Former CMLD SAB Members

Dr. FRANK FANG

Dr. Fang received his B.S. degree in chemistry in (1983) from the University of Massachusetts at Amherst where he conducted undergraduate research with the late Professor Marvin D. Rausch. In 1989 Frank received his Ph.D. from Yale University working with Professor Samuel Danishefsky. From 1989-1991 Frank was a National Institutes of Health Postdoctoral Fellow in the laboratories of Professor Yoshito Kishi at Harvard University. From 1991-1997 Frank was a Senior Scientist, Research Investigator and Team Manager in Medicinal Chemistry and Chemical Development at Glaxo Research Institute and GlaxoWellcome in Research Triangle Park, North Carolina. From 1997 to present, Frank has been at Eisai Research Institute in Andover, Massachusetts where he is currently Senior Executive Director of Process Research & Development. Frank has served as a Reviewer on NIH SBIR Study Sections from 1999-2000. Frank was Vice-Chair and Chair of the 1998 and 2000 Gordon Conferences on Stereochemistry. Frank’s research interests include the total synthesis of biologically active natural product based drug candidates such as A58365A, porphycenes, camptothecins, aza-steroids, laulimalide, luminacins, zearalenones, and halichondrins

Dr. SAMUEL GERRITZ

Dr. Gerritz received his bachelor’s degree in chemistry in 1988 from the College of Wooster, where he conducted senior research with Professor Paul Gaus. He was an NSF Predoctoral Fellow at Massachusetts Institute of Technology and joined the group of the late Satoru Masamune. At M.I.T., Sam’s research focused on the total synthesis of Calyculin A. In 1993, Sam received his Ph.D. from M.I.T. and joined Glaxo in Research Triangle Park, North Carolina. During his tenure at Glaxo, Sam’s research focused on the application of combinatorial chemistry to ongoing drug discovery projects. In 2001, Sam moved to Bristol-Myers Squibb in Wallingford, Connecticut, as a Group Leader in the Lead Synthesis group. Sam serves on the editorial boards of the Journal of Combinatorial Chemistry andCurrent Topics in Medicinal Chemistry and is an adjunct professor at Quinnipiac University.

Professor SCOTT J. MILLER

Professor Miller received his B.A.(1989), M.A.(1989) and Ph.D.(1994) from Harvard University, and worked under Professor David Evans as a National Science Foundation Predoctoral Fellow. He later joined the California Institute of Technology as a National Science Foundation Postdoctoral Fellow under Professor Robert Grubbs. From 1996 to 2006, he served as a Professor of Chemistry at Boston College before joining the Chemistry Department at Yale University as a Professor of Organic Chemistry. Prof. Miller’s research program focuses on problems in asymmetric catalysis and synthesis. His efforts employ strategies that include catalyst design, the development of combinatorial techniques for catalyst screening, and the application of these approaches to complex molecule synthesis. Specific areas of interest include enantioselective acyl transfers, conjugate additions, phosphorylations, sulfations and carbon-carbon bond forming reactions.

Professor ERIC N. JACOBSEN

Professor Jacobsen obtained his B.S. degree in 1982 from NYU, where he carried out research in the laboratories of Professor Yorke Rhodes. His Ph.D. work was done at Berkeley in the field of organometallic chemistry under the direction of Bob Bergman, and he carried out postdoctoral studies from 1986 to 1988 as an NIH fellow at MIT with Barry Sharpless. In 1988, he began his independent career at the University of Illinois, where he was promoted to associate professor in 1991. He moved to Harvard University as full professor in the summer of 1993, and he was named the Sheldon Emory Professor of Organic Chemistry in 2001. He directs a research group of 20-25 graduate students and postdocs at Harvard, and his research interests lie in the discovery, mechanistic elucidation, and application of new reactions, with special emphasis on asymmetric catalytic processes.

Dr. JOHN C. (JACK) HODGES

Dr. Hodges completed his Bachelors degree in Chemistry at the University of Delaware and Doctorate in Medicinal Chemistry at the University of Arizona. After a two-year postdoctoral fellowship at the University of Rochester, he joined the pharmaceutical discovery effort at Parke-Davis in Ann Arbor, MI. He accumulated 21 years of experience as a drug discovery chemist before taking a position as Vice President of Chemistry at Berry & Associates, Inc., in Dexter, MI. Jack has been closely associated with the field of combinatorial chemistry, publishing numerous papers, including seminal articles on the topic of polymer-supported scavengers.

Professor BRYAN L. ROTH

Dr. B. Roth is currently a Professor in the Department of Pharmacology at the University of North Carolina School of Medicine and the Director of the Mental Health Psychoactive Drug Screening Program (NIMH-PDSP). Dr. Roth received his M.D./ Ph.D. in Biochemistry from St. Louis University Medical School and completed post-doctoral training in the Laboratory of Preclinical Pharmacology at the NIMH under the supervision of ‘Mimo’ Costa. Dr. Roth’s research is devoted to discovering how psychoactive compounds exert their actions at levels ranging from the most fundamental (e.g. atomic) to the most applied (e.g. human). Over the past two decades, Dr. Roth has contributed nearly 200 publications and has made major contributions to our understanding of GPCR structure and function, particularly related to CNS drug discovery.

Dr. GREGORY P. ROTH

Dr. G. Roth studied under the direction of Professor A. I. Meyers and received a Ph.D. in Chemistry from Colorado State University in 1988. Over the past 15 years has contributed to process, combinatorial and medicinal chemistry research programs at Bristol-Myers Squibb, Boehringer Ingelheim Pharmaceuticals, and Abbott Laboratories Bioresearch Center in Worcester, MA. He is presently an Associate Professor and Director of Medicinal Chemistry and Pharmacology at the Burnham Institute for Medical Research at Lake Nona, Florida.