Age-related changes in muscle health at the cellular level
Understanding the underlying cellular mechanisms that explain muscle weakness and dysfunction in order to develop appropriate therapies that will prevent, retard, and reverse these age-related declines
Baumann, C.W., Kwak, D., Ferrington, D.A., and L.V. Thompson, Downhill exercise alters immunoproteasome content in mouse skeletal muscle. Cell Stress and Chaperones, 2017 Nov 9. doi: 10.1007/s12192-017-0857-y. [Epub ahead of print] PMID: 29124664
Liu, H., Ferrington, D.A., Baumann, C., and L.V. Thompson, Denervation-induced activation of the standard proteasome and immunoproteasome. PlosOne, 2016 Nov 22;11(11):e0166831. Doi: 10.1371/journal.pone.0166831 PMID: 27875560
Baumann, C., Liu, H.M., and L.V. Thompson, Denervation-induced activation of the ubiquitin-proteasome system reduces skeletal muscle quantity not quality. PLoS One, 2016 Aug 11;11(8):e0160839. Doi: 10.1371/journal.pone.0160839 PMID: 27513942
Baumann, C., Kwak, D., Liu, H., and L.V. Thompson, Age-induced oxidative stress: how does it influence skeletal muscle quantity and quality? J Appl Physiol, 2016 Nov 1;121(5):1047-1052. Doi: 10.1152/ japplphysiol.00321.2016. [Epub ahead of print] PMID: 27197856
Graber, T.G., Kim, J.H., Grange, R.W., McLoon, L.K., and L.V. Thompson, C57BL/6 Lifespan Study: Age-related declines in muscle power production and contractile velocity, AGE, June;37(3):9773. Doi:10.1007/s11357-9773-1. Epub 2015 Apr 17 PMID: 25893911
Graber, T.G., Ferguson-Stegall, L., Liu, H., and L.V. Thompson, Voluntary aerobic exercise reverses frailty in old mice. J Gerontol A Biol Sci Med Sci, 2015 Sep;70(9):1045-58. Doi:10.1093/Gerona/glu163. Epub 2014 Sep 30 PMID: 25271307
“Frailty: A call to action for physical therapists and scientists” Combined Sections Meeting, APTA, New Orleans, LA, February 2018.
“Fighting Sarcopenia and Frailty – One Protein at a Time”, University of Massachusetts-Amherst, December 2017; Colorado State University, Fort Collins, CO, September 2017
“Maintaining Cellular Homeostasis in Skeletal Muscle”, Gordon Research Conference, Biology of Aging, Les Diablerets, Switzerland, July 2017
“The Power of Animal Models to Discover the Biology of Aging”, International Association of Gerontology and Geriatrics (IAGG), San Francisco, CA, July 2017
“Frailty and Sarcopenia” – The Role of Protein Quantity and Quality”, University of Wisconsin, Madison, WI, April 2017
“Muscle Dysfunction and Frailty – The Role of Protein Quantity and Quality”, Cleveland Clinic, Cleveland, OH, January 2017
“Impact of Voluntary Exercise on Frailty in Old Mice”, APS Intersociety Meeting: The Integrative Biology of Exercise VII, Phoenix, AZ, November 2016
“Muscle Dysfunction and Frailty – The Role of Protein Quantity and Quality”, American Aging Association Annual Meeting, Seattle, WA, June 2016
“Fighting Frailty”, Inaugural Address for Research on Healthy Aging, School of Kinesiology, University of Minnesota, Minneapolis, MN May 2016
“Frailty and Sarcopenia: Of Mice and Men”, School of Gerontology, USC, Los Angeles, CA, January 2016
“Frailty: Of Mice and Men”, Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, January 2016
National Institutes on Aging (NIH), R24, Geroscience Network, Co-Investigator.
National Institute of Diabetes and Digestive and Kidney Diseases (NIH), R01, “Training Effects on Skeletal Muscle Lipid Dynamics,” Co-Investigator.
National Institutes on Aging (NIH), T32, “Training Program: Functional Proteomics of Aging,” Principal Investigator.
National Institutes on Aging (NIH), R01, “Quantitating Mitophagy in Skeletal Muscle Models,” Co-Investigator.
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH), P30AR066454, “Treatment of MD By Increased Angiogenesis,” Co-Mentor.
American Aging Association Fellow, June 2016
Marquette University Professional Achievement Award, April 2014
Gerontological Society of America Fellow, 2011
GSA Research Presentation highlighted in USA Today, Nov 21, 2010,
Ninth International Symposium on Neurobiology and Neuroendocrinology of Aging Travel Award, 2006
Brazilian Physical Therapy National Congress (COBRAF), Keynote Speaker, 2005
GRC-Biology of Aging Poster Award (oral presentation), France, 2004
GRC-Biology of Aging Travel Award, Ventura California, 2003
American Physical Therapy Association, Section on Geriatrics “Joan Mills Award,” 1999
NIA Workshop, Sarcopenia, Arlie, Virginia (selected attendee), 1994
Featured Researcher in PT Magazine of Physical Therapy, APTA, 1994
NASA Postdoctoral Fellowship, 1992
American Heart Association Pre-doctoral Fellowship, 1989 – 1991
Foundation for Physical Therapy Doctoral Scholarships, 1987 – 1991
Marquette University Graduate Fellowship, 1988
Awards and Honors
Catherine Worthingham Fellows of the American Physical Therapy Association, 2022
Denham Harman Award from the American Aging Association, 2022
Committee on Institutional Cooperation –Academic Leadership Program Fellow, University of Minnesota representative, 2013 – 2014
Women’s Faculty Cabinet – UofMN Medical School representative, 2010 – 2013
Mid-Career Women in Science – UofMN Medical School representative, 2003
Fesler-Lampert Chair in Aging Studies, Center on Aging Chair, 2000 – 2001
Early-Career Women in Science – UofMN Medical School representative, 1995
National Brookdale Fellowship on Aging – UofMN Candidate, 1994