• Kat J. McAlpine

    Editor, The Brink Twitter Profile

    Kat J McAlpine

    Kat J. McAlpine is editor of The Brink, Boston University’s news site for scientific breakthroughs and pioneering research. Kat has been telling science stories for over a decade, and prior to joining BU’s editorial staff, publicized research at Boston Children’s Hospital, Harvard University’s Wyss Institute for Biologically Inspired Engineering, and the University of Connecticut’s School of Engineering. Profile

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There are 29 comments on COVID Booster Shots: Everything You Need to Know

  1. GOOD INFO. I’m wondering how soon after after receiving the booster does peak immunity occur? Is it several weeks, as with the first shots, or does it happen more quickly?

  2. There is no place that says if you had covid last July and then six months later got two doses of the Moderna vaccine do you need a third shot or booster.

    1. I had breakthrough covid. After my 2 vaccines. I cant find info anywhere info on if a booster is needed or not in this situation.
      Thank you for this service. And info.

  3. This is the best and most informative information I have read for days about the booster and the vaccine! Thank you – after reading this I feel a bit more encouraged that those of us who are vaccinated will be doing well in the hard months ahead. Thank you to science and medicine !!

    1. Car molested vaccination in January as a health care worker. Just finished with Covid. Do I also need a booster.

      My wife finished vaccination in may. Got covid more likely from me. Worse symptoms too. Does she need a booster

  4. In order to get an effective immune response people who are immunocompromised need to get 3 doses as part of their primary vaccination series.
    After 6 months do they still need a fourth dose as a booster?

  5. I received my Pfizer booster and I’m anxious to hear about the Pfizer study as to what is the expected level of immunity percentages after the booster for infection/severe complications/death/break through infections, etc.. Can someone suggest where I might best find this info?
    I am also hoping to see a response to Paul’s question above as to when the expected peak immunity is reached after the booster.

    1. Just a sample of one, but I had a very strong reaction to the second dose. I was out flat the first day and it wasn’t until day 4 that I could function normally again.

      I had a 3rd dose a couple of days ago (6 months after dose #2). The evening of the shot my arm hurt, like it might from a flu shot. The next day I felt a little icky, as if I had had too much to drink the night before and then slept too little. I went about my day but as an afterthought checked my temp that evening – 99.8. Today I feel pretty much normal. So, bottom line, I did experience a reaction but nowhere near what I did the first time around.

      Apparently I’m officially considered immunocompromised because of strong chemo I received a few years ago but I don’t think my system reacts differently from the norm, I think I was just in the unlucky 1% that gets really, really sick from the vaccine. Still better than Covid!

    2. I got the booster 8/23. I’m immunocompromised. The 2nd dose, I was slightly tired and swollen at injection site and then I got a lump under my arm that hurt, but subsided after taking Ibuprofen. For the additional dose, I felt very icky. I was tired, but couldn’t sleep and never got a fever (I’m usually @ 97.0 and I got up to 98.1. I was feeling slightly nauseous. So, technically, it was a little worse than first time around (different), but still mild.

    1. I have the exact same question. I did not see a response to your question as to when can you get a booster if after being vaccinated you got the Delta Covid. Thank you.

  6. I received the Moderna first in December 2020 and the second vaccine Moderna in January 2021 I am a healthcare worker and just received my booster ….however when I return to the same hospital to get the booster it wasn’t until she was getting ready to give me the vaccine that she said and showed me OK here is the Pfizer 0.3 …. I told her that I got to previous Moderma and was it OK to mix with the booster ….they gave me a Pfizer booster… I know that the CDC has not recommended that but I was told by the hospital that they’re both MNRA and that it would be fine…Can you tell me if this is OK since on my vaccine card I now have two Moderna and one Pfizer booster …. And going forward in the years to come should I just continue to get Moderna? Thank you

  7. THIS IS A GREAT ARTICLE. IS THERE ANY DATA THAT SHOWS THERE IS AN ADVANTAGE TO GETTING THE OPPOSITE mRNA FROM YOUR ORIGINAL SERIES TO PROVIDE BROADER MECHANISMS OF IMMUNITY? I HAVE READ THAT “Too many doses of the same vaccine may mean that you are less protected when getting vaccinated against the mutants long term. This is called “original antigenic sin.” ARE THERE ANY MODIFIED mRNA VACCINES TO ADDRESS OTHER VARIANTS THAT ARE WORTH WAITING FOR? ALSO, WHAT MARKERS CORRELATE MOST WITH PROTECTION? AS A HEALTHCARE PROVIDER, I COMPLETED MY PFIZER SERIES ON FEB 8TH. I RECENTLY HAD IgG ANTIBODY TESTING WHICH INDICATED THAT I HAD NO ACTIVE ANTIBODIES. WHAT DOES THIS MEAN REGARDING MY PROTECTION AGAINST INFECTION? IS THERE ANY BETTER TEST TO SUGGEST YOUR LEVEL OF PROTECTION? SO I ASSUME I DEFINITELY NEED A BOOSTER BUT WHICH SHOULD I GET OR SHOULD I WAIT FOR A NEW VARIANT mRNA TO COME OUT? THANKS!!

  8. If you have an autoimmune disease are you more likely to get the Delta virus than someone with a good immune system? Will persons with an autoimmune disease be
    listed as a greater risk and be vaccinated sooner than those without?

  9. Thanks for the informative article.

    As noted, immunocompromised people, such as me, who were vaccinated with the J&J vaccine are left completely in the lurch. We cannot get a booster shot of any of the vaccines. In my case, I was on immunosuppression when I got the J&J vaccine. Three months later I got a blood test to see if I had any COVID antibodies — and I had none. Effectively I’m unvaccinated. My rheumatologist suggests I start all over by getting a series of one of the mRNA vaccines because I am off immunosuppression for now. But, no one is willing to vaccine me with one of the mRNA vaccines, leaving me wide open to COVID infection. I consider this a serious system failure of the FDA and CDC. It certainly is not patient centered. Suggestions appreciated!
    (BTW, recent evidence, not conclusive, is that Moderna will be better for immunocompromised individuals than Pfizer.)

    1. If you are considered immunocompromised, you can get them now. Consult your doctor. It’s not considered a booster for immunocompromised, it’s just an additional dosage. If you are not considered immunocompromised, then you’ll have to wait until it’s your time for the booster shot (8 months after 2nd dose of the initial series).

  10. I can’t seem to find any info about how soon the Booster actually “boosts” a vaccinated person’s immunity back to where it needs to be after 8 months. Will we need to wait weeks like we did with the 2 shots?

  11. I had my 3rd shot of Moderna Sept 6, 2021 and tested positive for covid Sept 14th. Had been to Dr on 13th for allergy symptoms. Was given steroid shot and Claritin. Next day realized food had no taste and went for test. Doing fine and never really felt bad. Guess 3 shots helped. I am 82 female

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