Dr. Ravid’s research is focused on two interrelated projects that bear on mechanisms associated with the development of blood and vascular pathologies: (1) molecular mechanisms involved in cell cycle control during the development of bone marrow megakaryocytes into platelets, a process that includes cellular polyploidization prior to platelet fragmentation. Her group identified mechanisms of polyploidy in vascular smooth muscle cells, and found that the degree of polyploidy serves as an excellent biomarker for aging; (2) the role of vascular and bone marrow cell (progenitors and mature) adenosine receptors in vascular regeneration during injury or atherosclerosis. Her group uses transgenic and knockout models to assist in exploring mechanisms in vivo.
National Heart, Lung, and Blood Institute, RO1, “Adenosine Receptors and Atherogenesis,” Principle Investigator.
National Heart, Lung, and Blood Institute, T32, “Pre-Doctoral Training Program In Cardiovascular Biology,” Principle Investigator and Founder of an institutional Pre-Doctoral Training Program
National Heart, Lung, and Blood Institute, RO1, “Mechanisms Regulating Endomitosis in Megakaryocytes,”Principle Investigator.
Awards and Honors
2014 Weizmann Institute Visiting Professorship Award
2013 Department of Medicine Robert Dawson Evans Teaching Award, BU School of Medicine
2009 International Professor Fellowship Award, University of Sydney
2006 Educator of the Year Award, Graduate Medical Sciences, BU School of Medicine
2005 American Technion Society Patronage Award to Alumni Academicians
2005 Established Investigator Award, American Heart Association
1997 Grant-In-Aid Award for Young Investigators, American Heart Association
1986, 1987 Weizmann Postdoctoral Fellowship Award
1982 Gutwirth Prize for Outstanding Graduate Students, Technion, Israel Institute of Technology