David J. Waxman, Ph.D.

Professor, (Biology, Medicine, BME)

Selected Recent Publications

  • Matthews BJ, Waxman DJ (2020) Impact of 3D genome organization, guided by cohesin and CTCF looping, on sex-biased chromatin interactions and gene expression in mouse liver. Epigenetics & Chromatin. 13:30. doi: 10.1186/s13072-020-00350-y. PMID: 32680543
  • Lau-Corona D, Bae WK, Hennighausen L, Waxman DJ. PLoS Genetics(2020) Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2. 16:e1008796. doi: 10.1371/journal.pgen.1008796. PMID: 32428001
  • Karri K, Waxman DJ (2020) Widespread dysregulation of long noncoding genes associated with fatty acid metabolism, cell division, and immune response gene networks in xenobiotic-exposed rat liver. Toxicol Sci. 174: 291-310. doi: 10.1093/toxsci/kfaa001. PMID: 31926019
  • Du B, Waxman DJ (2020) Medium dose intermittent cyclophosphamide induces immunogenic cell death and cancer cell autonomous type I interferon production in glioma models. Cancer Lett.470: 170-180. DOI: 10.1016/j.canlet.2019.11.025. PMID: 31765733.
  • Rampersaud A, Lodato NJ, Shin A, Waxman DJ (2019) Widespread epigenetic changes to the enhancer landscape of mouse liver induced by a specific xenobiotic agonist ligand of the nuclear receptor CAR. Toxicol Sci.171: 315-338. DOI: 10.1093/toxsci/kfz148. PMID: 31236583.
  • Melia T, Waxman DJ (2019) Sex-biased lncRNAs inversely correlate with sex-opposite gene coexpression networks in Diversity Outbred mouse liver. Endocrinology.160: 989-1007. DOI: 10.1210/en.2018-00949. PMID: 30840070.
  • Matthews BJ, Waxman DJ (2018) Computational prediction of CTCF/cohesin-based intra-TAD loopsthat insulate chromatin contacts and gene expression in mouse liver. Elife. PII: e34077. DOI: 10.7554/eLife.34077. PubMed  PMID: 29757144.
  • Wu J, Waxman DJ (2018) Immunogenic chemotherapy: Dose and schedule dependence and combination with immunotherapy. Cancer Lett.419: 210-221. DOI: 10.1016/j.canlet.2018.01.050. PubMed PMID: 29414305.
  • Hao P, Waxman DJ (2018) Functional roles of sex-biased, growth hormone-regulated microRNAs miR-1948 and miR-802 in young adult mouse liver. Endocrinology159: 1377-1392. DOI: 10.1210/en.2017-03109. PubMed PMID: 29346554.

Affiliation: Primary & Affiliated Faculty