Vanessa Xanthakis, PhD
Associate Professor, Biostatistics - Boston University School of Public Health
Biography
Dr. Vanessa Xanthakis is a biostatistician with training in applied mathematics and statistics, and has a strong commitment to clinical epidemiological research. Presently, she is an Assistant Professor in the Section of Preventive Medicine and Epidemiology in the Department of Medicine at Chobanian and Avedisian School of Medicine and in the Biostatistics Department at Boston University School of Public Health. She is an investigator at the Framingham Heart Study and serves as the biostatistician on several investigations. She also serves as the Program Director for the Boston University T32 Program in Cardiovascular Epidemiology and the Promotion of Research In MEdical Residency (R38) program. She is the Director of Research Training for the Section of Preventive Medicine and Epidemiology. For the last 12 years, Dr. Xanthakis has focused her research on:
A) the epidemiology of cardiac remodeling and subclinical disease, including identifying cardiovascular disease risk factors;
B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function;
C) epidemiology of novel biomarkers including but not limited to natriuretic peptides, adipokines, and vascular growth factors;
D) cardiovascular risk prediction using biomarkers and assessing their incremental prognostic utility (focus of her PhD thesis);
E) epidemiology of heart failure and its precursors; and
F) ideal cardiovascular health and its impact on cardiovascular disease and its precursors.
Other Positions
- Associate Professor, Medicine - Boston University Chobanian & Avedisian School of Medicine
- Investigator - Framingham Heart Study
- Member, Evans Center for Interdisciplinary Biomedical Research - Boston University
Education
- Boston University School of Public Health, PhD Field of Study: Biostatistics
- University of Athens, MS Field of Study: Applied Mathematics
- University of Athens, BS Field of Study: Applied Mathematics
Publications
- Published on 4/27/2026
Plante TB, Sun Y, Balte PP, Lloyd-Jones D, Ning H, Allen N, Mongraw-Chaffin M, Pettee Gabriel K, Xanthakis V, Norwood AF, Gonzalez S, Sotres-Alvarez D, Talavera GA, Daviglus ML, Talegawkar SA, Kandula N, Elkind MSV, Rundek T, Gutierrez J, Levitan EB, Cushman M, Judd SE, Wang HE, Zakai NA, Howard VJ, Pamir N, Safford MM, Kamin Mukaz D, Fretts AM, Juraschek SP, Oelsner EC. Life's Essential 8 and Risk of Severe COVID-19 Among Adults Without Clinical Cardiovascular Disease: The C4R Study. J Am Heart Assoc. 2026 Apr 27; e048256. PMID: 42037457.
Read At: PubMed
- Published on 4/23/2026
Qian F, Gajjar P, Prescott B, Mitchell GF, Xanthakis V, Rade JJ, Nayor M. Modifiable Correlates With Systemic Thromboxane Generation and Association With Cardiovascular Outcomes: Results From the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2026 Jun; 46(6):e324561. PMID: 42021731.
Read At: PubMed
- Published on 4/17/2026
Campos A, Liu T, Prescott B, Ma J, Haff MG, Walker ME, Mohanty A, Xanthakis V. Association of Life's Essential 8 with Hepatic Fibrosis, MASLD, and MetALD in the Framingham Heart Study. Nutrients. 2026 Apr 17; 18(8). PMID: 42075086.
Read At: PubMed
- Published on 4/16/2026
Xanthakis V, Prescott B, Ning H, Krishnan V, Lloyd-Jones DM. Relating Cumulative Life's Essential 8 Score With Cardiovascular Disease and Death: The Framingham Heart Study. JACC Adv. 2026 May; 5(5):102706. PMID: 41996786.
Read At: PubMed
- Published on 4/4/2026
Alexandrou M, Parikh NI, Brilakis ES, Lloyd-Jones DM, Xanthakis V. Insights Into Cardiovascular Disease in Women From the Framingham Heart Study. JACC Adv. 2026 Apr 04; 102722. PMID: 41999366.
Read At: PubMed
- Published on 3/19/2026
Korzinski TJ, Prescott BR, Hamel-Sellman DJ, Xanthakis V, Cooper LL, Hamburg NM, Tsao CW, Benjamin EJ, Vasan RS, Mitchell GF. Development and Validation of the AI-HeartAge Model in Framingham and UK Biobank. Hypertension. 2026 Jun; 83(6):e26209. PMID: 41853838.
Read At: PubMed
- Published on 3/11/2026
Pan S, Vasan RS, Beiser AS, Seshadri S, Xanthakis V. Associations of Left Atrial Dimension and Ventricular Mass With Long-Term Health Outcomes: Framingham Heart Study. JACC Adv. 2026 Apr; 5(4):102643. PMID: 41819678.
Read At: PubMed
- Published on 2/12/2026
Davis DN, Gajjar P, Xanthakis V, Lloyd-Jones D, Nayor M. Refined Heart Failure Stages Incorporating Cardiorespiratory Fitness Are Differentially Associated With Heart Failure Risk in the Community. J Am Heart Assoc. 2026 Feb 17; 15(4):e045791. PMID: 41676947.
Read At: PubMed
- Published on 2/4/2026
Gauen AM, Petito LC, Zhang Y, Zhou H, Zhou M, Xia M, Fang M, Reynolds K, Xanthakis V, Safford M, Colantonio LD, Rana JS, Bellows BK, Moran AE, Huang X, Shah NS, Allen NB, An J. PREVENT Equations in Young Adults: Fairness, Calibration, and Performance Across Racial and Ethnic Groups. J Am Coll Cardiol. 2026 Feb 04. PMID: 41636665.
Read At: PubMed
- Published on 1/9/2026
Cuellar-Lobo M, Gao M, Ruda MM, Prescott B, Xanthakis V, Benjamin EJ, Cheng S, Vasan RS, Liu CT, Tsao CW. Association of Cardiovascular Health and Genetic Risk for Left Ventricular Mass with Left Ventricular Structure, Function, and Incident Cardiovascular Outcomes. medRxiv. 2026 Jan 09. PMID: 41542664.
Read At: PubMed
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News & In the Media
- Published on July 20, 2020