Yorghos Tripodis, PhD
Professor, Biostatistics - Boston University School of Public Health
Biography
Yorghos Tripodis is a Professor of Biostatistics. He has spent much of his career as an applied statistician collaborating with researchers in medicine and public health to address scientific questions with appropriate statistical methods. He has particular expertise in the analysis of longitudinal data. He serves as the Director for the Statistics and Data Management for the Framingham Heart Study and for the Boston University Alzheimer’s Disease and CTE Center (BU ADCTEC). Additionally, he directs the statistical analyses in multiple studies with researchers in medicine and public health to address issues of health disparities, especially among children. He is also serves as Statistical Editor in JAMA Internal Medicine.
Education
- London School of Economics and Political Science, PhD Field of Study: Statistics
- London School of Economics and Political Science, MSc Field of Study: Statistics
- University of Cambridge, MPhil Field of Study: Economics
- University of Athens, BSc Field of Study: Economics
Websites
Classes Taught
- SPHBS800
- SPHBS857
- SPHBS901
- SPHBS910
- SPHBS980
Publications
- Published on 12/1/2025
Gross CP, Richman IB, Stall NM, Kneifati-Hayek JZ, Allore HG, Rittenberg E, Katz MH, Grady D, Durant RW, Anderson TS, Tripodis Y, Wang TY, Corbie G, Mody L, Perlis RH, Ganguli I, Inouye SK. Artificial Intelligence and Clinical Care: JAMA Internal Medicine Call for Papers. JAMA Intern Med. 2025 Dec 01; 185(12):1418-1420. PMID: 41082189.
Read At: PubMed
- Published on 11/20/2025
Hartman S, Aytan N, Nicks R, Hawkins S, Cherry J, Alvarez VE, Meng G, Tripodis Y, Martin B, Palmisano J, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Crary JF, Alosco M, Xia W, McKee AC, Mez J, Stein TD. Genetic variation in TMEM106B alters microglial activation and cytokine responses in chronic traumatic encephalopathy. Acta Neuropathol. 2025 Nov 20; 150(1):54. PMID: 41264095.
Read At: PubMed
- Published on 11/10/2025
Wiegand TLT, Pankatz L, Arciniega H, Jung LB, Tuz-Zahra F, Bouix S, Lubeck H, Rojczyk P, Schuhmacher LS, Buring J, Katz DI, Tripodis Y, Pasternak O, Cetin-Karayumak S, Rathi Y, Adler CH, McKee AC, Balcer LJ, Bernick C, Coleman MJ, Colasurdo EA, Lin AP, Peskind ER, Ashton NJ, Blennow K, Zetterberg H, Alosco ML, Cummings JL, Reiman EM, Stern RA, Shenton ME, Koerte IK. Diffusion Alterations at the Gray Matter/White Matter Boundary in Traumatic Encephalopathy Syndrome. J Neurotrauma. 2025 Nov 10. PMID: 41218808.
Read At: PubMed
- Published on 11/7/2025
John O, Wickham A, Jung LB, Mirmajlesi AS, Stearns J, Breedlove K, Kim N, Daneshvar DH, Billah T, Pasternak O, Chamaria A, Coleman MJ, Tripodis Y, Adler CH, Bernick C, Balcer LJ, Rushmore RJ, Alosco ML, Koerte IK, Lin AP, Cummings JL, Reiman EM, Stern RA, Shenton ME, Arciniega H, Bouix S. Shape analysis of the amygdala, hippocampus and thalamus in former American football players. Brain Commun. 2025; 7(6):fcaf440. PMID: 41277896.
Read At: PubMed
- Published on 11/1/2025
Scott MR, Sverdlov O, Davis-Plourde K, Tripodis Y. Assessment of Wiener Process Degradation Models With Application to Amyotrophic Lateral Sclerosis Decline. Stat Med. 2025 Nov; 44(25-27):e70323. PMID: 41262008.
Read At: PubMed
- Published on 10/29/2025
Pulukuri SV, Spurlock EE, Tuz-Zahra F, Tripodis Y, Sampani K, Nicks R, Meng G, Alvarez VE, McKee AC, Xia W, Mordes DA, Subramanian ML, Stein TD. Vitreous STMN2 levels reflect TDP-43-associated neurodegeneration in postmortem eyes and brains. J Alzheimers Dis Rep. 2025; 9:25424823251392553. PMID: 41180957.
Read At: PubMed
- Published on 10/17/2025
Rubenstein E, Tewolde S, Michals A, Fortea J, Jimenez MP, Skotko BG, Tripodis Y, Weuve J, Rosellini AJ. Novel predictors of Alzheimer's disease in Down syndrome identified using machine learning. J Alzheimers Dis. 2025 Dec; 108(3):1166-1176. PMID: 41105592.
Read At: PubMed
- Published on 9/22/2025
Subramanian ML, Sampani K, Ness S, Tuz-Zahra F, Alluri S, Chen X, Siegel NH, Aytan N, Xia W, Tripodis Y, Alosco ML, Stein TD. Biomarkers for Alzheimer's disease are upregulated in patients with diabetic retinopathy. J Alzheimers Dis. 2025 Nov; 108(2):586-596. PMID: 40982223.
Read At: PubMed
- Published on 9/11/2025
Jung LB, Mirmajlesi AS, Stearns J, Breedlove K, John O, Kim N, Wickham A, Su Y, Protas H, Baucom ZH, Tuz-Zahra F, Tripodis Y, Daneshvar DH, Wiegand TLT, Billah T, Pasternak O, Heller C, Im BS, Datta S, Coleman MJ, Adler CH, Bernick C, Balcer LJ, Alosco ML, Lin AP, Cummings JL, Reiman EM, Stern RA, Shenton ME, Bouix S, Koerte IK, Arciniega H. Sulcal morphology in former American football players. Brain Commun. 2025; 7(5):fcaf345. PMID: 41048544.
Read At: PubMed
- Published on 9/1/2025
Alosco ML, Morrison M, Au R, Steinberg EG, Mwicigi J, Ly M, Altaras C, Lenio S, Abdennadher M, O'Connor MK, Tripodis Y, Palmisano J, Dixon D, Martin B, Schneider G, Groh JR, Ellison A, Sheppard D, Farris CW, Nowinski C, Cantu RC, Turk KW, Farrer L, Jun G, Goldstein LE, Qiu WQ, Stein TD, Budson AE, McKee AC, Mez J. Boston University Alzheimer's Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer's disease and related dementias. Alzheimers Dement. 2025 Sep; 21(9):e70654. PMID: 40923312.
Read At: PubMed
View 238 more publications:View Full Profile at BUMC
News & In the Media
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Published on September 13, 2024
Multiple Concussions Like Dolphins QB Tua Tagovailoa’s Increase Chances of Long-Term Health Issues
- Published on February 23, 2024
- Published on January 27, 2023
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Published on May 6, 2022
Selection Bias May Lead to Underestimation of CTE Risk in Former Football Players
- Published on March 17, 2021
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Published on September 17, 2019
Rob Gronkowski, Who Said He Had 20 Concussions, Claims He ‘Fixed’ His CTE
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Published on September 4, 2019
College Football Season Is Here. Will Universities Continue to Ignore the Risk of Brain Damage?
- Published on August 16, 2019
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Published on August 12, 2019
Triple Threat: Tau, Atrophy, and Arteriolosclerosis Push CTE Toward Dementia
- Published on July 29, 2019
- Published on July 22, 2019
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Published on July 22, 2019
Workplace Injuries Contribute to Rise in Suicide, Overdose Deaths
- Published on June 27, 2019
- Published on June 3, 2019
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Published on May 6, 2019
Massachusetts Latest State to Push Ban on Tackle Football for Kids
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Published on April 30, 2019
Four BU Professors Receive University’s Highest Faculty Honor
- Published on April 19, 2019
- Published on April 19, 2019
- Published on April 18, 2019
- Published on April 16, 2019
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Published on April 16, 2019
Researchers a Step Nearer to Detecting CTE in Living Individuals
- Published on April 12, 2019
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Published on April 12, 2019
Brain Scans Find CTE-Linked Protein in Living Former NFL Players
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Published on April 12, 2019
CTE Researchers Discover Possible Step Toward Diagnostic Test for Living Patients
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Published on April 12, 2019
A Study of NFL Players’ Brains Might Help Diagnose CTE in the Living
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Published on April 12, 2019
Brain Scans on Former NFL Players Detect Abnormal Proteins Found in CTE
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Published on April 12, 2019
Finding CTE in Living People? BU Just Got Closer to Doing It
- Published on April 12, 2019
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Published on April 12, 2019
A Study of NFL Players’ Brains Might Help Diagnose CTE in the Living
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Published on April 12, 2019
Abnormal Tau Protein Detected in CTE-Affected Living NFL Players’ Brains
- Published on April 12, 2019
- Published on April 12, 2019
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Published on April 12, 2019
Experimental Brain Scans May Reveal Concussion Damage in Living Athletes
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Published on April 12, 2019
Experimental Pet Scan Detects Abnormal Tau Protein in Brains of Former NFL Players
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Published on April 11, 2019
Abnormal Levels of a Protein Linked to C.T.E. Found in N.F.L Players’ Brains, Study Shows
- Published on April 11, 2019
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Published on April 11, 2019
Experimental PET Scan Detects Signs of CTE in Living Former NFL Players
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Published on April 4, 2019
Youth Tackle Football Will Be Considered Unthinkable 50 Years from Now
- Published on March 18, 2019
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Published on March 15, 2019
Central American Kidney Disease Epidemic Linked to Occupational Heat Exposure
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Published on March 14, 2019
Central American Kidney Disease Epidemic Linked to Occupational Heat Exposure
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Published on March 13, 2019
Bill to Ban Tackling in Youth Football Gains Ground on Beacon Hill
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Published on March 6, 2019
Massachusetts Bill Would Ban Tackle Football Until after Seventh Grade
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Published on March 1, 2019
Massachusetts Bill Would Ban Tackle Football Until after Seventh Grade
- Published on February 27, 2019
- Published on February 25, 2019
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Published on February 4, 2019
I’m Done Watching Football: The Toll on Players Is Too Great to Ignore
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Published on January 16, 2019
California Bill Would Limit Tackling During Youth Practices. Why It Has Leagues’ Support
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Published on November 28, 2018
Study: Just One Season of High School Football Can Change Teens’ Brains
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Published on November 20, 2018
Youth Football Programs Beginning to Put Safety First, Turning to Flag Football
- Published on November 2, 2018
- Published on August 7, 2018
- Published on August 3, 2018
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Published on June 4, 2018
As First CTE Trial Begins, Former Players Finally Get a Voice
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Published on May 9, 2018
When Does Youth Football Go from National Pastime to Public-Health Problem?
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Published on May 9, 2018
New Study Raises Questions Over When Kids Should Start Tackle Football
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Published on May 9, 2018
The Tragic Diagnosis They Already Knew: Their Brother Died with C.T.E.
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Published on May 9, 2018
Starting Tackle Football Early Sets Kids Up for Brain Problems
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Published on May 9, 2018
Naperville Park District Latest to Add Flag Football as Parents’ Fear of Concussions Grows
- Published on May 9, 2018
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Published on May 9, 2018
Out of the Dark: Late NHL Player with Chippewa Falls Ties Posthumously Diagnosed with CTE
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Published on April 30, 2018
Youth Tackle Football Linked to Earlier Onset of Cognitive and Emotional Symptoms
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Published on April 5, 2018
Evaluation and Treatment of Depression May Help Patients with Mild Cognitive Impairment
- Published on January 19, 2018
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Published on January 19, 2018
Repeated Head Hits, Not Just Concussions, May Lead to a Type of Chronic Brain Damage
- Published on January 18, 2018
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Published on September 26, 2017
Possible Biomarker for Diagnosing CTE During Life Identified
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Published on September 20, 2017
Link Found Between Youth Football and Later-Life Impairments
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Published on August 22, 2017
Evidence of CTE Found in Brains of Deceased Football Players
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Published on July 17, 2017
No Link Found Between Traumatic Brain Injury and Cognitive Decline
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Published on July 3, 2017
Continuing Search for Causes of Kidney Disease in Central America
- Published on July 25, 2016
- Published on April 4, 2016
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Published on February 2, 2015
Brain Study Shows Ex-NFL Players Negatively Affected by Youth Football