Pharmacology & Experimental Therapeutics

  • GMS PM 701: Molecular & Translational Pharmacology
    This course provides an integrated sequence of interactive teaching sessions designed to educate students in the fundamental principles of pharmacology with an emphasis on modern translational approaches for drug discovery. Basic principles of pharmacokinetics, pharmacodynamics and pharmacogenomics, the properties of drug targets, and the chemistry of natural products, small molecules and proteins will be emphasized. Translational topics will include an in-depth considerations of systems-level effects of target-drug interaction, macromolecular modeling for drug design, and nanotechnological methods for drug delivery. 2 cr, Fall sem.
  • GMS PM 702: Molecular Neurobiology & Pharmacology
    Undergraduate Prerequisites: Consent of instructor - This course introduces the student to the principles of pharmacology in the context of neurobiology. Emphasis is placed on translational pharmacology and the application of pharmacology to therapeutics, particularly to neurological disorders. 2 cr, Spring sem.
  • GMS PM 710: Laboratory Techniques in Modern Pharmacology
    Graduate Prerequisites: consent of instructor - Supervised laboratory rotation emphasizing modern research techniques in molecular, cellular, and behavioral pharmacology. Problems of collection, summary, and interpretation of data are addressed. 2 cr, Fall & Spring sem.
  • GMS PM 730: Introduction to Medical Pharmacology
    Graduate Prerequisites: premedical courses in the sciences - Principles of pharmacology are covered and several major classes of therapeutic agents, with attention to their mechanisms of action. Issues of current and future concern in medical pharmacology are addressed including problems of drug abuse, the pricing of new drugs, and new biotechnological approaches to drug design and development. 4 cr, Spring sem.
  • GMS PM 801: Systems Pharmacology and Therapeutics I
    Graduate Prerequisites: consent of instructor - This course consists of lectures and discussions on the major classes of neuropharmacological agents, with special attention to systems mechanisms of therapeutic and adverse effects, including molecular, cellular, physiologic, psychological, and pathologic phenomenon. Starting from a basic review of current therapeutics in a particular disease area, students will be encouraged to anticipate new developments in the field and to propose solutions for solving problems with current pharmacologic approaches. 2 cr, Fall sem.
  • GMS PM 802: Systems Pharmacology and Therapeutics II
    Graduate Prerequisites: consent of instructor - This course consists of lectures and discussions on major classes of pharmacological agents, with special attention to systems mechanisms of therapeutics and adverse effects, including molecular, cellular, physiologic, psychological, and pathologic phenomenon. Starting from a basic review of current therapeutics in a particular disease area, students will be encouraged to anticipate new developments in the field and to propose solutions for solving problems with current pharmacological approaches. The course focuses on cardiovascular, endocrine, and steroid pharmacology and chemotherapy for inflammation, cancer, and bacterial and viral infections. 2 cr, Spring sem.
  • GMS PM 810: Current Topics in Pharmacological Sciences
    This course is given in conjunction with the weekly seminar program of the department. Students present and discuss research papers with the visiting scientist working in the cutting edge of pharmacology. 2 cr, Spring sem.
  • GMS PM 820: Behavior Pharmacology
    Graduate Prerequisites: consent of instructor. - This course examines the interaction between behavior and classes of drugs that affect the central nervous system. Emphasis is given to how behavioral studies assist understanding of mental disorders, including addictions, anxiety and mood disorders, pain syndromes, and dementia. Since discovering novel compounds for human neuropsychiatric diseases requires the development of valid and useful animal behavioral models for the specific disorder/domains under study, this course will address the current state of knowledge about animal models of mental illnesses and will focus on the neuropharmacological bases of these diseases. Faculty overview of a topic is followed by student-led discussion of an assigned research paper. 2 cr, Fall sem.n.
  • GMS PM 843: Pharmacologic Intervention in Inflammatory Responses
    Graduate Prerequisites: consent of instructor - Graduate Prerequisites: consent of instructor Course Description: Protective immunity is essential for maintaining the homeostasis of body, including the central nervous system and peripheral tissues. It is responsible for fighting against both host and pathogen, through detection of abnormal host condition (such as tumorigenesis, apoptosis, and necrosis) and pathogen invasion (such as microbes and allergic particles). The first responders to these changes are innate immune cells, such as neutrophils, dendritic cells and macrophages in the periphery and microglia and infiltrating myeloid cells in the central nervous system. The common response of innate immune cells is "acute inflammation." Although acute inflammation is a fundamental physiologic response of multicellular organisms to infection and injury, unresolved and chronic inflammation can have significant pathophysiologic consequences, such as gastrointestinal inflammation, neuroinflammation and tumor inflammation. This course examines the cellular components, inflammatory mediators, and their mechanisms of action, and therapeutic modulation of inflammation in the central nervous system and periphery. The format includes lectures on inflammatory components of selected diseases and student-led discussions of review and research papers. 2 cr, Fall sem.
  • GMS PM 881: Drug Discovery and Development
    Graduate Prerequisites: consent of instructor. - The Drug Discovery & Development is an advanced elective in Pharmacology. Lectures are given by industry scientists and incorporate real-world examples of drug development strategies and approaches that serve to reinforce the basic principles taught in the first-year pharmacology curriculum. The course provides students with an understanding of the process of drug development, specialized jobs in industry, how critical functions are integrated to develop a novel drug, and how key concepts in pharmacology are adapted to keep pace with biomedical research and technology. 2 cr, Fall sem.
  • GMS PM 892: Molecular and Neural Bases of Learning Behaviors
    Prereq: consent of instructor. Lectures and student presentations on literature in learning and memory research with special emphasis on integrated approaches from molecular, genetic, pharmacological levels to circuitry, systems, computational, and behavioral levels. Staff. 2 cr, Spring sem.
  • GMS PM 931: Research in Pharmacology
    Var cr
  • GMS PM 932: Research in Pharmacology
    Var cr