Brooke Nichols
Profiles

Brooke Nichols

Assistant Professor, Global Health - Boston University School of Public Health

Biography

Brooke Nichols, PhD, MSc, is an infectious disease mathematical modeller and health economist working on both transmission dynamics for pathogens such as SARS-CoV-2, HIV and tuberculosis as well as optimal resource allocation to minimize the impact of these pathogens on human health. She is currently the co-lead of the World Health Organization (WHO) and Foundation for Innovative New Diagnostics (FIND)’s Access to COVID-19 Tools Accelerator (ACT-A) SARS-CoV-2 diagnostics modelling consortium. The modelling consortium focuses on optimizing the use of rapid antigen testing for SARS-CoV-2 in low- and middle-income countries.

Dr. Nichols’ research team is a multi-continental group of quantitative scientists and modellers focused on bridging the gap between traditional clinical science, epidemiology, health economics, mathematical modelling and actionable implementation. Through the development of novel quantitative methods and repurposing of existing methods, they design cost-effective and implementable interventions and programmes aimed at the reduction of transmission, morbidity, and mortality of infectious diseases. Using these novel approaches, Dr. Nichols and team have successfully guided and advised on national and international policy related to HIV (pre-exposure prophylaxis, HIV self-testing, differentiated service delivery, viral load monitoring), tuberculosis (diagnostics, multi-drug resistant tuberculosis treatment regimens), and SARS-CoV-2 (diagnostic testing algorithms).

Education

  • Erasmus Universiteit Rotterdam, PhD Field of Study: Public Health
  • University of Massachusetts Amherst, MS Field of Study: Epidemiology
  • Mount Holyoke College, BA Field of Study: International Relations

Classes Taught

  • SPHPH867

Publications

  • Published on 5/1/2022

    Phillips AN, Bershteyn A, Revill P, Bansi-Matharu L, Kripke K, Boily MC, Martin-Hughes R, Johnson LF, Mukandavire Z, Jamieson L, Meyer-Rath G, Hallett TB, Ten Brink D, Kelly SL, Nichols BE, Bendavid E, Mudimu E, Taramusi I, Smith J, Dalal S, Baggaley R, Crowley S, Terris-Prestholt F, Godfrey-Faussett P, Mukui I, Jahn A, Case KK, Havlir D, Petersen M, Kamya M, Koss CA, Balzer LB, Apollo T, Chidarikire T, Mellors JW, Parikh UM, Godfrey C, Cambiano V. Cost-effectiveness of easy-access, risk-informed oral pre-exposure prophylaxis in HIV epidemics in sub-Saharan Africa: a modelling study. Lancet HIV. 2022 May; 9(5):e353-e362. PMID: 35489378.

    Read At: PubMed
  • Published on 4/22/2022

    Perspectives on the use of modelling and economic analysis to guide HIV programmes in sub-Saharan Africa. Lancet HIV. 2022 Apr 22. PMID: 35468318.

    Read At: PubMed
  • Published on 2/6/2022

    Felix Garza ZC, de Jong SPJ, Gibson J, Han AX, van Leeuwen S, de Vries RP, Boons G-J, van Hoesel M, de Haan K, van Groeningen L, van Wiligen HDG, Wynberg E, de Bree GJ, Master A, van der Hoek L, Prins M, Koostra NA, Eggink D, Nichols BE, de Jong MD, Russell CA. Impacts of the COVID-19 pandemic on future seasonal influenza epidemics. medRxiv. 2022.

    Read At: Custom
  • Published on 1/3/2022

    van der Straten K, Guerra D, van Gils M, Bontjer I, Caniels TG, van Willigen HD, Poniman M, Burger JA, Bouhuijs JH, Lavell A, Appelman B, Sikkens JJ, Bomers M, Han AX, Nichols BE, Prins M, Vennema H, Reusken C, Eggink D, de Jong M, de Bree GJ, Russell CA, Sanders RW. Mapping the antigenic diversification of SARS-CoV-2. medRxiv. 2022.

    Read At: Custom
  • Published on 12/19/2021

    Hendrickson C, Long LC, van Rensburg C, Claassen C, Njelesani M, Moyo C, Mulenga L, Obra H, Russell CA, Nichols BE. The early-stage comprehensive costs of routine PrEP implementation and scale-up in Zambia. medRxiv. 2021.

    Read At: Custom
  • Published on 12/8/2021

    Rosen S, Nichols B, Guthrie T, Benade M, Kuchukhidze S, Long L. Do differentiated service delivery models for HIV treatment in sub-Saharan Africa save money? Synthesis of evidence from field studies conducted in sub-Saharan Africa in 2017-2019. Gates Open Res. 2021; 5:177. PMID: 35310814.

    Read At: PubMed
  • Published on 12/8/2021

    Silal S, Pulliam J, Jamieson L, Nichols B, Moultrie H, Meyer-Rath G. The role of modelling in planning and budgeting for SA's COVID-19 response. South African Health Review. 2021.

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  • Published on 11/22/2021

    Thorp M, Balakasi K, Mphande M, Robson I, Khan S, Stillson C, Doi N, Nichols BE, Dovel K. Factors Associated with Men's Health Facility Attendance as Clients and Caregivers in Malawi: A Community-Representative Survey. SSRN. 2021.

    Read At: Custom
  • Published on 11/19/2021

    Benade M, Nichols BE, Fatti G, Kuchukhidze S, Takarinda K, Mabhena-Ngorima N, Grimwood A, Rosen S. Economic evaluation of a cluster randomized, non-inferiority trial of differentiated service delivery models of HIV treatment in Zimbabwe. medRxiv. 2021.

    Read At: Custom
  • Published on 11/16/2021

    Sy KTL, White LF, Nichols BE. Reproducible Science Is Vital for a Stronger Evidence Base During the COVID-19 Pandemic. Geogr Anal. 2021 Nov 16. PMID: 34898694.

    Read At: PubMed

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