Tom Kepler

Tom Kepler is a professor of microbiology at the Boston University School of Medicine. Dr. Kepler’s laboratory develops computational tools and applies them in the context of systems-level experimentation to address outstanding questions in immunology and vaccine development. Much of their work is centered on antibodies and the cells (B cells) that produce them. Kepler, in partnership with colleagues at Duke and Harvard Universities, has developed a new approach to vaccination that uses computational methods to select combinations of immunogens to use in vaccines that drive affinity maturation in specific directions. These methods are being used to develop vaccines against HIV, influenza, and anthrax. Kepler received his PhD from Brandeis University and his BA from the University of Massachusetts Medical Center.