Jaclyn Lee Fong Bosco, PhD
Adjunct Assistant Professor, Epidemiology - Boston University School of Public Health
Biography
Jaclyn Bosco, Sr Director, is the Global Scientific Head of Epidemiology and Biostatistics. She works with customers to develop strategies for using non-interventional study methods for real-world evidence generation to support the safety and effectiveness of drugs, biologics and biosimilars, and devices. She is experienced in helping customers refine their research questions based on various stakeholder needs, identifying the best approach for capturing data on a global scale as well applying local approaches to address market-specific needs, and designing and executing both primary and secondary data studies including medical chart review studies, patient registries, pregnancy registries, and comparative effectiveness and safety research studies. She has over 15 years of practical experience leading noninterventional research studies, and has conducted studies across the globe including North America, Europe, and Asia-Pacific regions. Dr. Bosco is responsible for scientific oversight, primarily in the areas of the design, analysis, and interpretation of non-interventional studies of comparative safety and effectiveness of medical treatments. She leads a global team of Epidemiologists and Outcomes Researchers and possesses considerable expertise in the application of epidemiologic methods to studies including propensity scoring, instrumental variable methods, bias analysis, and other methods for addressing bias in non-interventional studies. She is an epidemiology methods advisor on Scientific Advisory Boards, publishes articles in various leading peer-reviewed journals, presents at international and national meetings, reviews manuscripts and abstracts for high-impact journals and national conferences, co-authors book chapters, and teaches lectures in epidemiologic methods and biologics/biosimilars. Dr. Bosco is an Adjunct Assistant Professor of Epidemiology at Boston University School of Public Health, where she received her PhD in Epidemiology and MPH in Epidemiology and Biostatistics. She also completed her research fellowship with Dana Farber Cancer Institute/Harvard Medical School. She is currently a member of the International Society for Pharmacoepidemiology (ISPE) Education Committee (chair-elect) and Biologics & Biosimilars-SIG, International Society for Pharmacoeconomics and Outcomes Research (ISPOR), the Society for Epidemiologic Research (SER), and American Association of Cancer Research (AACR) Molecular Epidemiology Working Group and Behavioural Sciences in Cancer Research Working Group
Education
- Boston University School of Public Health, PhD Field of Study: Epidemiology
- Boston University School of Public Health, PhD Field of Study: Epidemiology
- Boston University School of Public Health, MPH Field of Study: Epidemiology
- University of California, Irvine, BS Field of Study: Biology
Websites
Publications
- Published on 5/1/2024
Gray C, Ralphs E, Fox MP, Lash TL, Liu G, Kou TD, Rivera DR, Bosco J, Braun KVN, Grimson F, Layton D. Use of quantitative bias analysis to evaluate single-arm trials with real-world data external controls. Pharmacoepidemiol Drug Saf. 2024 May; 33(5):e5796. PMID: 38680093.
Read At: PubMed
- Published on 1/1/2021
Bosco JLF. In Search of the Truth as an Epidemiologist in 2020. Epidemiology. 2021 01; 32(1):132-133. PMID: 33122566.
Read At: PubMed
- Published on 7/24/2015
Berry DL, Halpenny B, Bosco JLF, Bruyere J, Sanda MG. Usability evaluation and adaptation of the e-health Personal Patient Profile-Prostate decision aid for Spanish-speaking Latino men. BMC Med Inform Decis Mak. 2015 Jul 24; 15:56. PMID: 26204920.
Read At: PubMed
- Published on 3/1/2014
Lash TL, Thwin SS, Yood MU, Geiger AM, Bosco J, Quinn VP, Field TS, Pawloski PA, Silliman RA. Comprehensive evaluation of the incidence of late effects in 5-year survivors of breast cancer. Breast Cancer Res Treat. 2014 Apr; 144(3):643-63. PMID: 24584822.
Read At: PubMed
- Published on 10/11/2013
Buist DS, Bosco JL, Silliman RA, Gold HT, Field T, Yood MU, Quinn VP, Prout M, Lash TL. Long-term surveillance mammography and mortality in older women with a history of early stage invasive breast cancer. Breast Cancer Res Treat. 2013 Nov; 142(1):153-63. PMID: 24113745.
Read At: PubMed
- Published on 5/6/2013
Pawloski PA, Geiger AM, Haque R, Kamineni A, Fouayzi H, Ogarek J, Petersen HV, Bosco JL, Thwin SS, Silliman RA, Field TS. Fracture risk in older, long-term survivors of early-stage breast cancer. J Am Geriatr Soc. 2013 Jun; 61(6):888-95. PMID: 23647433.
Read At: PubMed
- Published on 3/28/2013
Hong F, Bosco JL, Bush N, Berry DL. Patient self-appraisal of change and minimal clinically important difference on the European organization for the research and treatment of cancer quality of life questionnaire core 30 before and during cancer therapy. BMC Cancer. 2013 Mar 28; 13:165. PMID: 23537330.
Read At: PubMed
- Published on 12/26/2012
Clough-Gorr KM, Thwin SS, Bosco JL, Silliman RA, Buist DS, Pawloski PA, Quinn VP, Prout MN. Incident malignancies among older long-term breast cancer survivors and an age-matched and site-matched nonbreast cancer comparison group over 10 years of follow-up. Cancer. 2013 Apr 15; 119(8):1478-85. PMID: 23280284.
Read At: PubMed
- Published on 11/1/2012
Gao H, Buist DS, Lash TL, Bosco JL, Swihart B. Lasagna plots made in different (statistical) ovens. Epidemiology. 2012 Nov; 23(6):934. PMID: 23038124.
Read At: PubMed
- Published on 9/28/2012
Bosco JL, Halpenny B, Berry DL. Personal preferences and discordant prostate cancer treatment choice in an intervention trial of men newly diagnosed with localized prostate cancer. Health Qual Life Outcomes. 2012 Sep 28; 10:123. PMID: 23021156.
Read At: PubMed
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