Josee Dupuis, PhD

Professor, Biostatistics
Josee Dupuis
(617) 638-5880dupuis@bu.edu
Crosstown Center – CT321
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Biography

Josée Dupuis, Ph.D, is a Professor and Interim Chair of Biostatistics at Boston University School of Public Health. She previously held a faculty position at Northwestern University and more recently she was a senior statistical geneticist at Genome Therapeutics Corporation, a small biotech company. She has extensive experience in the development and application of methods for mapping complex traits. Her methodological work has included genome-wide significance level, mapping of quantitative traits in experimental organisms and robust quantitative trait linkage and association analysis methods in extended pedigrees. Her recent work involves the development of rare variant association tests in families, and approaches to detect gene x gene and gene x environment interactions. She is involved in the Framingham Heart Study, collaborating on projects to identify genes influencing diabetes related traits, pulmonary function and biomarkers of inflammation. She is a co-instructor for BS858 (Introduction to Statistical Genetics) in the Fall, and teaches BS860 (Statistical Genetics II) in the spring semester of even years.

Other Positions

  • Interim Chair of Biostatistics, Biostatistics, Boston University School of Public Health
  • Member, Bioinformatics Graduate Program, Boston University

Education

  • Stanford University, PhD
  • Stanford University, MS
  • Concordia University, BS

Classes Taught

  • SPHBS715
  • SPHBS858
  • SPHBS860
  • SPHBS901
  • SPHBS980
  • SPHBS980

Publications

  • Published on 7/1/2016

    Ho JE, Gao W, Levy D, Santhanakrishnan R, Araki T, Rosas IO, Hatabu H, Latourelle JC, Nishino M, Dupuis J, Washko GR, O'Connor GT, Hunninghake GM. Galectin-3 Is Associated with Restrictive Lung Disease and Interstitial Lung Abnormalities. Am J Respir Crit Care Med. 2016 Jul 1; 194(1):77-83. PMID: 26771117.

    Read at: PubMed
  • Published on 5/4/2016

    Raghavan S, Pachucki MC, Chang Y, Porneala B, Fox CS, Dupuis J, Meigs JB. Incident Type 2 Diabetes Risk is Influenced by Obesity and Diabetes in Social Contacts: a Social Network Analysis. J Gen Intern Med. 2016 May 4. PMID: 27145760.

    Read at: PubMed
  • Published on 4/6/2016

    Hong J, Lunetta KL, Cupples LA, Dupuis J, Liu CT. Evaluation of a Two-Stage Approach in Trans-Ethnic Meta-Analysis in Genome-Wide Association Studies. Genet Epidemiol. 2016 May; 40(4):284-92. PMID: 27061095.

    Read at: PubMed
  • Published on 3/8/2016

    Wang S, Zhao JH, An P, Guo X, Jensen RA, Marten J, Huffman JE, Meidtner K, Boeing H, Campbell A, Rice KM, Scott RA, Yao J, Schulze MB, Wareham NJ, Borecki IB, Province MA, Rotter JI, Hayward C, Goodarzi MO, Meigs JB, Dupuis J. General Framework for Meta-Analysis of Haplotype Association Tests. Genet Epidemiol. 2016 Apr; 40(3):244-52. PMID: 27027517.

    Read at: PubMed
  • Published on 2/23/2016

    Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, Choi S, Chen H, Kaur I, Takeuchi F, Fontanillas P, Thuillier D, Yengo L, Below JE, Tam CH, Wu Y, Abecasis G, Altshuler D, Bell GI, Blangero J, Burtt NP, Duggirala R, Florez JC, Hanis CL, Seielstad M, Atzmon G, Chan JC, Ma RC, Froguel P, Wilson JG, Bharadwaj D, Dupuis J, Meigs JB, Cho YS, Park T, Kooner JS, Chambers JC, Saleheen D, Kadowaki T, Tai ES, Mohlke KL, Cox NJ, Ferrer J, Zeggini E, Kato N, Teo YY, Boehnke M, McCarthy MI, Morris AP. Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Hum Mol Genet. 2016 Feb 23. PMID: 26911676.

    Read at: PubMed
  • Published on 2/16/2016

    Leong A, Porneala B, Dupuis J, Florez JC, Meigs JB. Type 2 Diabetes Genetic Predisposition, Obesity, and All-Cause Mortality Risk in the U.S.: A Multiethnic Analysis. Diabetes Care. 2016 Apr; 39(4):539-46. PMID: 26884474.

    Read at: PubMed
  • Published on 2/16/2016

    Putman RK, Hatabu H, Araki T, Gudmundsson G, Gao W, Nishino M, Okajima Y, Dupuis J, Latourelle JC, Cho MH, El-Chemaly S, Coxson HO, Celli BR, Fernandez IE, Zazueta OE, Ross JC, Harmouche R, Estépar RS, Diaz AA, Sigurdsson S, Gudmundsson EF, Eiríksdottír G, Aspelund T, Budoff MJ, Kinney GL, Hokanson JE, Williams MC, Murchison JT, MacNee W, Hoffmann U, O'Donnell CJ, Launer LJ, Harrris TB, Gudnason V, Silverman EK, O'Connor GT, Washko GR, Rosas IO, Hunninghake GM. Association Between Interstitial Lung Abnormalities and All-Cause Mortality. JAMA. 2016 Feb 16; 315(7):672-81. PMID: 26881370.

    Read at: PubMed
  • Published on 2/10/2016

    Willems SM, Cornes BK, Brody JA, Morrison AC, Lipovich L, Dauriz M, Chen Y, Liu CT, Rybin DV, Gibbs RA, Muzny D, Pankow JS, Psaty BM, Boerwinkle E, Rotter JI, Siscovick DS, Vasan RS, Kaplan RC, Isaacs A, Dupuis J, van Duijn CM, Meigs JB. Association of the IGF1 gene with fasting insulin levels. Eur J Hum Genet. 2016 Feb 10. PMID: 26860063.

    Read at: PubMed
  • Published on 1/13/2016

    Kan M, Auer PL, Wang GT, Bucasas KL, Hooker S, Rodriguez A, Li B, Ellis J, Adrienne Cupples L, Ida Chen YD, Dupuis J, Fox CS, Gross MD, Smith JD, Heard-Costa N, Meigs JB, Pankow JS, Rotter JI, Siscovick D, Wilson JG, Shendure J, Jackson R, Peters U, Zhong H, Lin D, Hsu L, Franceschini N, Carlson C, Abecasis G, Gabriel S, Bamshad MJ, Altshuler D, Nickerson DA, North KE, Lange LA, Reiner AP. Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project. Eur J Hum Genet. 2016 Aug; 24(8):1181-7. PMID: 26757982.

    Read at: PubMed
  • Published on 1/1/2016

    Wang S, Hu FB, Dupuis J. The Genetics of Type 2 Diabetes and Related TraitsBiology, Physiology and Translation. Editor: Florez JC. Type 2 Diabetes Prediction. Springer. New York. 2016; 425-440.

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