• Additional Titles:Director, Cytoskeleton & Signaling Lab
  • Education:BS (Chemistry) College of Mt. St. Joseph
    PhD (Pharmacology) University of Cincinnati
  • Website or Lab: Cytoskeleton & Signaling Laboratory
  • Phone:617-353-7464

Scholarly Interests

  • Interactions between signaling proteins and cytoskeletal proteins, the differentiated smooth muscle cell; mechanisms of trafficking of signaling molecules; stroke, hypertension, pre-term labor.

Scholarly, Research, and/or Practice Interests

  • SAR HS750 Critical analysis of the Physiological Literature
  • SAR HP151 Introduction to the Health & Rehabilitation Professions

Selected Publications

Partial Bibliography at PubMed

Current Research Funding

2017-2022 NIH R01 AG053274, Principal Investigator “Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease”
2016-2017 NIH R56 AG053274, Principal Investigator “Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease”
2015-2017 NIH R21 AG050599, Principal Investigator “The Role of the Cytoskeleton in Vascular Aging”
2007-2012 NIH 1P01 HL86655 (1-5), Pincipal Investigator of P01, Project 1 and Core A “Dynamics of the Vascular Smooth Muscle Cytoskeleton”
2006-2011 NIH 1R01 HL080003(1-5), Principal Investigator “Subcellular Organization of Signaling in Smooth Muscle”
2005-2010 NIH 2R01 HL31704 (21-25), Principal Investigator “Regulation of Contraction and Growth of Blood Vessels”
2003-2009 NIH 1 R01 HD043054 (1-6), Principal Investigator “Signaling and Uterine Contractility during Pregnancy”

Current Editorial Responsibilities

2002- Editorial Board of American Journal of Physiology: Cell Physiology
2005- Editorial Board of Journal of Cellular and Molecular Medicine
2008- Guest Editor for Journal of Cellular and Molecular Medicine
2008- Editorial Board of Cell Health and Cytoskeleton

Awards and Honors

1975-1976 Ryan Fellow
1984-1989 American Heart Association Established Investigator
1992-1993 Wellcome Visiting Professor in the Basic Medical Sciences
1998- Fellow, Cardiovascular Section of the American Physiological Society
2006-2011 Honorary Faculty Fellow, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, UK

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