Research Track
Students who are interested in working in the pharmaceutical or biotech industries or those seeking a strong foundation for doctoral level studies in biology, physiology, or neuroscience, should select the MS in Human Physiology Research track. This program, typically completed in two-years of full-time study, includes a 16-credit thesis.
Thesis Requirement
To be considered for the research track, a candidate must select a suitable thesis topic and identify an adviser in the Department of Health Sciences who agrees to become the student’s academic adviser and first reader on the thesis. Your academic adviser will assist in identifying a topic for thesis research.
If the nature of the thesis project is such that an affiliation must be established with another laboratory or institution, arrangements between the Sargent College Department of Health Sciences and the external investigator or facility must be completed prior to initiation of the research. These arrangements include agreement of the external investigator to participate in research supervision and serve as the second reader. Thesis projects based outside of the Department of Health Sciences must be closely related with the ongoing research program or expertise of at least one Health Sciences faculty member with a full-time appointment. When this decision is finalized between the student and the faculty member, the program director should be notified so the student’s records can be updated.
After successfully completing a thesis project, a candidate must present it orally in a session open to the public.
The thesis committee will consist of two members who are involved in and/or are knowledgeable about the thesis topic area. At least one must be a full-time member of the Human Physiology Department faculty.
Steps for Completing a Thesis
- Plan project with adviser
- Thesis proposal meeting (with committee members)
- Data collection
- Data analysis
- Oral presentation
- Submission of written thesis
BU’s Mugar Library has published a comprehensive Guide for Writers of Theses and Dissertations. These instructions should be carefully studied before initiating preparation of your thesis.
Curriculum
Core Courses
SAR HS750: The Physiologist's Toolbox
Undergraduate Prerequisites: Course in biology, cell biology or physiology, and consent of instruct or. Master and doctoral students only. - This course will cover the skills beyond benchwork that are necessary to be a competitive physiologist. The classes will be a mix of didactic information and group discussion. Methodological issues covered will include study design, techniques used, interpretation of research findings and the process of peer reviewed publication. Practical experience in grant writing and scientific seminar presentation will be included. Students completing this course will understand the principles underlying preparation and publication of scientific manuscripts, grants and seminars and will be able to apply these principles as they read the scientific literature and participate in research projects related to thesis work. (Credits: 2)
SPH BS704: Introduction to Biostatistics
This course provides an overview of biostatistical methods, and gives students the skills to perform, present, and interpret basic statistical analyses. Topics include the collection, classification, and presentation of descriptive data; the rationale of estimation and hypothesis testing; analysis of variance; analysis of contingency tables; correlation and regression analysis; multiple regression, logistic regression, and the statistical control of confounding; sample size and power considerations; survival analysis. Special attention is directed to the ability to recognize and interpret statistical procedures in articles from the current literature. Students will use the R statistical package to analyze public health related data. * Can't be taken together for credit with SPH PH 717 (Credits: 3)
Plus 3 of the following
SAR HS538: Pathophysiology in Marginalized Individuals
PATHOPHYSIO MI (Credits: 4)
SAR HS541: Physiology Across the Lifespan
In this course we will explore physiological aspects of fetal development, birth, infancy, childhood, adolescence, adulthood and aging. Topics explored will include: bone and muscle development, physiology of common childhood diseases, the role of exercise and inactivity on bone, muscle and organ function, impact of stress across the lifespan, and the changes that occur during aging. (Credits: 4)
SAR HS542: Exercise Physiology
Undergraduate Prerequisites: (CASBI211 OR CASBI315) or consent of instructor - Application of physiological principles under different exercise conditions. Integration of the body systems in performance of exercise, work, and sports; immediate and long-range effects of these activities on the body. Laboratory includes the measurement of physiological parameters under extreme conditions. (Credits: 4)
SAR HS549: Mechanisms of Disruption in Brain Disorders
BRAIN DISORDERS (Credits: 4)
SAR HS572: Pulmonary Pathophysiology
How do humans breathe' How harmful are e-cigarettes to our body' What are the differences between an obstructive vs. a restrictive pulmonary disease' In Pulmonary Pathophysiology we will discuss these questions and more, developing an understanding of the physiological mechanisms underlying the function of the pulmonary system in health and disease. Through group discussion, active learning activities, and the creation of short films in small groups, we will take an in-depth look into the current understanding of pulmonary pathophysiology. (Credits: 4)
SAR HS575: Cardiovascular Pathophysiology
Undergraduate Prerequisites: (CASBI211 OR CASBI315) - Overview of anatomy and physiology of the cardiovascular systems during normal and pathological conditions. This course will also cover pathophysiology of exercise performance in cardiovascular diseases, as well as adaptations to physical conditioning. (Credits: 4)
SAR HS576: Clinical Measurements in Cardiology
CLINMSMT CARDIO (Credits: 4)
SAR HS581: Gross Human Anatomy
Undergraduate Prerequisites: CASBI105 & CASBI106 or CASBI107 & CASBI108 and CASBI211 or CASBI315 - Regional approach to the musculoskeletal, peripheral nervous, and circulatory systems of the human body. Laboratories reinforce the lectures by a study of osteology, prosected cadavers and live anatomy palpations. Either semester. (Credits: 4)
SAR HS582: Neuroanatomy and Neurophysiology
Undergraduate Prerequisites: (CASBI211 OR CASBI315) SARHS369 recommended. - Lecture and laboratory related to the detailed study of the development, morphology, internal configuration, functions, and pathological deficits of the peripheral and central nervous system in humans. Spring semester only. (Credits: 4)
SAR HS592: Muscle Physiology
Undergraduate Prerequisites: college-level physiology. - Advanced study of skeletal muscle properties. The regulation and adaptive capacity of muscle properties are examined through study of muscle fiber types, regeneration, injury, disuse, and strengthening and endurance activities. Scholarly exchange is essential. (Credits: 4)
SAR HS652: Advanced Exercise Physiology
This upper-level course will provide an in-depth exploration of the physiological responses and adaptations to acute and chronic exercise. Building upon foundational knowledge, Advanced Exercise Physiology combines theoretical concepts with practical applications, emphasizing critical analysis of current research and hands-on laboratory experiences. Over the semester we¿ll engage in discussions intended develop a comprehensive understanding of how exercise physiology is applied in real-world contexts. Topics covered include: exercise metabolism, cardiorespiratory adaptations, neuromuscular adaptations, environmental impacts, and fitness assessment. (Credits: 4)
SAR HS745: Seminar: Advanced Regional Anatomy
Graduate Prerequisites: SAR HS369, CAS BI315 or BI211 and consent of instructor. - Investigation-based independent course examining the visceral anatomy of two cadavers. The course begins with instruction in dissection techniques, then full dissection of two cadavers is performed. Based on the findings, students determine the cause of death of one of the cadaveric individuals and write a case report. Grading: 85 case report, 15 participation. (Credits: Var)
Total credit hours: 17
Thesis (16 credits)
SAR HS791: Directed Study and Research
Limited to students enrolled in the graduate human physiology or nutrition programs. - For MS students conducting research projects, including thesis work, under faculty guidance. (Credits: Var)
Total credit hours: 33 (Core Curriculum: 17 credits + Thesis: 16 credits)
Specialization
Options for specialized study or research are virtually unlimited. Here are some examples:
- Cellular and molecular physiology
- Cytoskeletal biology
- Mechanisms of neurodegenerative diseases
- Cardiovascular disease
- Manifestations of disease in marginalized populations
- Effects of aging on muscle physiology and function
- Cardiovascular and stress responses to environmental challenges
- Cognition and neural information processing
- Organization of the frontal cortex
- Exercise as a form of medicine for cancer patients
- Environmental exercise physiology
- Biomechanics