Josée Dupuis
Profiles

Josee Dupuis, PhD

Adjunct Professor, Biostatistics - Boston University School of Public Health

617-358-2517
dupuis@bu.edu
Crosstown Center - 324
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Biography

Josée Dupuis, Ph.D, is an adjunct Professor of Biostatistics at Boston University School of Public Health (BUSPH). She was previously Chair of Biostatistics at BUSPH. She has held a faculty position at Northwestern University and a senior statistical geneticist position at Genome Therapeutics Corporation, a small biotech company. She has extensive experience in the development and application of methods for genome-wide association studies, gene by environment interaction investigation, genetic meta-analysis and rare variant analysis, with special emphasis on the development of novel statistical approaches to analyze genetic data collected on large families. She is involved in the Framingham Heart Study, collaborating on projects to identify genes influencing diabetes related traits and pulmonary function traits.

Other Positions

  • Investigator - Framingham Heart Study
  • Member, Bioinformatics Graduate Program - Boston University
  • Member, Genome Science Institute - Boston University

Education

  • Stanford University, PhD Field of Study: Statistics
  • Stanford University, MS Field of Study: Statistics
  • Concordia University, BS Field of Study: Statistics

Websites

Publications

  • Published on 4/23/2026

    Peloso GM, Wang D, Abbruzzese SM, Bis JC, Choi SH, Beiser A, Bressler J, Dupuis J, Fohner AE, Ghanbari M, Gibbs RA, Heard-Costa N, Ikram MA, Lacaze P, Le Grand Q, Lopez OL, Mosley TH, Riaz M, Soumaré A, Yaqub A, Boerwinkle E, Psaty BM, Fornage M, Seshadri S, DeStefano AL. Whole genome sequencing analysis of over 3500 individuals dementia-free over 85 years old. J Alzheimers Dis. 2026 Apr 23; 13872877261444302. PMID: 42024100.

     Read At: PubMed
  • Published on 4/9/2026

    Aggarwal M, Joehanes R, Huan T, Courchesne P, Dupuis J, O'Connor G, Levy D. Integrative Proteomic Profiling of Blood Pressure and Hypertension. Hypertension. 2026 Apr 09. PMID: 41953991.

     Read At: PubMed
  • Published on 3/24/2026

    St-Pierre J, Kang J, Nagy C, Fiori L, Turecki G, Dupuis J, Bhatnagar SR, Orri M. A genome-wide investigation of depression among individuals with and without irritability. Mol Psychiatry. 2026 Mar 24. PMID: 41872521.

     Read At: PubMed
  • Published on 2/28/2026

    Patchen BK, Zhang J, Gaddis N, Bartz TM, Chen J, Debban C, Leonard H, Nguyen NQH, Seo J, Tern C, Allen R, DeMeo DL, Fornage M, Melbourne C, Minto M, Moll M, O'Connor GT, Pottinger T, Psaty BM, Rich SS, Rotter JI, Silverman EK, Stratford J, Zhang C, Barr RG, Cho MH, Gharib SA, Manichaikul A, North K, Oelsner EC, Simonsick EM, Tobin MD, Yu B, Choi SH, Dupuis J, Cassano PA, Hancock DB. Multi-ancestry genome-wide association study and meta-analysis of lung function decline. Respir Res. 2026 Feb 28; 27(1). PMID: 41764487.

     Read At: PubMed
  • Published on 2/21/2026

    Zhang J, Moll M, Debban CL, Hobbs BD, Rijhwani H, Washko GR, Celli BR, Silverman EK, Bakke P, Oelsner EC, Barr RG, Agustí A, Faner R, Bruselle GG, Humphries SM, Lynch DA, Dupuis J, Manichaikul AW, O'Connor GT, Cho MH. BMI-Related Genetic Factors and COPD Imaging Phenotypes. Ann Am Thorac Soc. 2026 Feb 21. PMID: 41721747.

     Read At: PubMed
  • Published on 2/6/2026

    Djelmami-Hani R, Adebile T, Zhao R, Kwakyi E, Amira O, Omotoso B, Mamven M, Raji YR, Solarin A, Umeizudike T, Eduful E, Olokode BF, Ripiye N, Oluwadare T, Braimoh R, Ijoma C, Mumuni AA, Cozier Y, Quintiliani L, Arogundade F, Salako B, Parekh R, Gbadegesin RA, Dupuis J, Ulasi I, Adu D, Ojo A, Waikar S, Mitchell D, Anderson C, Ilori TO. Beverage patterns, blood pressure, and proteinuria among West Africans with chronic kidney disease: a cross-sectional analysis of the diet, CKD, and apolipoprotein L1 study. Front Nutr. 2026; 13:1724375. PMID: 41727202.

     Read At: PubMed
  • Published on 1/14/2026

    Li J, Hu J, Yun H, Mei Z, Wang X, Luo K, Guasch-Ferré M, Han X, Truong B, Merino J, Jia C, Ruiz-Canela M, Rebholz CM, Moon EH, Alkis T, Liu G, Yao J, Zhang X, Porneala BC, Salas-Salvadó J, Wang TJ, Dupuis J, Selvin E, Guo X, Bhupathiraju SN, Brody JA, Liu Y, Wood AC, North KE, Jung SY, Liu CT, Sotoodehnia N, Liu S, Tinker LF, Eliassen AH, Manson JE, Florez JC, Gerszten RE, Clish CB, Liang L, Lemaitre RN, Tucker KL, Rich SS, Rotter JI, Martínez-González MA, Rexrode KM, Meigs JB, Boerwinkle E, Kaplan RC, Hu FB, Yu B, Qi Q. Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes. Nat Med. 2026 Feb; 32(2):660-670. PMID: 41535386.

     Read At: PubMed
  • Published on 12/9/2025

    Wang N, Zhang Y, Schroeder P, Huerta-Chagoya A, Mandla R, Meigs JB, Manning AK, Liu CT, Dupuis J, Mercader JM. Evaluation of Sex-Stratified Polygenic Risk Scores for Type 2 Diabetes Mellitus and Glycemic Traits in the Framingham Heart Study. Diabetes Metab J. 2025 Dec 09. PMID: 41360390.

     Read At: PubMed
  • Published on 11/28/2025

    Sevilla-González M, Wang N, Hanson PA, Bebo A, Hitchcock D, Hsu S, Westerman KE, Cromer SJ, Barry VG, Borns-Weil Y, Zhang Y, Ben-Yossef O, Patel CJ, Franceschini N, Taylor KD, Ávila-Pacheco J, Clish CB, Gertzen RE, Raffield LM, Kooperberg C, Rich SS, Dupuis J, Rotter JI, Liu CT, Meigs JB, Manning AK. Dissecting Genetic and Environmental Determinants of Plasma Molecular Signatures and Their Link to Type 2 Diabetes Risk. medRxiv. 2025 Nov 28. PMID: 41358287.

     Read At: PubMed
  • Published on 11/17/2025

    Goldman-Pham R, Alter MP, Bao R, Collins SÉ, Debban CL, Allinson JP, Ambler A, Bertoni AG, Caspi A, Lovinsky-Desir S, Ekstrom MP, Engert JC, Jacobs DR, Malinsky D, Manichaikul A, Michos ED, Moffitt TE, Oelsner EC, Ramrakha S, Rich SS, Sack C, Stanojevic S, Subbarao P, Sugden K, Theodore R, Watson KE, Williams B, Yang B, Dupuis J, Shaheen SO, Barr RG, Hancox RJ, Smith BM. Quantifying the impact of early life growth adversity on later life health. Commun Med (Lond). 2025 Nov 17; 5(1):534. PMID: 41258496.

     Read At: PubMed

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