Josée Dupuis
Profiles

Josee Dupuis, PhD

Adjunct Professor, Biostatistics - Boston University School of Public Health

617-358-2517
dupuis@bu.edu
Crosstown Center - 324
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Biography

Josée Dupuis, Ph.D, is an adjunct Professor of Biostatistics at Boston University School of Public Health (BUSPH). She was previously Chair of Biostatistics at BUSPH. She has held a faculty position at Northwestern University and a senior statistical geneticist position at Genome Therapeutics Corporation, a small biotech company. She has extensive experience in the development and application of methods for genome-wide association studies, gene by environment interaction investigation, genetic meta-analysis and rare variant analysis, with special emphasis on the development of novel statistical approaches to analyze genetic data collected on large families. She is involved in the Framingham Heart Study, collaborating on projects to identify genes influencing diabetes related traits and pulmonary function traits.

Other Positions

  • Investigator - Framingham Heart Study
  • Member, Bioinformatics Graduate Program - Boston University
  • Member, Genome Science Institute - Boston University

Education

  • Stanford University, PhD Field of Study: Statistics
  • Stanford University, MS Field of Study: Statistics
  • Concordia University, BS Field of Study: Statistics

Websites

Publications

  • Published on 1/14/2026

    Li J, Hu J, Yun H, Mei Z, Wang X, Luo K, Guasch-Ferré M, Han X, Truong B, Merino J, Jia C, Ruiz-Canela M, Rebholz CM, Moon EH, Alkis T, Liu G, Yao J, Zhang X, Porneala BC, Salas-Salvadó J, Wang TJ, Dupuis J, Selvin E, Guo X, Bhupathiraju SN, Brody JA, Liu Y, Wood AC, North KE, Jung SY, Liu CT, Sotoodehnia N, Liu S, Tinker LF, Eliassen AH, Manson JE, Florez JC, Gerszten RE, Clish CB, Liang L, Lemaitre RN, Tucker KL, Rich SS, Rotter JI, Martínez-González MA, Rexrode KM, Meigs JB, Boerwinkle E, Kaplan RC, Hu FB, Yu B, Qi Q. Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes. Nat Med. 2026 Jan 14. PMID: 41535386.

     Read At: PubMed
  • Published on 12/9/2025

    Wang N, Zhang Y, Schroeder P, Huerta-Chagoya A, Mandla R, Meigs JB, Manning AK, Liu CT, Dupuis J, Mercader JM. Evaluation of Sex-Stratified Polygenic Risk Scores for Type 2 Diabetes Mellitus and Glycemic Traits in the Framingham Heart Study. Diabetes Metab J. 2025 Dec 09. PMID: 41360390.

     Read At: PubMed
  • Published on 11/28/2025

    Sevilla-González M, Wang N, Hanson PA, Bebo A, Hitchcock D, Hsu S, Westerman KE, Cromer SJ, Barry VG, Borns-Weil Y, Zhang Y, Ben-Yossef O, Patel CJ, Franceschini N, Taylor KD, Ávila-Pacheco J, Clish CB, Gertzen RE, Raffield LM, Kooperberg C, Rich SS, Dupuis J, Rotter JI, Liu CT, Meigs JB, Manning AK. Dissecting Genetic and Environmental Determinants of Plasma Molecular Signatures and Their Link to Type 2 Diabetes Risk. medRxiv. 2025 Nov 28. PMID: 41358287.

     Read At: PubMed
  • Published on 11/17/2025

    Goldman-Pham R, Alter MP, Bao R, Collins SÉ, Debban CL, Allinson JP, Ambler A, Bertoni AG, Caspi A, Lovinsky-Desir S, Ekstrom MP, Engert JC, Jacobs DR, Malinsky D, Manichaikul A, Michos ED, Moffitt TE, Oelsner EC, Ramrakha S, Rich SS, Sack C, Stanojevic S, Subbarao P, Sugden K, Theodore R, Watson KE, Williams B, Yang B, Dupuis J, Shaheen SO, Barr RG, Hancox RJ, Smith BM. Quantifying the impact of early life growth adversity on later life health. Commun Med (Lond). 2025 Nov 17; 5(1):534. PMID: 41258496.

     Read At: PubMed
  • Published on 9/24/2025

    Sarnowski C, Zhang Y, Ammous F, Shade LMP, DiCorpo D, Jian X, Arnett DK, Austin TR, Beiser A, Bis JC, Blangero J, Boerwinkle E, Bressler J, Curran JE, DeCarli CS, Doddapaneni H, Dupuis J, Fardo DW, Florez JC, Gabriel S, Gibbs RA, Glahn DC, Gupta N, González HM, González KA, Hatzikotoulas K, Hayden KM, Heckbert SR, Hidalgo B, Huerta-Chagoya A, Hughes TM, Kardia SLR, Kooperberg CL, Launer LJ, Longstreth WT, Mandla R, Mathias RA, Morris AP, Mosley TH, Nasrallah IM, Nyquist P, Psaty BM, Qi Q, Raffield LM, Rayner NW, Reiner AP, Satizabal CL, Selvin E, Sevilla-Gonzalez MDR, Smith AV, Smith JA, Smith K, Snively BM, Southam L, Sofer T, Suzuki K, Taylor HJ, Udler MS, Viaud-Martinez KA, Wassertheil-Smoller S, Wood AC, Yanek LR, Yin X, Manning AK, Rotter JI, Rich SS, Meigs JB, Fornage M, Seshadri S, Morrison AC. Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program. Commun Biol. 2025 Sep 24; 8(1):1352. PMID: 40993182.

     Read At: PubMed
  • Published on 8/6/2025

    Ilori TO, Mamven M, Raji YR, Kwakyi E, Omotoso BA, Braimoh R, Solarin A, Umeizudike T, Zhao R, Kestenbaum B, Prince DK, Ripiye N, Ijeoma C, Slear J, Mumuni AA, Arogundade F, Salako BL, Gbadegesin R, Parekh RS, Dupuis J, Adu D, Ulasi I, Amira CO, Ojo A, Anderson CAM, Waikar SS. Association of Dietary Sodium and Potassium With Blood Pressure and Proteinuria in Africans With Kidney Disease. Kidney Int Rep. 2025 Oct; 10(10):3416-3430. PMID: 41141514.

     Read At: PubMed
  • Published on 4/29/2025

    Veerapaneni D, Arunachalam Sakthiyendran N, Du Y, Mallinger LA, Reinert A, Yeon Kim S, Nguyen C, Daneshmand A, Abdalkader M, Mohammed S, Dupuis J, Sheth KN, Gilmore EJ, Greer D, Ong CJ. Early Pupil Abnormality Frequency Predicts Poor Outcomes and Enhances International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) Model Prognostication in Traumatic Brain Injury. Crit Care Explor. 2025 May 01; 7(5):e1257. PMID: 40299976.

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  • Published on 4/8/2025

    Desai M, Messinger S, Ambrosius WT, Carlson NE, Dupuis J, Ghosh D, Hayat MJ, Landsittel D, Mayo MS, Oster RA, Roberson PK, Turk P. The Science of Statistical Practice. Acad Med. 2025 Sep 01; 100(9):1013-1017. PMID: 40198883.

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  • Published on 4/5/2025

    Song JJ, Stafford RA, Pohlmann JE, Kim ISY, Cheekati M, Dennison S, Brush B, Chatzidakis S, Huang Q, Smirnakis SM, Gilmore EJ, Mohammed S, Abdalkader M, Benjamin EJ, Dupuis J, Greer DM, Ong CJ. Later midline shift is associated with better post-hospitalization discharge status after large middle cerebral artery stroke. Sci Rep. 2025 Apr 05; 15(1):11738. PMID: 40188256.

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  • Published on 3/15/2025

    Sevilla-González M, Smith K, Wang N, Jensen AE, Litkowski EM, Kim H, DiCorpo DA, Hsu S, Cui J, Liu CT, Yu C, McNeil JJ, Lacaze P, Westerman KE, Chang KM, Tsao PS, Phillips LS, Goodarzi MO, Sladek R, Rotter JI, Dupuis J, Florez JC, Merino J, Meigs JB, Zhou JJ, Raghavan S, Udler MS, Manning AK. Heterogeneous effects of genetic variants and traits associated with fasting insulin on cardiometabolic outcomes. Nat Commun. 2025 Mar 15; 16(1):2569. PMID: 40089507.

     Read At: PubMed

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