Our Research

CTE Center research has played a major role in expanding our understanding of mild traumatic brain injury (TBI) and chronic traumatic encephalopathy (CTE) and  in changing public awareness about the dangers of repetitive head impacts, including concussion, subconcussion and blast-related injury. The CTE Center has been essential in establishing the neuropathological diagnostic criteria, developing a pathological staging scheme for the severity of CTE pathology, and delineating the clinicopathological correlations of CTE.

By furthering our knowledge of the long-term effects of traumatic brain injury and chronic traumatic encephalopathy, the overarching goal of the CTE Center is to create a safer environment for all contact sport athletes, military personnel and other individuals exposed to repetitive head impacts.

The CTE Center is currently focused on three interconnected research endeavors:

Molecular Research

The mission of the molecular research team is to discover disease mechanisms and develop new diagnostics and treatments for Chronic Traumatic Encephalopathy and other neurodegenerative disorders, including Alzheimer’s disease (AD).

VA-BU-CLF CTE Brain Bank

Pathological research is the bedrock of the study of disease. The CTE Center neuropathologists study brain and spinal cord tissue of former athletes to better understand the cause, progression, and characteristics of the disease.

Clinical Research

(DIAGNOSE & LEGEND studies)
The CTE Center will conduct and support research designed to identify genetic and environmental risk factors, diagnostic tests, treatment, and more.


If you are a researcher who wants to collaborate with the CTE Center, contact us.
The CTE Center is also affiliated with the Boston University Alzheimer’s Disease Center.