
Tuhina Neogi, MD, PhD
Professor, Epidemiology - Boston University School of Public Health
Biography
I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 300 peer-reviewed publications to date. I am a past chair of the FDA Arthritis Advisory Committee, serve(d) on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year), and the 2022 OARSI Clinical Research Award (in recognition of important contributions to OA research). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I also developed and led the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.
Expertise includes:
- Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
- Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
- Classification criteria and outcome measures in rheumatic diseases.
- Novel methodology to address challenging epidemiologic issues
Other Positions
- Professor, Medicine - Boston University Chobanian & Avedisian School of Medicine
- Chief, Medicine - Boston Medical Center
- Investigator - Framingham Heart Study
- Member, Arthritis & Autoimmune Diseases Research Center - Boston University
- Member, Evans Center for Interdisciplinary Biomedical Research - Boston University
- Section Chief of Rheumatology, Medicine - Boston University Chobanian & Avedisian School of Medicine
Education
- University of Toronto, MD Field of Study: Medicine
- Boston University School of Public Health, PhD Field of Study: Epidemiology
- McMaster University, BS Field of Study: Biochemistry
Publications
- Published on 9/22/2025
Degirmenci HB, Peloquin CE, Westerland M, Lodi S, Machado PM, Jafarzadeh SR, Neogi T, Gensler LS, Dubreuil M, Liew JW. Trends in Opioid Prescriptions in Individuals with Axial Spondyloarthritis in the US and UK in the Last Two Decades: Analysis of Electronic Health Records and Insurance Claims Data. Arthritis Care Res (Hoboken). 2025 Sep 22. PMID: 40977482.
Read At: PubMed
- Published on 9/5/2025
George N, Liew JW, Wang N, Tilley S, Guermazi A, Lynch J, Lewis C, Torner J, Neogi T. Does hsCRP provide insights into an inflammatory phenotype of knee osteoarthritis? Osteoarthritis Cartilage. 2025 Sep 05. PMID: 40915380.
Read At: PubMed
- Published on 8/29/2025
Dalbeth N, Stewart S, Gamble GD, Mihov B, Stamp LK, Haslett J, Taylor WJ, Merriman TR, Tabi-Amponsah AD, Horne A, Neogi T, Pascart T, Andrés M, Peral-Garrido ML, Norkuviene E, Mellado JV, Uhlig T, Sun M, Li C, Petrie KJ. Perceptions about asymptomatic hyperuricemia and views about urate-lowering therapy in people with asymptomatic hyperuricemia. Arthritis Care Res (Hoboken). 2025 Aug 29. PMID: 40884020.
Read At: PubMed
- Published on 8/12/2025
Aoyagi K, Wang N, LaValley M, Tilley S, Frey-Law L, Lewis CE, Nevitt M, Neogi T. Longitudinal Trajectories of Pain Sensitization Over Nine Years in People With or at Risk of Knee Osteoarthritis. Arthritis Care Res (Hoboken). 2025 Aug 12. PMID: 40790991.
Read At: PubMed
- Published on 8/7/2025
Barry A, England BR, Sayles H, Helget LN, Androsenko M, Wu H, Michaud K, Kramer B, Newcomb JA, Brophy MT, Davis-Karim A, Ferguson R, Pillinger MH, Neogi T, Palevsky PM, O'Dell JR, Mikuls TR. Improvements in Health-Related Quality of Life with Treat-to-Target Urate-Lowering Therapy in Gout: A Post-hoc Analysis of a Randomized Multicenter Trial. Arthritis Care Res (Hoboken). 2025 Aug 07. PMID: 40771143.
Read At: PubMed
- Published on 8/5/2025
Kohn S, Sayles H, Helget LN, England BR, Roul P, Newcomb JA, Kramer B, Davis-Karim A, Brophy MT, Ferguson R, Pillinger MH, Neogi T, Palevsky PM, Wu H, O'Dell JR, Mikuls TR. Real-world persistence of urate-lowering therapy following a treat-to-target intervention: A two-year follow-up analysis of the STOP gout trial. Semin Arthritis Rheum. 2025 Oct; 74:152800. PMID: 40782426.
Read At: PubMed
- Published on 8/4/2025
Helget LN, England BR, Roul P, Sayles H, Neogi T, O'Dell JR, Baker JF, Mikuls TR. Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration. Arthritis Care Res (Hoboken). 2025 Aug 04. PMID: 40757470.
Read At: PubMed
- Published on 8/4/2025
Wu Y, Liew JW, Boer JD, Westerland M, LaValley M, Voortman T, Bierma-Zeinstra S, Oei EHG, van Meurs JBJ, Neogi T, Boer CG. Chondrocalcinosis and incident knee osteoarthritis: findings from 2 large prospective cohorts with 20 years of follow-up. Ann Rheum Dis. 2025 Aug 04. PMID: 40764183.
Read At: PubMed
- Published on 8/2/2025
Raut RD, Chakraborty AK, Neogi T, Albro M, Snyder B, Schaer TP, Zhang C, Grinstaff MW, Bais MV. A multi-tissue human knee single-cell atlas identifies that osteoarthritis reduces regenerative tissue stem cells while increasing inflammatory pain macrophages. Commun Biol. 2025 Aug 02; 8(1):1146. PMID: 40753276.
Read At: PubMed
- Published on 8/1/2025
Jauffret C, Tedeschi SK, Abhishek A, Latourte A, Filippou G, Neogi T, Pascart T. Calcium pyrophosphate crystal deposition: 2025 update to recent epidemiological findings. Curr Opin Rheumatol. 2025 Nov 01; 37(6):437-444. PMID: 40747977.
Read At: PubMed
View 398 more publications:View Full Profile at BUMC
News & In the Media
- Published on March 7, 2024
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Published on March 1, 2024
Groundbreaking Study Uncovers How Calcium Crystals in Knees Accelerate Arthritis Progression
- Published on March 1, 2024
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Published on January 21, 2022
Colchicine as COVID-19 Treatment Suffers Difficult Year, but Some Hope Remains
- Published on February 26, 2021
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Published on September 16, 2020
How Top Experts Are Advancing Gout Care in the United States
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Published on September 9, 2020
Study: Why People With Knee Osteoarthritis Experience Different Kinds of Pain.
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Published on September 9, 2020
Scientists Discover Key Cause of Different Kinds of Pain Suffered by Osteoarthritis Patients
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Published on September 9, 2020
Tuhina Neogi, MD, PhD, National Leader in Gout Management, on New ACR Guidelines
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Published on September 8, 2020
Study: Why People With Knee Osteoarthritis Experience Different Kinds of Pain
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Published on September 8, 2020
Osteoarthritis Gives Us Unbearable Pain. Why Does It Happen?
- Published on August 10, 2020
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Published on August 10, 2020
Study Finds Bone Drug May Be Beneficial for Knee Osteoarthritis
- Published on July 31, 2020
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Published on July 23, 2020
Coronavirus Fears Keep Patients With Severe Chronic Pain From Seeking Care
- Published on May 13, 2020
- Published on April 8, 2020
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Published on April 7, 2020
Obesity Increases Likelihood of Long-Term Prescription Opioid Use, Researchers Find
- Published on April 2, 2020
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Published on December 19, 2019
Canagliflozin May Reduce Gout Flare Risk in People with Type 2 Diabetes
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Published on December 18, 2019
SGLT2 Inhibitor Canagliflozin Reduces Gout Flares in Type 2 Diabetes: CANVAS Program
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Published on December 17, 2019
Failure of Management: Treatment Gaps at the Root of Dismal Gout Care
- Published on December 16, 2019
- Published on December 16, 2019
- Published on December 14, 2019
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Published on December 13, 2019
Boston University Finds Concerns about Other Painkillers Contributed to Opioid Crisis
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Published on December 13, 2019
Health Risks of NSAIDs Led to ‘Significant Under-Treatment of Pain’
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Published on November 18, 2019
Gout Guidelines Call for Treat-To-Target Strategy Using Allopurinol
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Published on November 15, 2019
ACR: Draft OA Guidelines Stress Non-Drug Tx, Leave Opioid Door Open
- Published on November 13, 2019
- Published on November 12, 2019
- Published on May 2, 2019
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Published on April 19, 2019
Dietary Omega-3 Fatty Acids Linked to Lower Risk of Recurrent Gout Flare
- Published on March 28, 2019
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Published on November 5, 2018
Becoming More Sensitive to Pain Increases Risk of Knee Pain Not Going Away
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Published on November 2, 2018
Becoming More Sensitive to Pain Increases the Risk of Knee Pain Not Going Away
- Published on October 24, 2018
- Published on October 24, 2018
- Published on October 24, 2018
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Published on October 24, 2018
Un medicamento para la gota puede proteger contra la enfermedad renal crónica
- Published on October 9, 2018
- Published on October 9, 2018
- Published on October 9, 2018
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Published on October 9, 2018
Studien: Sind NSAID und Allopurinol weniger gefährlich als angenommen?
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Published on October 9, 2018
Un medicamento para la gota puede proteger contra la enfermedad renal crónica
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Published on October 9, 2018
Allopurinol for Gout an Unlikely Contributor to Kidney Disease Progression
- Published on October 9, 2018