Professor Scott E. Schaus
CMD Co-PI and Associate Professor of Chemistry
Professor Schaus received his Ph.D. in Organic Chemistry with Eric N. Jacobsen at Harvard University in 1999 and did postdoctoral studies in Andy Myers’ laboratory at Harvard University as an NIH fellow. His research group concentrates on the synthesis of natural products, drawing mainly from catalytic methodologies as a source of selective organic transformations. Active projects in the group include the total synthesis of natural products that target cell cycle regulation, cell proliferation, and cell death. Recent developments in chemical and functional genomics make it possible to address specific questions concerning the biological response of cells to small molecule modulators. In this regard, genomic transcription profiling of both model organisms and mammalian cells using microarray technologies will be employed to validate drug targets and cellular response mechanisms.