2005

Akar H, Seldin DC, Magnani BJ, O’Hara C, Berk JL, Schoonmaker C, Cabral H, Dember LM, Sanchorawala V, Connors LH, Falk RH, Skinner M

Quantitative serum free light-chain assay in the diagnostic evaluation of AL amyloidosis. Amyloid: J Protein Folding Disorders, in press, 2005.

Akar H, Seldin DC, Magnani BJ, O’Hara C, Berk JL, Schoonmaker C, Cabral H, Dember LM, Sanchorawala V, Connors LH, Skinner M

Quantitative serum free light-chain assay in the diagnostic evaluation of AL amyloidosis. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 90-92, 2005.

Allan, L. L., and D. H. Sherr

Constitutive activation and environmental chemical induction of the aryl hydrocarbon receptor/transcription factor in activated human B lymphocytes. Mol Pharmacol 67:1740, 2005.

Berk JL, Grillone GA, Skinner M, Hartford AC

External beam radiation for tracheobronchial amyloidosis: The Boston University experience. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 463-465, 2005.

Brenner DA, Jain M, Wang B, Pimental DR, Connors LH, Skinner M, Apstein CS, Liao R

Human amyloidogenic light chains directly invoke oxidant stress and result in impaired cardiomyocyte function. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 145-147, 2005.

Bhatia J, Sanchorawala V, Seldin DC, Casserly LF, Berk JL, Falk RH, Skinner M, Dember LM

AL amyloidosis-associated hypothyroidism: prevalence and relationships to nephrotic syndrome. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 93-95, 2005.

Chung CM, Chiu JD, Connors LH, Gursky O, Lim A, Dykstra AB, Liepnieks J, Benson MD, Costello CE, Skinner M, Walsh MT

Thermodynamic stability of an I immunoglobulin light chain: relevance to multiple myeloma. Biophys J, 88: 4232-4242, 2005.

Connors LH, Prokaeva T, Akar H, Metayer M, Smith P, Lim A, Costello CE, Skinner M

Familial amyloidosis: recent novel and rare mutations in a clinical population. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp360-362, 2005.

Currier, N., S. Solomon, E. Demicco, D. Chang, M. Farago, H. Ying, I. Dominguez, A. Rogers, G. Sonenshein, R. Cardiff, J. Xiao, D. Sherr, and D. Seldin

Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors. Toxicologic Path, in press, 2005.

Dember LM
Emerging treatment approaches for the systemic amyloidoses. Kidney Int, 68: 1377-1390, 2005.

Dember LM, Stone JR

Case records of the Massachusetts General Hospital. Case 15-2005. An 80 year old man with shortness of breath, edema, and proteinuria. N Engl J Med, 342: 2111-2119, 2005.

Gertz MA, Comenzo R, Falk RH, Fermand JP, Hazenberg BP, Hawkins PN, Merlini G, Moreau P, Ronco P, Sanchorawala V, Sezer O, Solomon A, Grateau G

Definition of Organ Involvement and Treatment Response in Primary Systemic Amyloidosis (AL): A Consensus Opinion From the 10th International Symposium on Amyloid and Amyloidosis. Am J Hematology, 79: 319-328, 2005.

Hauck W, Dember LM, Hawkins PN, Hazenberg BPC, Skinner M, Bouwmeester MC, Briand R, Chicoine E, Gurbindo C, Hughes L, Garceau D

A prospective analysis of demography, etiology, and clinical findings of AA amyloidosis patients enrolled in the international clinical phase II/III Fibrillex study. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 179-181, 2005.

McComb ME, Lim A, Theberge R, Prokaeva T, Connors LH, Skinner M, Costello CE

Clinical diagnosis of familial transthyretin amyloidosis by automated data acquisition and processing with quadrupole orthogonal time-of-flight mass spectrometry. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 348-350, 2005.

Maecker, B., M. S. von Bergwelt-Baildon, D. H. Sherr, L. M. Nadler, and J. L. Schultze

Identification of a new HLA-A*0201-restricted cryptic epitope from CYP1B1. Int J Cancer 115:333, 2005.

Ng B, Connors LH, Davidoff R, Skinner M, Falk RH

Senile systemic amyloidosis presenting with heart failure. Arch Int Med, 165: 1425-1429, 2005.

Nordlinger M, Magnani BJ, Skinner M, Falk RH

B Natiuretic Peptide (BNP) as a marker of cardiac involvement in amyloidosis. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 88-90, 2005.

Oh, S. Y.; Ellenstein, A.; Chen, C.-D.; Hinman, J. D.; Berg, E. A.; Costello, C. E.; Yamin, R.; Neve, R. L.; Abraham, C. R.

Amyloid Precursor Protein Interacts with Notch Receptors. J. Neurosci. Res., in press, 2005.

Oran B, Malek K, Sanchorawala V, Wright DG, LaValley M, Quillen K, Finn KT, Skinner M, Seldin DC

Predictive factors for hematopoietic engraftment after autologous blood stem cell transplantation for AL amyloidosis. Bone Marrow Transplantation, 35: 567-575, 2005.

Prokaeva T, Ward JE, Fingar E, Kaut M, Smith P, O’Hara C, Connors LH, Skinner M, Seldin DC

Immunoglobulin (IG) light chain (LC) variable (VL) region genes demonstrate evidence for antigen selection in primary amyloidosis (AL). In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 43-45, 2005.

Ryu, H. Y., J. K. Emberley, J. J. Schlezinger, L. L. Allan, S. Na, and D. H. Sherr

Environmental chemical-induced bone marrow B cell apoptosis: death receptor-independent activation of a caspase-3 to caspase-8 pathway. Mol Pharmacol 68:1087, 2005.

Sanchorawala V, Seldin DC, Magnani BJ, Skinner M, Wright DG

Serum free light chain responses after high-dose intravenous melphalan and autologous stem cell transplantation for AL (primary) amyloidosis. Bone Marrow Transplantation, 36: 597-600, 2005.

Sanchorawala V, Wright DG, Quillen K, Kunz R, Finn KT, Malek K, Falk RH, Berk JL, Dember LM, Skinner M, Seldin DC

Treatment of AL amyloidosis with tandem cycles of high dose melphalan and autologous stem cell transplantation. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 124-126, 2005.

Seldin DC

The future of molecular diagnostics and targeted therapeutics in the amyloidoses. In: Sipe J, ed. Amyloid Proteins: The Beta Pleated Sheet Conformation and Disease, Wiley-VCH, pp 343-354, 2005.

Seldin DC, Sanchorawala V, Malek K, Wright DG, Quillen K, Finn KT, Falk RH, Berk JL, Dember LM, Wiesman J, Anderson J, Skinner M

High dose melphalan and autologous stem cell transplantation (HDM/SCT) for treatment of AL amyloidosis: ten year single institutional experience. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 160-162, 2005.

Seldin DC, Skinner M

Amyloidosis, In Kelly’s Textbook of Rheumatology, 7th edition, Ed by ED Harris, S Ruddy, CB Sledge, JS Sargent, RC Budd. Elsevier, Philadelphia, pp 1697-1704, 2005.

Theberge R, Jiang Y, Lim A, Connors LH, Ebehard J, Skinner M, Costello CE

Detection and characterization of post-translation modification in AL light chain proteins by mass spectrometry. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 46-48, 2005.

Trinkaus-Randall V, Walsh MT, Connors LH, Steeves S, Brenner D, Liao R, Eberhard J, Skinner M

Internalization of systemic amyloid light chains and heparan sulfate proteoglycan deposition. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp142-144, 2005.

Trinkaus-Randall V, Walsh MT, Steeves S, Monis G, Connors LH, Skinner M

Cellular response of cardiac fibroblasts to amyloidogenic light chains. Am J Path, 166: 197-208, 2005.

Walsh MT, Roskens V, Connors LH, Skinner M

Primary amyloidosis: conformational intermediates in immunoglobulin light chain proteins upon interaction with congo red under physiological conditions. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 40-42, 2005.

Ward JE, Brenner DA, Eberhard J, Liao R, Connors LH, O’Hara C, Seldin DC

In vitro and in vivo mouse models for AL amyloidosis. In Amyloid and Amyloidosis, Ed by G Grateau, RA Kyle, M Skinner, CRC Press, Boca Raton, pp 64-66, 2005.

Yang, X., D. Liu, T. Murray, G. Mitchell, D. Hestermann, S. Karchner, R. Merson, M. Hahn, and D. Sherr

The aryl hydrocarbon receptor constitutively represses c-myc transcription in human mammary tumor cells. Oncogene, in press, 2005.