David Kaufman
Profiles

David W Kaufman, ScD

Professor, Epidemiology - Boston University School of Public Health

(617) 206-6146
dwk@bu.edu
Slone Epidemiology Center
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Biography

David W. Kaufman is Professor of Epidemiology at the Boston University School of Public Health and Director of the Slone Epidemiology Center. He obtained his M.S. and Sc.D. in Epidemiology from Harvard School of Public Health. In 1975 he joined the newly created Drug Epidemiology Unit (now the Slone Epidemiology Center ) as a Research Associate. His early career as an epidemiologist at the DEU was primarily spent in studies of drugs and other factors in relation to cancer, heart disease, and various other conditions. Together with Drs. Slone, Shapiro, and Lynn Rosenberg, he participated in the development of Case-Control Surveillance. In the 1980s, Dr. Kaufman was co-investigator of the International Agranulocytosis and Aplastic Anemia Study, a pioneering effort in the evaluation of these extremely rare but often drug-induced blood dyscrasias that was conducted in seven countries with several hundred cases enrolled. He has directed studies of aplastic anemia in Thailand and the United States. The Thai study is the largest epidemiological investigation of aplastic anemia that has been conducted, with over 500 cases and 2200 controls. Dr. Kaufman pursued his interest in rare drug induced diseases as principal investigator of an international study of Stevens-Johnson syndrome and toxic epidermal necrolysis conducted in four countries in Europe, and a study of anaphylaxis conducted in Spain, Hungary, India, and Sweden. Other major activities have included an international study of analgesics in relation to upper gastrointestinal bleeding and the National Analgesic Nephropathy Study, a multicenter study of end stage renal disease patients in three regions of the U.S. Dr. Kaufman worked closely with Allen Mitchell in the implementation of the Slone Survey, a U.S. population-based survey of medication use. He was principal investigator of a recently completed study that documented an inverse relationship between Oxalobacter formigenes, an oxalate metabolizing bacterium found in the colons of about 40% of the normal population, and calcium oxalate kidney stones. He also directed the Patient Registries at Slone: Myeloma and MDS, a recent nationwide effort that followed patients with the two diseases through the course of their illness. Currently Dr. Kaufman is co-principal investigator for a large scale behavioral surveillance program of acetaminophen users and is involved in other postmarketing surveillance activities. He was Assistant Director of the Slone Epidemiology Unit from 1986 to 1997, and was Associate Director from 1998 to 2016.

Other Positions

  • Director, Slone Epidemiology Center - Boston University Medical Campus

Education

  • Harvard University, ScD Field of Study: Epidemiology
  • Harvard University, MS Field of Study: Epidemiology
  • Bethel College, BA Field of Study: History

Websites

Publications

  • Published on 7/19/2022

    Teller P, Nguyen TT, Tseng J, Allen L, Matsen CB, Bellavance E, Kaufman D, Hieken T, Nagel S, Patten C, Pomerenke L, Tevis SE, Sarantou T. Innovation in Breast Surgery: Practical and Ethical Considerations. Ann Surg Oncol. 2022 Oct; 29(10):6144-6150. PMID: 35854028.

     Read At: PubMed
  • Published on 3/15/2022

    Wiestner A, Issaragrisil S, Kaufman DW, Ozawa K, Nakao S, Kajigaya S, Wang J, Wu Z, Binh VTT, Dhawan R, Nair V. Collaborations, colleagues, and friendships: The Hematology Branch and blood disease centers in Asia. Semin Hematol. 2022 Jan; 59(1):6-12. PMID: 35491061.

     Read At: PubMed
  • Published on 8/31/2021

    Sulaiman I, Chung M, Angel L, Tsay JJ, Wu BG, Yeung ST, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal SA, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Pérez-Pérez L, Shen G, Jour G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman DH, Weiden M, Heguy A, Evans L, Uyeki TM, Clemente JC, de Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst CV, Koide S, Stapleford KA, Khanna KM, Ghedin E, Segal LN. Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome. Nat Microbiol. 2021 Oct; 6(10):1245-1258. PMID: 34465900.

     Read At: PubMed
  • Published on 4/1/2020

    Ascierto PA, Fox BA, Urba WJ, Anderson AC, Atkins MB, Borden EC, Brahmer JR, Butterfield LH, Cesano A, Chen DC, de Gruijl TD, Dillman RO, Drake CG, Emens LA, Gajewski TF, Gulley JL, Stephen Hodi FJ, Hwu P, Kaufman D, Kaufman HL, Lotze MT, McNeel DG, Margolin KM, Marincola FM, Mastrangelo MJ, Maus MV, Parkinson DR, Romero PJ, Sondel PM, Spranger S, Sznol M, Weiner GJ, Wigginton JM, Weber JS. Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19. J Immunother Cancer. 2020 Apr; 8(1). PMID: 32300051.

     Read At: PubMed
  • Published on 3/18/2019

    Kaufman DW, Kelly JP, Battista DR, Malone MK, Weinstein RB, Shiffman S. Five-year trends in acetaminophen use exceeding the recommended daily maximum dose. Br J Clin Pharmacol. 2019 05; 85(5):1028-1034. PMID: 30740763.

     Read At: PubMed
  • Published on 10/12/2018

    Cristescu R, Mogg R, Ayers M, Albright A, Murphy E, Yearley J, Sher X, Liu XQ, Lu H, Nebozhyn M, Zhang C, Lunceford JK, Joe A, Cheng J, Webber AL, Ibrahim N, Plimack ER, Ott PA, Seiwert TY, Ribas A, McClanahan TK, Tomassini JE, Loboda A, Kaufman D. Pan-tumor genomic biomarkers for PD-1 checkpoint blockade-based immunotherapy. Science. 2018 Oct 12; 362(6411). PMID: 30309915.

     Read At: PubMed
  • Published on 7/21/2018

    Kelly JP, Battista DR, Shiffman S, Malone MK, Weinstein RB, Kaufman DW. Knowledge of dosing directions among current users of acetaminophen-containing medications. J Am Pharm Assoc (2003). 2018 Sep - Oct; 58(5):492-498. PMID: 30041852.

     Read At: PubMed
  • Published on 7/17/2018

    Shiffman S, Battista DR, Kelly JP, Malone MK, Weinstein RB, Kaufman DW. Exceeding the maximum daily dose of acetaminophen with use of different single-ingredient OTC formulations. J Am Pharm Assoc (2003). 2018 Sep - Oct; 58(5):499-504. PMID: 30030041.

     Read At: PubMed
  • Published on 3/25/2018

    Shiffman S, Battista DR, Kelly JP, Malone MK, Weinstein RB, Kaufman DW. Prevalence of exceeding maximum daily dose of paracetamol, and seasonal variations in cold-flu season. Br J Clin Pharmacol. 2018 06; 84(6):1250-1257. PMID: 29516533.

     Read At: PubMed
  • Published on 1/26/2018

    Kaufman DW, Kelly JP, Battista DR, Malone MK, Weinstein RB, Shiffman S. Exceeding the daily dosing limit of nonsteroidal anti-inflammatory drugs among ibuprofen users. Pharmacoepidemiol Drug Saf. 2018 03; 27(3):322-331. PMID: 29372579.

     Read At: PubMed

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