Research Assistant Prof. Uwe Beffert and co-investigator Associate Prof. and Associate Chair of Neurobiology Angela Ho recently received a 5-year NIH grant to support the laboratory’s research on the genetic risk factor apolipoprotein E (apoE) and its role in Alzheimer’s disease. The $2.4 million grant will study the role of apoE and one of its receptors: apoER2, elucidating the functional roles of its many splice variants found in human brain. The preliminary data for this grant was generated through the generous support of the Harold and Margaret Southerland Alzheimer’s Research Fund, which was founded by David and Susan Caron to honor Susan’s late parents who both suffered from Alzheimer’s disease.