Graduate Prerequisites: consent of instructor - The application of mass spectrometry to protein, glycoconjugate and carbohydrate structures has propelled developments in proteomics and functional genomics. This course describes how to use mass spectrometry to answer structural and functional questions in biomedical research. The course explores the background necessary to effectively design mass spectrometric (MS) experiments and interpret data. Students gain a full understanding of modern MS and its effective use in research. Lectures are devoted to instrumentation, ionization methods, applications to proteins, lipids, carbohydrates, glycoconjugates, nucleic acids and uses of the technology in proteomics, biotechnology and medicine. 2 cr, Spring sem.

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