Tuhina Neogi
Profiles

Tuhina Neogi, MD, PhD

Professor, Epidemiology - Boston University School of Public Health

Biography

I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 300 peer-reviewed publications to date. I am a past chair of the FDA Arthritis Advisory Committee, serve(d) on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year), and the 2022 OARSI Clinical Research Award (in recognition of important contributions to OA research). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I also developed and led the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.

Expertise includes:
- Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
- Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
- Classification criteria and outcome measures in rheumatic diseases.
- Novel methodology to address challenging epidemiologic issues

Other Positions

  • Professor, Medicine - Boston University Chobanian & Avedisian School of Medicine
  • Chief, Medicine - Boston Medical Center
  • Investigator - Framingham Heart Study
  • Member, Arthritis & Autoimmune Diseases Research Center - Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research - Boston University
  • Section Chief of Rheumatology, Medicine - Boston University Chobanian & Avedisian School of Medicine

Education

  • University of Toronto, MD Field of Study: Medicine
  • Boston University School of Public Health, PhD Field of Study: Epidemiology
  • McMaster University, BS Field of Study: Biochemistry

Publications

  • Published on 5/5/2025

    Raut R, Chakraborty A, Neogi T, Albro M, Snyder B, Schaer T, Zhang C, Grinstaff M, Bais M. Constructing a cross-tissue human knee single-cell atlas identified osteoarthritis reduces regenerative tissue stem cells while increasing inflammatory pain macrophages. Res Sq. 2025 May 05. PMID: 40386432.

    Read At: PubMed
  • Published on 4/28/2025

    Neogi T, Dubreuil M, Peloquin C, Marinko L, Camarinos J, Felson DT, Kumar D. Reply. Arthritis Rheumatol. 2025 Apr 28. PMID: 40289862.

    Read At: PubMed
  • Published on 3/18/2025

    Lee S, Neogi T, Senderling BM, Jafarzadeh SR, Gheller M, Tuttle PG, Demanuele C, Viktrup L, Wacnik P, Kumar D. Association of Pain During Exercise With Exercise-Induced Hypoalgesia in People With Knee Osteoarthritis. Arthritis Care Res (Hoboken). 2025 Mar 18. PMID: 40099368.

    Read At: PubMed
  • Published on 3/16/2025

    Neogi T, Dubreuil M, Peloquin C, Marinko L, Camarinos J, Felson DT, Kumar D. Association of Physical Therapy Care With Use of Intra-Articular Injections in People With Knee Osteoarthritis: A Real-World Cohort Study. Arthritis Rheumatol. 2025 Mar 16. PMID: 40091450.

    Read At: PubMed
  • Published on 3/13/2025

    Liew JW, Johnston JD, Bacon K, Wang N, Lynch J, Lewis C, Torner J, Neogi T. Relationship between knee pain and depth-specific measures of proximal tibial subchondral bone density. Osteoarthritis Cartilage. 2025 May; 33(5):625-632. PMID: 40089263.

    Read At: PubMed
  • Published on 3/6/2025

    Neelapala YR, Neogi T, Hanna S, Frey-Law LA, Macedo LG, Kobsar D, Lewis CE, Nevitt M, Carlesso L. Latent transition analysis of pain phenotypes in people at risk of knee osteoarthritis: The MOST cohort study. Osteoarthritis Cartilage. 2025 May; 33(5):616-624. PMID: 40057018.

    Read At: PubMed
  • Published on 3/1/2025

    Solomon DH, Paudel M, Chitineni S, Fernandes A, Pham T, Billa S, Yokose C, Tan K, Dedier JJ, Dubreuil MD, Fitzgerald JD, Hodder SL, Neogi T, Pillinger MH, Riggs KR, Saag KG, Shekelle PG, Tseng Z, Toprover M, Wei DS, Barry MJ, Choi HK. The Design of a Randomized Controlled Active Comparator Strategy Trial for Gout: Treat to Target Serum Urate Versus Treat to Avoid Symptoms. ACR Open Rheumatol. 2025 Mar; 7(3):e70012. PMID: 40126890.

    Read At: PubMed
  • Published on 2/13/2025

    Tang S, Zhang C, Oo WM, Fu K, Risberg MA, Bierma-Zeinstra SM, Neogi T, Atukorala I, Malfait AM, Ding C, Hunter DJ. Osteoarthritis. Nat Rev Dis Primers. 2025 Feb 13; 11(1):10. PMID: 39948092.

    Read At: PubMed
  • Published on 2/5/2025

    Bordvik DH, Steen Pettersen P, Gløersen M, Mulrooney E, Neogi T, Kjeken I, Haugen IK. The associations between sleep problems and pain outcomes in people with hand osteoarthritis - Data from the Nor-hand study. Osteoarthr Cartil Open. 2025 Mar; 7(1):100579. PMID: 40034602.

    Read At: PubMed
  • Published on 2/4/2025

    Kim E, Neogi T, Lee S, Kumar D. Relation of pain sensitization to knee loading during walking in people with knee osteoarthritis. Osteoarthritis Cartilage. 2025 Apr; 33(4):509-516. PMID: 39914522.

    Read At: PubMed

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