About

About the Center

The CTE Center is an independent academic research center located at Boston University School of Medicine. Part of the Boston University Alzheimer’s Disease Center (BU ADC), it was established in 1996 as one of 29 centers in the United States funded by the National Institutes of Health to advance research on Alzheimer’s disease and related conditions.

In collaboration with the VA Boston Healthcare System, and nonprofits including the Concussion Legacy Foundation (formerly known as the Sports Legacy Institute), and other NIH funded ADC Centers the CTE Center conducts high-impact, innovative research on chronic traumatic encephalopathy and other long-term consequences of repetitive brain trauma in athletes and military personnel.

Ann McKee, MD, Neuropathologist and Neurologist, is Director of the CTE Center. Dr. McKee also directs the Neuropathology Core of the Boston University ADC and directs all the brain banks at VA Boston Healthcare System, including the VA-BU-CLF brain bank and BU ADC brain bank. The neuropathologists, Thor Stein, MD, PhD, Bertrand (Russ) Huber MD, PhD and Victor Alvarez, MD  participate in the daily operations of the VA-BU-CLF brain bank and conduct neuropathological analyses and research for the CTE Center. Robert Stern, PhD directs the Clinical Research team. Michael Alosco, PhD and Jesse Mez, MD, PhD are active clinical researchers and participate in clinical neurological and neuropsychological data collection. Dr. Lee Goldstein, MD, PhD heads the molecular research team.

Research conducted at the CTE Center continues to lead the field in furthering the understanding of mild traumatic brain injury (mTBI) and Chronic Traumatic Encephalopathy (CTE). The VA-BU-CLF Brain Bank is the largest tissue repository in the world focused on traumatic brain injury (TBI) and CTE. The VA-BU-CLF Brain Bank contains more than 600 brains, including over 325 brains that have been diagnosed with CTE using the recently defined NINDS criteria for the diagnosis of CTE (6). Dr. McKee and her team of neuropathologists and other investigators have published a large number of studies focused on CTE (see below).

What is CTE?