Computational Modeling and Data Sciences
Groundbreaking technological advances in recent decades have enabled unprecedented access to biological systems at multiple length and time scales, resulting in an explosion of data. This information holds the key to unraveling fundamental principles governing biological systems, engineering novel bio-inspired systems, and repairing systems that have been rendered dysfunctional by age or disease. With this promise comes a tremendous challenge: to distill and transform overwhelming amounts of information into knowledge that can improve human health and society. BU BME computational modeling and data science faculty apply rigorous quantitative and engineering methods to a tremendous variety of biological systems across length and time scales to seize this challenge.
We process large-scale data sets from genomic, molecular, neural, and other systems. To make sense of these data, we employ quantitative frameworks from artificial intelligence, data science, statistics, and signal processing. We construct computational models to understand normal physiological function and dysfunction in diseases, including cancer, diabetes, sensory impairments, and lung disease. Our work bridges length scales from the protein to the whole organ. Finally, we design and engineer novel bioinspired systems, including biosensors, wearables, and brain-inspired algorithms, for a wide-range of applications in health and society.
Computational Modeling and Data Sciences Faculty
Primary Faculty: David Boas, Charles Delisi, Mary Dunlop, Michael Economo, James Galagan, Xue Han, Simon Kasif, Laura Lewis, Hadi T. Nia, Kamal Sen, Allyson Sgro, Bela Suki, Lucia Vaina, Sandor Vajda, John White
Emeritus: Steve Colburn, Stephen Grossberg, Temple Smith, Malvin Teich
Affiliated Research Centers
- Biomolecular Engineering Research Center (BMERC)
- Center for Systems Neuroscience
- Neurophotonics Center
- Photonics Center
- Rajen Kilachand Center for Integrated Life Sciences & Engineering
- Precision Diagnostics Center.
BME Computational Modeling and Data Sciences in the news:
By Caroline Amato An article by a BU team entitled “Non-genetic Photoacoustic Stimulation of Single Neurons” will appear in Light: Science & Applications. This research is led by Professors Chen Yang (ECE, Chem, MSE) and Ji-Xin Cheng (ECE, BME, MSE) in collaboration with Professor John White (BME) and Professor Heng-Ye Man... More
Continuing a streak of honors for her ground-breaking research into the complex neural circuits that govern sleep, Assistant Professor Laura Lewis (BME) has been selected one of 22 early-career researchers to join the Pew Scholars Program. More
By Caroline Amato BU researchers reported an ultrafast fingerprint-stimulated Raman spectroscopic imaging platform, with broad applications to cancer metabolism, brain mapping, and biofuel production, in Nature Communications on May 24th, 2021. This work was funded by grants from the Department of Energy and the NIH. ECE Professors Ji-Xin Cheng and Lei Tian... More
Professor Yannis Paschalidis (ECE, BME, SE) discussed data-driven reasoning—which he calls “the backbone of engineering systems”—and predictive health analytics as he delivered the Charles DeLisi Distinguished Lecture May 6 to an online audience of about 100 members of the Boston University community. The DeLisi Award and Lecture honors a senior faculty... More
by Allison Kleber How does learning a new skill or process change the physical structure of the brain? Using techniques from data science and high-dimensional statistics, Professors Bobak Nazer (ECE), Venkatesh Saligrama (ECE, SE), and Xue Han (BME), aim to find out. Their project, titled “Discovering Changes in Networks: Fundamental Limits, More
Three ENG faculty members have been elected to the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE): Associate Professor Doug Densmore (ECE, BME), Associate Professor Mo Khalil (BME), and Professor Katherine Zhang (ME, BME, MSE). More
The award funding will further the biomedical engineer's research on brain function By Jessica Colarossi Laura Lewis (BME) has been awarded a 2021 Sloan Research Fellowship, one of the most prestigious awards for early-career scientists. Lewis and BU computer scientist Alina Ene are two of 126 fellows chosen this year, and... More
As one of only three winners worldwide, Assistant Professor Laura Lewis was selected for the inaugural award for early career research in neuroscience. More
ENG alumnus Malek Sukkar (MFG ’92) has established the College’s first endowed professorship. More
Assistant Professor Hadi Nia has published a first-authored review paper in SCIENCE on the physical traits of cancer. More