Jayandra Himali
Profiles

Jayandra Jung Himali, PhD

Adjunct Associate Professor, Neurology - Boston University Chobanian & Avedisian School of Medicine

(617) 638-5139
Crosstown Center
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Biography

Jayandra Jung Himali, PhD, serves as an adjunct Associate Professor of Neurology and Biostatistics at Boston University Schools of Medicine and of Public Health, and a Center Faculty Member of the Framingham Heart Study (FHS). He has been engaged in collaborative public health research and teaching for over a decade. As a senior Biostatistician at the Neurology core of FHS, his research efforts are focused on the interrelated areas of: (1) the epidemiology of dementia and Alzheimer’s disease (AD) and relating traditional and novel biomarkers to the risk of dementia and AD; (2) the epidemiology of stroke and vascular cognitive impairment; (3) understanding vascular contributions to cognitive impairment and dementia including AD; and (4) investigating the role of modifiable lifestyle factors: sleep, diet and physical activity on the incidence of dementia, cognitive decline and MRI-defined brain aging. His research is also focused on outcome assessment in Epilepsy, Parkinson’s disease, and neuropathology. He has received the Nepal Bidhya Bhusan Class ‘A’ Medal from the government of Nepal for highest academic achievement in doctoral studies.

Other Positions

  • Investigator - Framingham Heart Study

Education

  • Boston University School of Public Health, PhD Field of Study: Biostatistics
  • Tribhuvan University, MSc Field of Study: Statistics
  • Tribhuvan University, BSc Field of Study: Statistics

Websites

Publications

  • Published on 1/23/2026

    Young VM, Zeynoun J, Ruiz Laza A, Salardini A, Frei CR, Gaspard C, Kautz T, Macedo E Cordeiro T, Pase MP, Gelfond J, Himali JJ, Teixeira AL, Seshadri S, Baril AA. Association between sleep duration and fluid biomarkers of Alzheimer's disease: A systematic review. Sleep Med Rev. 2026 Jan 23; 86:102242. PMID: 41610733.

     Read At: PubMed
  • Published on 1/20/2026

    Francis L, Beiser A, Lu S, Kujawa SG, Heard-Costa N, Kolo FB, Kamboh MI, Bernal R, Welling DB, Alcabes RL, Himali JJ, Seshadri S. Hearing loss in the young-old is associated with increased risk for Alzheimer's disease and vascular dementia. J Alzheimers Dis. 2026 Feb; 109(3):1142-1148. PMID: 41555782.

     Read At: PubMed
  • Published on 1/19/2026

    Romero JR, Pinheiro A, Demissie S, Aparicio HJ, Lioutas VA, Charidimou A, Beiser A, Ekenze O, Himali JJ, DeCarli C, Seshadri S, Mohammed S. Lifelong trajectories of modifiable vascular risk factors and relation to cerebral small vessel disease in the Framingham Heart Study. medRxiv. 2026 Jan 19. PMID: 41646706.

     Read At: PubMed
  • Published on 1/1/2026

    Li JM, Gauen AM, Zmora R, Stephen JJ, Petito LC, Scholtens D, Peterson EA, Kohli-Lynch C, Mansolf M, Sedaghat S, Giorgio K, Gross AL, Helmer C, Debette S, Soumaré A, Ikram MA, Wolters FJ, Seshadri S, Satizabal CL, Himali J, Levine DA, Briceño EM, Sorond FA, Launer LJ, Li D, Mbangdadji D, Zhao L, Lloyd-Jones DM, Lopez OL, Judd SE, Hughes TM, Gudnason V, Aiello AE, Fohner A, Singh-Manoux A, Allen NB. Midlife and late-life population attributable fractions of risk factors for dementia in the United States: The Dementia Risk Prediction Project. Alzheimers Dement. 2026 Jan; 22(1):e71065. PMID: 41559019.

     Read At: PubMed
  • Published on 12/18/2025

    Yiallourou S, Wiedner C, Yang Q, Baril AA, Misialek JR, Kline CE, Harrison S, Bernal R, Bisson A, Himali D, Chiu T, Cavuoto M, Ancoli-Israel S, Xiao Q, Vaou EO, Weihs A, Leng Y, Gottesman RF, Beiser A, Lopez O, Lutsey PL, Purcell SM, Redline S, Seshadri S, Stone KL, Yaffe K, Pase MP, Himali JJ. A data driven approach to assess relationships between sleep, cognition and dementia: Findings from the Sleep and Dementia Consortium. medRxiv. 2025 Dec 18. PMID: 41445661.

     Read At: PubMed
  • Published on 12/16/2025

    Palatsides EL, Himali D, Cribb L, Peloso GM, Ryan J, Yang Q, DeCarli CS, Beiser AS, Seshadri S, Cavuoto MG, Yiallourou S, Baril AA, Himali JJ, Pase MP. Association of an Aquaporin-4 Haplotype with Cognition, Brain Volume, and Dementia Risk in Community-Dwelling Individuals without Dementia. medRxiv. 2025 Dec 16. PMID: 41445666.

     Read At: PubMed
  • Published on 11/24/2025

    Karkar KM, Koneru S, Werry-McFarlin A, Karkar MC, Wiedner CD, Himali JJ, Papanastassiou A, Szabo CA. High-Gain Analysis of Postictal sEEG Suppression Identifies Otherwise Invisible Multifrequency Activity, Including Persisting Ictal Discharges. J Clin Neurophysiol. 2025 Nov 24. PMID: 41380013.

     Read At: PubMed
  • Published on 11/3/2025

    Kolo FB, Lu S, Beiser AS, Francis L, Melo van Lent D, Gireud-Goss M, Himali JJ, Ghosh S, Ting SJ, Banerjee A, Kowalczyk TL, Zucker JM, Heard-Costa N, Wood CG, Maillard P, Fletcher EM, DeCarli CS, Welling DB, Kujawa SG, Seshadri S. Hearing Loss, Brain Structure, Cognition, and Dementia Risk in the Framingham Heart Study. JAMA Netw Open. 2025 Nov 03; 8(11):e2539209. PMID: 41191359.

     Read At: PubMed
  • Published on 10/2/2025

    Wadop YN, Bernal R, Njamnshi WY, Satizabal CL, Beiser A, Ruiz A, Njamnshi AK, Vasan RS, Seshadri S, Himali JJ, Fongang B. Altered gut microbiota mediates the association between APOE genotype and amyloid-ß accumulation in middle-aged adults. J Neurol. 2025 Oct 02; 272(10):670. PMID: 41037094.

     Read At: PubMed
  • Published on 9/9/2025

    Yiallourou S, Baril AA, Wiedner C, Misialek JR, Kline CE, Harrison S, Cannon E, Yang Q, Bernal R, Bisson A, Himali D, Cavuoto M, Weihs A, Beiser A, Gottesman RF, Leng Y, Lopez O, Lutsey PL, Purcell SM, Redline S, Seshadri S, Stone KL, Yaffe K, Ancoli-Israel S, Xiao Q, Vaou EO, Himali JJ, Pase MP. Sleep architecture and dementia risk in adults: an analysis of 5 cohorts from the Sleep and Dementia Consortium. Sleep. 2025 Sep 09; 48(9). PMID: 40377976.

     Read At: PubMed

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