Primary Appointment Associate Professor, Department of Biomedical Engineering
Education A.M., Ph.D., Physics, Harvard University
B.S., Physics, B.S., Mathematics, University of California, Irvine
Additional Affiliations Division of Materials Science & Engineering
Areas of Interest Vascularization of biomaterials; quantitative physiology of engineered tissues; biomaterials for microsurgical applications; lymphatics; interstitial transport; inverse problems in vascular imaging; vascular biophysics; tumor-vessel interactions
Research Areas Dr. Tien and his group focus on the engineering of functional tissues through control of the cellular microenvironment. Of particular interest is the synthesis of microvascular networks that can serve as in vitro models of microcirculatory diseases or as ex vivo scaffolds for the perfusion of macroscopic tissues. Members of the group apply their understanding of fundamental biology to design structured biomaterials that orient, localize, or alter cellular interactions to elicit desired behavior. This work uses techniques adapted from molecular biology, surface chemistry, materials science, and lithography, and develops new technologies in-house as needed.