadri S, Stone KL, Yaffe K, Ancoli-Israel S, Xiao Q, Vaou EO, Himali JJ, Pase MP. Sleep architecture and dementia risk in adults: an analysis of 5 cohorts from the Sleep and Dementia Consortium. Sleep. 2025 Sep 09; 48(9). PMID: 40377976.

     Read At: PubMed
  • Published on 8/21/2025

    Araujo-Contreras R, Pinheiro AA, Ekenze O, Sisto J, Aparicio HJ, Beiser A, Himali JJ, Lioutas V, DeCarli C, Seshadri S, Demissie S, Romero JR. Multi-marker cerebral small vessel disease score and risk of incident depression: The Framingham Heart Study. J Affect Disord. 2025 Aug 21; 392:120089. PMID: 40848767.

     Read At: PubMed
  • Published on 8/7/2025

    Duan D, Jun JC, Johnson DA, Ahima RS, Himali JJ, Bertoni AG, Redline S, Echouffo-Tcheugui JB. Associations of Sleep Health and Metabolic Syndrome Severity in Black Individuals: The Jackson Heart Sleep Study. J Clin Endocrinol Metab. 2025 Aug 07; 110(9):e2864-e2870. PMID: 40339134.

     Read At: PubMed
  • Published on 8/5/2025

    Chakkarai S, Sadowski M, Yang Q, Ray A, Wang R, Thomas LF, Fuentes RP, Tabar MS, Cui B, Jian X, Nyquist PA, Gill D, Aiello AE, Montine TJ, Bukhari S, Rogalski E, Edland SE, Haan ME, Kawas CH, Corrada MM, Salardini A, Chen ZZ, Himali JJ, Satizabal CL, Gerszten RE, Åsvold BO, Fornage M, Cruchaga C, Habes M, Chasman DI, Launer LJ, Flanagan ME, Brumpton BM, Georgakis MK, Zaitlen N, Ruiz A, Debette S, Seshadri S, Sargurupremraj M. Cross-tissue omics-guided drug repurposing triangulates novel targetable mechanisms for Alzheimer's disease and candidate genetic biomarkers for treatment stratification. Res Sq. 2025 Aug 05. PMID: 40799764.

     Read At: PubMed
  • Published on 7/31/2025

    Wadop YN, Bernal R, Njamnshi WY, Satizabal CL, Beiser A, Ruiz A, Njamnshi AK, Vasan RS, Seshadri S, Himali JJ, Fongang B. Altered Gut Microbiota Mediates the Association between APOE Genotype and Amyloid-ß Accumulation in Middle-Aged Adults. bioRxiv. 2025 Jul 31. PMID: 40766561.

     Read At: PubMed
  • Published on 7/11/2025

    Teixeira AL, de Miranda AS, Venna VR, Himali JJ, Bauer ME. Understanding late-life depression: focus on inflammation. Curr Opin Psychiatry. 2025 Sep 01; 38(5):376-382. PMID: 40709634.

     Read At: PubMed
  • Published on 7/5/2025

    Full KM, Pusalavidyasagar SS, Palta P, Hicks CW, Spira AP, Windham BG, Juraschek SP, Pase MP, Himali JJ, Lutsey PL. Late-life sleep medication use associated with increased falls risk in the Atherosclerosis Risk in Communities (ARIC) study. Sleep Health. 2025 Oct; 11(5):746-753. PMID: 40619283.

     Read At: PubMed
  • Published on 7/3/2025

    Lioutas VA, Peloso G, Romero JR, Aparicio H, Gonzales M, Werry A, Himali D, Himali J, Banerjee A, Gosh S, Ramachandran VS, Beiser A, Seshadri S. Long-Term Incidence of Dementia Following Transient Ischemic Attack: A Longitudinal Cohort Study. J Am Heart Assoc. 2025 Jul 15; 14(14):e037817. PMID: 40611491.

     Read At: PubMed
  • Published on 4/1/2025

    Young VM, Bernal R, Baril AA, Zeynoun J, Wiedner C, Gaona C, Beiser A, Teixeira AL, Salardini A, Pase MP, Himali JJ, Seshadri S. Long sleep duration, cognitive performance, and the moderating role of depression: A cross-sectional analysis in the Framingham Heart Study. Alzheimers Dement. 2025 Apr; 21(4):e70160. PMID: 40257009.

     Read At: PubMed
  • Published on 4/1/2025

    Salardini A, Himali JJ, Abdullah MS, Chaudhari R, Young V, Zilli EM, McGrath ER, Gonzales MM, Thibault EG, Salinas J, Aparicio HJ, Himali D, Ghosh S, Buckley RF, Satizabal CL, Johnson KA, DeCarli C, Fakhri GE, Vasan RS, Beiser AS, Seshadri S. Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study. Alzheimers Dement. 2025 Apr; 21(4):e70179. PMID: 40271551.

     Read At: PubMed

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