Krista Francine Huybrechts, PhD
Adjunct Assistant Professor, Epidemiology - Boston University School of Public Health
Biography
Krista F. Huybrechts, M.S., Ph.D. is an Associate Professor of Medicine at Harvard Medical School and an epidemiologist in the Division of Pharmacoepidemiology and Pharmacoeconomics at the Brigham and Women’s Hospital. She also holds an appointment as adjunct Assistant Professor of Epidemiology at Boston University School of Public Health. Her research centers on the utilization, comparative safety and effectiveness of prescription medications in pregnant women and their offspring, and on studying the outcomes of medications for mental health disorders in vulnerable populations. She also has a special interest in research methodology and innovative research applications in relation to both these fields of study. She currently serves on the Board of Directors of the International Society of Pharmacoepidemiology and Therapeutic Risk Management and is a member of FDA’s Drug Safety and Risk Management Advisory Committee.
Her research centers on the utilization, comparative safety and effectiveness of prescription medications in pregnant women and their offspring (www.harvardpreg.org), and on studying the outcomes of medications for mental health disorders in vulnerable populations. She also has a special interest in research methodology and innovative research applications in relation to both these fields of study.
Dr. Huybrechts graduated magna cum laude with a Master of Science degree in Economics from the University of Antwerp, Belgium where she also worked as a researcher in health economics. Prior to completing a doctoral degree in epidemiology at Boston University School of Public Health, Dr. Huybrechts held several positions in pharmacoeconomics and outcomes research, both in Europe and the US. Her research projects focused primarily on psychiatry and neurology, and covered a broad spectrum of research designs, including clinical trials, naturalistic studies, retrospective data analyses, and decision-analytic simulation models.
Education
- Boston University School of Public Health, PhD Field of Study: Epidemiology
- University of Antwerp, MS Field of Study: Economics
- University of Antwerp, BS Field of Study: Economics
Publications
- Published on 5/1/2024
Suarez EA, Bateman BT, Hernandez-Diaz S, Straub L, McDougle CJ, Wisner KL, Gray KJ, Pennell PB, Lester B, Zhu Y, Mogun H, Huybrechts KF. Prescription Stimulant Use During Pregnancy and Risk of Neurodevelopmental Disorders in Children. JAMA Psychiatry. 2024 May 01; 81(5):477-488. PMID: 38265792.
Read At: PubMed
- Published on 4/6/2024
Chiu YH, Huybrechts KF, Zhu Y, Straub L, Bateman BT, Logan R, Hernández-Díaz S. Internal validation of gestational age estimation algorithms in healthcare databases using pregnancies conceived with fertility procedures. Am J Epidemiol. 2024 Apr 06. PMID: 38583933.
Read At: PubMed
- Published on 3/21/2024
Hernández-Díaz S, Straub L, Bateman BT, Zhu Y, Mogun H, Wisner KL, Gray KJ, Lester B, McDougle CJ, DiCesare E, Pennell PB, Huybrechts KF. Risk of Autism after Prenatal Topiramate, Valproate, or Lamotrigine Exposure. N Engl J Med. 2024 Mar 21; 390(12):1069-1079. PMID: 38507750.
Read At: PubMed
- Published on 3/1/2024
Suarez EA, Bateman BT, Straub L, Hernández-Díaz S, Jones HE, Gray KJ, Connery HS, Davis JM, Lester B, Terplan M, Zhu Y, Vine SM, Mogun H, Huybrechts KF. First Trimester Use of Buprenorphine or Methadone and the Risk of Congenital Malformations. JAMA Intern Med. 2024 Mar 01; 184(3):242-251. PMID: 38252426.
Read At: PubMed
- Published on 2/1/2024
Cesta CE, Rotem R, Bateman BT, Chodick G, Cohen JM, Furu K, Gissler M, Huybrechts KF, Kjerpeseth LJ, Leinonen MK, Pazzagli L, Zoega H, Seely EW, Patorno E, Hernández-Díaz S. Safety of GLP-1 Receptor Agonists and Other Second-Line Antidiabetics in Early Pregnancy. JAMA Intern Med. 2024 Feb 01; 184(2):144-152. PMID: 38079178.
Read At: PubMed
- Published on 1/24/2024
Brown JP, Yland J JJ, Williams PL, Huybrechts KF, Hernández-Díaz S. Accounting for Twins and Other Multiple Births in Perinatal Studies Conducted Using Healthcare Administration Data. medRxiv. 2024 Jan 24. PMID: 38343813.
Read At: PubMed
- Published on 1/16/2024
Savage TJ, Kronman MP, Huybrechts KF. Amoxicillin-Clavulanate vs Amoxicillin for Pediatric Acute Sinusitis-Reply. JAMA. 2024 Jan 16; 331(3):258-259. PMID: 38227036.
Read At: PubMed
- Published on 1/4/2024
Shupler M, Huybrechts K, Leung M, Wei Y, Schwartz J, Li L, Koutrakis P, Hernández-Díaz S, Papatheodorou S. Short-Term Increases in NO2 and O3 Concentrations during Pregnancy and Stillbirth Risk in the U.S.: A Time-Stratified Case-Crossover Study. Environ Sci Technol. 2024 Jan 16; 58(2):1097-1108. PMID: 38175714.
Read At: PubMed
- Published on 1/1/2024
Huybrechts KF, Olfson M. Evaluating the Liability of Antidepressants to Induce Mania in Children and Adolescents With Depression. JAMA Psychiatry. 2024 Jan 01; 81(1):13-14. PMID: 37755866.
Read At: PubMed
- Published on 12/26/2023
Cohen JM, Alvestad S, Suarez EA, Schaffer A, Selmer RM, Havard A, Bateman BT, Cesta CE, Zoega H, Odsbu I, Huybrechts KF, Kjerpeseth LJ, Straub L, Leinonen MK, Bjørk MH, Nørgaard M, Gissler M, Ulrichsen SP, Hernandez-Diaz S, Tomson T, Furu K. Comparative Risk of Major Congenital Malformations With Antiseizure Medication Combinations vs Valproate Monotherapy in Pregnancy. Neurology. 2024 Jan 23; 102(2):e207996. PMID: 38165339.
Read At: PubMed
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