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    Kat J McAlpine

    Kat J. McAlpine is editor of The Brink, Boston University’s news site for scientific breakthroughs and pioneering research. Kat has been telling science stories for nearly a decade, and prior to joining BU’s editorial staff, publicized research at Boston Children’s Hospital, Harvard University’s Wyss Institute for Biologically Inspired Engineering, and the University of Connecticut’s School of Engineering. Profile

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There are 32 comments on How Light Turns Ordinary Hydrogen Peroxide into a MRSA Treatment

  1. Blue light has a wavelength range that is critical for this light to be called blue light! The devil is in the details when you are talking about the photon effect.
    Blue light range is 400-490 nm. What was the wavelength range of the LED light used?

  2. Very pleased to read that efforts are underway with a non-antibiotics approach. You might come up with application of light on surfaces susceptible to cause infection or be carrier of MRSA. Onset Some ayurvedic painkillers may also help calming down abscess & drain faster. Is hydrogen peroxide used in combination or separately at stage 2 of treatment?

    1. The light power and dosage applied is below the ANSI safety limit for exposure on human skin. In our study, we also haven’t observed any photo-damage on human cells. The phototherapy works selectively on MRSA as MRSA has staphyloxanthin molecule, the golden pigment, on its cell membrane and it is vulnerable to blue light.

  3. What might be interesting is the spectral absorption characteristic of the “Golden” color. Gold/yellow implies that every other wavelength other than yellow is absorbed – yellow being reflected.

    It begs the question of the spectral absorption characteristics of other bacteria . A feature of lasers is just how narrow they can be tuned. I do not wish to teach the Photomedicine group how to suck eggs.

    The flesh eating /necrotising bacteria would be another good target, as would some of the poisonous bite events proteins – the Stiletto snake for example.

  4. I have mrsa in my nostrils. How can I be treated with blue wavelength light? Before the diagnosis I was using benzoyl peroxide to treat the sores and it worked very well . I am on two antibiotics now. I was reluctant to try hydrogen peroxide just because of the tender tissue .

    1. Hi, Bill, thanks for sharing your info. Your condition can be potentially treated using a fiber-optic approach for light delivery. This application is under development now.

      1. I was diagnosed with methicillin staph aureus in my right ear in Dec 2008 ( just so happened to have had surgery a few months before this) I’ve now had it come back about 5 times since and I don’t understand why these doctors cannot prescribe the appropriate antibiotics for this resistant strain. I am so tired of dealing with this.

  5. What a great application of Science to help humanity! Understanding the bacteria, finding the key sites or weaknesses which can be used, targeting them by developing the treatment methods, Hats off to you!

  6. Jie, have you looked into using 222nm? There is research showing it kills MRSA 99.9% without the use of hydrogen peroxide and will not damage healthy skin cells. Also, what is the percentage solution of peroxide you used in the study and did you spray it directly into the open wound of mice or just in the culture? Thanks for the very important research result you have shared, super bugs are going to be the cause of an estimated 10million deaths world wide in the next 30 years!

    1. Thomas, thanks for your comments and suggestion. So far, we haven’t investigated the 222 nm light yet considering this wavelength is in the UV range. In the mice study, we applied 0.045% hydrogen peroxide solution directly into the would area.

  7. NH resident here, been fighting a recurrent mrsa infection for 3 years now. Where do I sign up to have these lasers shot into my nose and all over my body?

    1. Chris, we currently need to certain regulatory approval before we apply this novel phototherapy to human. The good news is that we are now working on it. If you are interested to be recruited in this study, please provide you contact info to me (email: jiehui@bu.edu) so we could reach you once we are ready. Best,
      Jie

  8. This is awesome. My 9yr old has been diagnosed with MRSA twice already this year and has eczema on his legs. Interested in knowing if this treatment might work for him, and where to buy the light and how long to apply. Thank you.

  9. Jie,
    Good afternoon. can the blue light be bought otc as long as it is 470nm? Also is there any recommendation on the lumens? My 9 yr old has contacted MRSA twice this year and we would like to see if this works in case we can’t get him into see his dr early enough. Thank you.

    1. Thomas, thanks for your great interest! We would really hope to help you. But further tests are needed before direct application on human. Thus far, we are planning a clinical trial to evaluate its safety and effectiveness, and also the treatment regimen. Once we finished these tests, we could be able to offer you more details. Please provide your contact info to me (email: jiehui@bu.edu) so we can keep you updated in the future. Thanks. Best, Jie

  10. Hi, so good to hear that someone is giving attention to this issue, i have been getting mrsa since 5 years and antibiotics doesn’t work at all. How can i get this light and hydrogen peroxide? Is there any link you can send us where we can buy these things and can you make a short video of the procedure so we can understand how to do it more effectively. We will then let you know how it worked and it will be helpfull for evidence. Thanks again for helping us.

    1. Supermarkets sell hydrogen peroxide for about a dollar. Peroxide, vinegar and baking soda reduced my infection considerably. Apply in that order. Just add some water to the baking soda to make a paste. Search on Amazon for blue laser. Meanwhile sunshine helps. God bless you.

    2. Sara, thanks for your great interest! We totally understand you feeling and that why we think our technotogy could be helpful. Before the direct application for human, we have to perform clinical test on human to further evaluate its safety, efficacy, and the treatment regimen or parameters. Once we got there, we are good to share with you about the treatment. Please provide us your contact info (my email, jiehui@bu.edu) so that we could keep you updated and could potentially recruit you in our test if you are interested. Thanks! Best, Jie

  11. I would absolutely love to join the study if at all possible. I have had a serious widespread MRSA infection over basically every part of my body for a year, very painful. Often five abscesses on my face. I have taken several rounds of antibiotics and although it seems my immunity has gone up and this last time i have had the most success yet, but if i get a cut or acne it still quickly turns into a problem area. I am very interested in finding alternative treatments because im pretty positive being given antibiotics too many times in my life and not taking them right is why I got MRSA in the first place. Since my faces is the main place i suffer from it, it has really really affected my life, self esteem, ability to get a job,

    1. Madeline, thanks for your great interest in our technology! We fully understand your suffer. We are now planning a clinical trail to evaluate its efficacy, safety, and the treatment regimen. Please provide your contact info to us (email, jiehui@bu.edu) so we could keep you updated. Thanks! Best, Jie

  12. It’s really a great thing to know that people are trying to treat diseases without antibiotics…
    Can you please explain the protocol used for this treatment.

    1. Dr. Samir, thanks for your great interest in our work! We have tested our photo-therapy approach both in vitro and in vivo in a animal skin model (detailed in this publication, https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201900030). We are now working on an IRB right to evaluate its efficacy on human patients and to further test the treatment regimen. Please let us know if you have more specific questions or any chance for collaboration. Best, Jie

  13. Good to see a antibiotic treatment for staph is being trialled as a NATUROPATH now retired i have varied sucess with treating staph your own immune system is the key to the problem natural products such as pure aloe vera gel ,bleach,coconut oil,tamanu oil certain ess oils have been effective correct formulae are critical to the problem i do not recommend self treatment without advice from a qualified professional who has worked in this field staph is a very serious infection to manage

  14. I have had MRSA for a long time and believe myself to be colonized I have taken several types of antibiotics be several times each to no avail.So is pulsing be blue Lazer the best light treatment? where would I purchase this?why was such a dilute peroxide used?how concentrated of a solution can be used without excessive cell damage?I have heard of h204 being taken internally at a few drops diluted in water to help heal body.has this approach been evaluated.I would be interested in participating in clinical trials and am emailing my contact info

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