Leonardo Martinez
Profiles

Leonardo Martinez

Assistant Professor, Epidemiology - Boston University School of Public Health

Biography

Leo Martinez joined the Department of Epidemiology at Boston University in 2021. He completed his doctorate in epidemiology at the University of Georgia and a postdoctoral fellowship at Stanford University School of Medicine.

Dr. Martinez uses epidemiological and quantitative approaches to study early-life risk factors for pediatric tuberculosis in high-burden settings, tuberculosis transmission dynamics in high-risk populations (e.g., prisoners, persons living with HIV or diabetes), and the relationship between tuberculosis and non-communicable diseases.

Dr. Martinez's lab is currently working with colleagues and collaborators in South Africa, China, Brazil, Paraguay, Uganda, and the United Kingdom. We believe that collaboration across professional disciplines, backgrounds, and perspectives is the key to solving intractable health issues and the lab welcomes discussions with others working on these same health issues.

Dr. Martinez is an International Advisory Board member of the The Lancet Child & Adolescent Health and serves as an academic editor and Editorial Board member for two journals, PLOS Global Public Health and the Journal of Tuberculosis and Lung Disease.

Dr. Martinez has published manuscripts in clinical and epidemiological journals such as The Lancet, The Lancet Respiratory Medicine, The Lancet Global Health, The Lancet Child & Adolescent Health, The Lancet Public Health, the American Journal of Respiratory Care & Critical Medicine, the European Respiratory Journal, JAMA Internal Medicine, Clinical Infectious Diseases, the American Journal of Epidemiology, amongst others. A list of major publications is listed below but a full list can be seen in the publications tab on this profile page.

Selected Publications:

Martinez L, Nicol MP, Wedderburn C, Stadler A, Botha M, Workman L, le Roux DM, Zar HJ (2021). Cytomegalovirus Acquisition in Infancy and the Risk of Tuberculosis in Childhood: A Longitudinal Birth Cohort in Cape Town, South Africa. The Lancet Global Health. 9 (12), e1740-e1749. (IF: 26.8).

Ge Y†, Martinez L†, Sun S, Chen Z, Zhang F, Li F, Sun W, Chen E, Pan J, Li C, Sun J, Handel A, Ling F, Shen Y (2021). Covid-19 transmission dynamics among close contacts of Covid-19 index cases: a population-based cohort study in Zhejiang Province, China. JAMA Internal Medicine. 181 (10): 1343-1350. (IF: 21.9) (†Co-first).

Martinez L, Cords O, Horsburgh CR, Andrews JR, Pediatric TB Contact Studies Consortium (2020). The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis. The Lancet. 395, 973-984. (IF: 79.3)

Walter K†, Martinez L†, Arakaki-Sanchez D, Sequera G, Estigarribia G, Cohen T, Ko A, García-Basteiro A, Rueda ZV, Lopez Olarte R, Espinal M, Croda J, Andrews JR (2021). The escalating tuberculosis crisis in Central and South American prisons. The Lancet. 397 (10284): 1591-1596. (IF: 79.3). (†Co-first).

Martinez L, Shen Y, Handel A, Chakraburty S, Stein C, Malone L, Boom WB, Quinn FD, Joloba ML, Whalen CC, Zalwango S (2018). Effectiveness of WHO’s Pragmatic Screening Algorithm for Child Contacts of Tuberculosis Cases in Resource-Constrained Settings: A Prospective Cohort Study in Uganda. The Lancet Respiratory Medicine. 6 (4), 276–286. (IF: 30.7)

Cords O†, Martinez L†, Warren J, O'Marr JM, Walter KS, Cohen T, Zheng J, Ko AI, Croda J, Andrews JR. Incidence and Prevalence of Tuberculosis in Incarcerated Populations: A Systematic Review and Meta-analysis (2021). The Lancet Public Health. 6 (5): e300-e308. (IF: 21.648). (†Co-first).

Liu Q, You N, Lu F, Pan H, Lu P, Wang J, Lu W, Zhu L, Martinez L (2021). Glycemic trajectories and treatment outcomes of new tuberculosis patients: a prospective study in Eastern China. American Journal of Respiratory and Critical Care Medicine. 204 (3): 347-356. (IF: 21.405)

Martinez L, Lo N, Cords O, Hill PC, Khan P, Hatherill M, Mandalakas A, Kay A, Croda J, Horsburgh CR, Zar HJ, Andrews JR (2019). Paediatric Tuberculosis Transmission Outside the Household: Challenging Historical Paradigms to Inform Future Public Health Strategies. The Lancet Respiratory Medicine, 7 (6), 544-552. (Co-first). (IF: 30.7)

Martinez L, le Roux DM, Barnett W, Nicol MP, Zar HJ (2018). Tuberculin Skin Test Conversion and Primary Progressive Tuberculosis Disease in the First Five Years of Life: A Birth Cohort Study from Cape Town, South Africa. The Lancet Child & Adolescent Health. 2(1), 46–55. (IF: 11.3)

Liu Q, Lu P, Shen Y, Li C, Wang K, Zhu L, Lu W, Martinez L (2020). Collateral Impact of the Covid-19 Pandemic on Tuberculosis Control in Jiangsu Province, China. Clinical Infectious Diseases. 73 (3): 542-544. (IF: 9.1)

Martinez L, Sekandi JN, Castellanos ME, Zalwango S, Whalen CC (2016). Infectiousness of HIV-seropositive Patients with Tuberculosis in a High-burden African Setting. The American Journal of Respiratory and Critical Care Medicine. 194 (9), 1152–1163. (IF: 21.6)

Martinez L, Verma R, Croda J, Horsburgh CR, Walter KS, Degner N, Middelkoop K, Koch A, Hermans S, Warner D, Wood R, Cobelens F, Andrews JR (2019). Detection, Survival, and Infectious Potential of Mycobacterium tuberculosis in the Environment: A Review of the Evidence and Epidemiological Implications. European Respiratory Journal, 27; 53 (6). (IF: 12.2)

Martinez L, Woldu H, Chen C, Castellanos ME, Lu P, Liu Q, Whalen CC, Zhu L (2021). Transmission Dynamics in Tuberculosis Patients with Human Immunodeficiency Virus: A Systematic Review and Meta-Analysis of 32 Observational Studies. Clinical Infectious Diseases. 73 (9): e3446-e3455. (IF: 9.1).

Martinez L, Shen Y, Mupere E, Kizza A, Hill PC, Whalen CC (2017). Transmission of Mycobacterium tuberculosis in Households and the Community: A Systematic Review and Meta-Analysis. American Journal of Epidemiology. 185 (12), 1327–1339. (IF: 5.4)

Publications

  • Published on 4/7/2022

    Li Y, Kong Y, Ebell MH, Martinez L, Cai X, Lennon RP, Tarn DM, Mainous AG, Zgierska AE, Barrett B, Tuan WJ, Maloy K, Goyal M, Krist AH, Gal TS, Sung MH, Li C, Jin Y, Shen Y. Development and Validation of a Two-Step Predictive Risk Stratification Model for Coronavirus Disease 2019 In-hospital Mortality: A Multicenter Retrospective Cohort Study. Front Med (Lausanne). 2022; 9:827261. PMID: 35463024.

    Read At: PubMed
  • Published on 3/1/2022

    Xu M, Lu W, Li T, Li J, Du W, Wu Q, Liu Q, Yuan B, Lu J, Ding X, Li F, Liu M, Chen B, Pu J, Zhang R, Xi X, Zhou R, Mei Z, Du R, Tao L, Martinez L, Lu S, Wang G, Zhu F. Sensitivity, Specificity, and Safety of a Novel ESAT6-CFP10 Skin Test for Tuberculosis Infection in China: 2 Randomized, Self-Controlled, Parallel-Group Phase 2b Trials. Clin Infect Dis. 2022 03 01; 74(4):668-677. PMID: 34021314.

    Read At: PubMed
  • Published on 2/1/2022

    Fennelly KP, Martinez L, Mandalakas AM. Tuberculosis: First in Flight. Am J Respir Crit Care Med. 2022 02 01; 205(3):272-274. PMID: 34905703.

    Read At: PubMed
  • Published on 12/1/2021

    Martinez L, Nicol MP, Wedderburn CJ, Stadler A, Botha M, Workman L, le Roux DM, Zar HJ. Cytomegalovirus acquisition in infancy and the risk of tuberculosis disease in childhood: a longitudinal birth cohort study in Cape Town, South Africa. Lancet Glob Health. 2021 12; 9(12):e1740-e1749. PMID: 34798032.

    Read At: PubMed
  • Published on 11/2/2021

    Martinez L, Woldu H, Chen C, Hallowell BD, Castellanos ME, Lu P, Liu Q, Whalen CC, Zhu L. Transmission Dynamics in Tuberculosis Patients With Human Immunodeficiency Virus: A Systematic Review and Meta-analysis of 32 Observational Studies. Clin Infect Dis. 2021 11 02; 73(9):e3446-e3455. PMID: 32770236.

    Read At: PubMed
  • Published on 11/2/2021

    Martinez L, Andrews JR. Identifying Priorities for Testing and Treatment of Latent Tuberculosis Infection in the United States. Clin Infect Dis. 2021 11 02; 73(9):e3483-e3485. PMID: 32588882.

    Read At: PubMed
  • Published on 10/28/2021

    Dos Santos PCP, da Silva Santos A, de Oliveira RD, da Silva BO, Soares TR, Martinez L, Andrews JR, Croda J. Pooling Sputum Samples for Efficient Mass Tuberculosis Screening in Prisons. Clin Infect Dis. 2021 Oct 28. PMID: 34718459.

    Read At: PubMed
  • Published on 10/1/2021

    Ge Y, Martinez L, Sun S, Chen Z, Zhang F, Li F, Sun W, Chen E, Pan J, Li C, Sun J, Handel A, Ling F, Shen Y. COVID-19 Transmission Dynamics Among Close Contacts of Index Patients With COVID-19: A Population-Based Cohort Study in Zhejiang Province, China. JAMA Intern Med. 2021 10 01; 181(10):1343-1350. PMID: 34424260.

    Read At: PubMed
  • Published on 8/26/2021

    Martinez L, Ncayiyana JR, Goddard L, Botha M, Workman L, Burd T, Myer L, Nicol M, Zar HJ. Vitamin D concentrations in infancy and the risk of tuberculosis in childhood: A prospective birth cohort in Cape Town, South Africa. Clin Infect Dis. 2021 Aug 26. PMID: 34436538.

    Read At: PubMed
  • Published on 8/2/2021

    Liu Q, Lu P, Shen Y, Li C, Wang J, Zhu L, Lu W, Martinez L. Collateral Impact of the Coronavirus Disease 2019 (COVID-19) Pandemic on Tuberculosis Control in Jiangsu Province, China. Clin Infect Dis. 2021 08 02; 73(3):542-544. PMID: 32857838.

    Read At: PubMed

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