Ian M. Sanne, MBBCH
Adjunct Associate Professor, Global Health - Boston University School of Public Health
Biography
Professor Ian Matthias Sanne is a South African born infectious diseases doctor and has been involved in HIV and TB research since qualifying as internist in 1996. Since 2003 he has led the Wits HIV Research Group Clinical Trials Unit, and from 2003- 2012 led the Adult Treatment Research Site. He currently holds the AIDS Clinical Trials Group International Vice-Chair position and is responsible for overseeing the network’s research at 25 international sites in 13 countries and assisting in the prioritization of the research agenda. The focus of his research attention is an integrated program of HIV and TB research from prospective phase I-IV clinical trials, conducted predominantly through international collaborations with the NIH, EDCTP, Global TB Alliance and the Medical Research Council of South Africa. The key focus in the ACTG collaboration is prospective research to inform diagnostic, prevention and treatment interventions to optimize the diagnosis and treatment of HIV and tuberculosis. In addition through programs of implementation sciences and monitoring evaluation data produced as part of the Right to Care PEPFAR implementation program epidemiologic and health economic evaluation of health care interventions. The overall aim is to develop evidence based health system strengthening interventions to address the public health emergencies facing the resource poor setting. At the intersection of clinical care, and clinical trial administration, Professor Sanne continues to provide expertise to the ACTG leadership from the experience gained as the founding Director and Chief Executive Officer of Right to Care.
Education
- University of the Witwatersrand, MBBCh Field of Study: Medicine-Surgery
- University of the Witwatersrand, DTM&H
Publications
- Published on 2/12/2024
Pisa P, Kinge CW, Chasela C, Mothibi E, Thaung YM, Thwin HT, Aung NM, Chew KW, Gandhi MM, Clint C, Minior T, Lwin AA, Freiman MJ, Kyi KP, Sein YY, Marange F, van der Horst C, Mohamed S, Barralon M, Sanne I. Evaluation of GeneXpert and advanced biological laboratories UltraGene HCV diagnostic detection and performance against Roche real time PCR in Myanmar. J Clin Virol. 2024 Apr; 171:105653. PMID: 38408420.
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- Published on 2/1/2024
Jassat W, Mudara C, Ozougwu L, Welch R, Arendse T, Masha M, Blumberg L, Kufa T, Puren A, Groome M, Govender N, Pisa P, Govender S, Sanne I, Brahmbhatt H, Parmley L, Wolmarans M, Rousseau P, Selikow A, Burgess M, Hankel L, Parker A, Cohen C. Trends in COVID-19 admissions and deaths among people living with HIV in South Africa: analysis of national surveillance data. Lancet HIV. 2024 Feb; 11(2):e96-e105. PMID: 38296365.
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- Published on 1/25/2024
Takalani A, Robinson M, Jonas P, Bodenstein A, Sambo V, Jacobson B, Louw V, Opie J, Peter J, Rowji P, Seocharan I, Reddy T, Yende-Zuma N, Khutho K, Sanne I, Bekker LG, Gray G, Garrett N, Goga A. Safety of a second homologous Ad26.COV2.S vaccine among healthcare workers in the phase 3b implementation Sisonke study in South Africa. Vaccine. 2024 Feb 27; 42(6):1195-1199. PMID: 38278629.
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- Published on 4/17/2023
Jassat W, Abdool Karim SS, Ozougwu L, Welch R, Mudara C, Masha M, Rousseau P, Wolmarans M, Selikow A, Govender N, Walaza S, von Gottberg A, Wolter N, Terrence Pisa P, Sanne I, Govender S, Blumberg L, Cohen C, Groome MJ. Trends in Cases, Hospitalizations, and Mortality Related to the Omicron BA.4/BA.5 Subvariants in South Africa. Clin Infect Dis. 2023 Apr 17; 76(8):1468-1475. PMID: 36453094.
Read At: PubMed
- Published on 3/23/2023
Jacobson BF, Schapkaitz E, Takalani A, Rowji PF, Louw V, Opie J, Bekker LG, Garrett N, Goga A, Reddy T, Zuma NY, Sanne I, Seocharan I, Peter J, Robinson M, Collie S, Khan A, Takuva S, Gray G. Vascular thrombosis after single dose Ad26.COV2.S vaccine in healthcare workers in South Africa: open label, single arm, phase 3B study (Sisonke study). BMJ Med. 2023; 2(1):e000302. PMID: 37063238.
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- Published on 2/8/2023
Pettit AC, Phillips PPJ, Kurbatova E, Vernon A, Nahid P, Dawson R, Dooley KE, Sanne I, Waja Z, Mohapi L, Podany AT, Samaneka W, Savic RM, Johnson JL, Muzanyi G, Lalloo UG, Bryant K, Sizemore E, Scott N, Dorman SE, Chaisson RE, Swindells S. Rifapentine With and Without Moxifloxacin for Pulmonary Tuberculosis in People With Human Immunodeficiency Virus (S31/A5349). Clin Infect Dis. 2023 Feb 08; 76(3):e580-e589. PMID: 36041016.
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- Published on 12/8/2022
Mekota AM, Gillespie SH, Hoelscher M, Diacon AH, Dawson R, Churchyard G, Sanne I, Minja L, Kibiki G, Maboko L, Lakhi S, Joloba M, Alabi A, Kirenga B, McHugh TD, Grobusch MP, Boeree MJ. Building sustainable clinical trial sites in Sub-Saharan Africa through networking, infrastructure improvement, training and conducting clinical studies: The PanACEA approach. Acta Trop. 2023 Feb; 238:106776. PMID: 36502888.
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- Published on 11/17/2022
Antoniak S, Chasela CS, Freiman MJ, Stopolianska Y, Barnard T, Gandhi MM, Liulchuk M, Tsenilova Z, Viktor T, Dible J, Wose Kinge C, Akpan F, Minior T, Sigwebela N, Mohamed S, Barralon M, Marange F, Cavenaugh C, Horst CV, Antonyak S, Xulu T, Chew KW, Sanne I, Rosen S. Treatment outcomes and costs of a simplified antiretroviral treatment strategy for hepatitis C among Hepatitis C Virus and Human Immuno deficiency Virus co-infected patients in Ukraine. JGH Open. 2022 Dec; 6(12):894-903. PMID: 36514496.
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- Published on 9/23/2022
Moyo K, Igaba N, Wose Kinge C, Chasela C, Phohole M, Grove S, Makura C, Mudau L, Taljaard D, Rech D, Ramkissoon A, Searle C, Majuba P, Sanne I. Voluntary medical male circumcision in selected provinces in South Africa: Outcomes from a programmatic setting. PLoS One. 2022; 17(9):e0270545. PMID: 36149904.
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- Published on 7/27/2022
Benade M, Rosen S, Antoniak S, Chasela C, Stopolianska Y, Barnard T, Gandhi MM, Ivanchuk I, Tretiakov V, Dible J, Minior T, Chew KW, van der Horst C, Tsenilova Z, Sanne I. Impact of direct-acting antiviral treatment of hepatitis C on the quality of life of adults in Ukraine. BMC Infect Dis. 2022 Jul 27; 22(1):650. PMID: 35896987.
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