Surya Pulukuri (Class of ’21)

Incorporating an Online Interactive Video Platform to Optimize Active Learning and Improve Student Accountability through Educational Videos Video learning holds an important place in modern STEM classrooms, but more improvements to the learning experience are needed. In order to introduce active-learning components into assignments, questions are often deployed alongside videos. Unfortunately, many students tend to […]

Larisa Kagermazova (Class of ’16), Yuekun Liu (Class of ’18), Milad Babaei (Class of ’21)

A Central Region of NF-κB Essential Modulator Is Required for IKKβ-Induced Conformational Change and for Signal Propagation NF-κB essential modulator (NEMO) regulates NF-κB signaling by acting as a scaffold for the kinase IKKβ to direct its activity toward the NF-κB inhibitor, IκBα. Here, we show that a highly conserved central region of NEMO termed the […]

Chen Sun (Class of ’16)

Square-planar Co(iii) in {O4} coordination: large ZFS and reactivity with ROS Oxidation of distorted square-planar perfluoropinacolate Co compound [CoII(pinF)2]2−, 1, to [CoIII(pinF)2]1−, 2, is reported. Rigidly square-planar 2 has an intermediate-spin, S = 1, ground state and very large zero-field splitting (ZFS) with D = 67.2 cm−1; |E| = 18.0 cm−1, (E/D = 0.27), g⊥ = 2.10, g‖ = 2.25 and χTIP = 1950 × 10−6 cm3 mol−1. This Co(III) species, 2, reacts […]

Emily Norwine (Class of ’18)

Dual oxidase/oxygenase reactivity and resonance Raman spectra of {Cu3O2} moiety with perfluoro-t-butoxide ligands A Cu(I) fully fluorinated O-donor monodentate alkoxide complex, K[Cu(OC4F9)2], was previously shown to form a trinuclear copper–dioxygen species with a {Cu3(μ3-O)2} core, TOC4F9, upon reactivity with O2 at low temperature. Herein is reported a significantly expanded kinetic and mechanistic study of TOC4F9 formation using stopped-flow spectroscopy. […]

Linda Zuckerman (Class of ’20)

Heterobimetallic {PtMn} and {PtFe} lantern complexes with exceptionally long metallophilic contacts A new series of heterobimetallic lantern complexes, [PtM(SAc)4(pySMe)] (M = Mn (1), Fe (2), Co (3), Ni (4), Zn (5)), as well as additions to the previously reported series, [PtM(SAc)4(pyNH2)] (M = Mn (6), Fe (7)), have been synthesized and thoroughly characterized. Notably, compounds 1 and 6 are the first crystallographically characterized, […]

Jeremy Weber (Class of ’16)

Luminescence of Lanthanide Complexes with Perfluorinated Alkoxide Ligands Four groups of rare-earth complexes, comprising 11 new compounds, with fluorinated O-donor ligands ([K(THF)6][Ln(OC4F9)4(THF)2] (1-Ln; Ln = Ce, Nd), [K](THF)x[Ln(OC4F9)4(THF)y] (2-Ln; Ln = Eu, Gd, Dy), [K(THF)2][Ln(pinF)2(THF)3] (3-Ln; Ln = Ce, Nd), and [K(THF)2][Ln(pinF)2(THF)2] (4-Ln; Ln = Eu, Gd, Dy, Y) have been synthesized and characterized. Single-crystal […]

Sydney Lagueux (Class of ’18)

Heterotrimetallic {LnOVPt} complexes with antiferromagnetic Ln–V coupling and magnetic memory The new PtVO(SOCR)4 lantern complexes, 1 (R = CH3) and 2 (R = Ph) behave as neutral O-donor ligands to Ln(OR)3 with Ln = Ce, Nd. Four heterotrimetallic complexes with linear {LnOVPt} units were prepared: [Ln(ODtbp)3{PtVO(SOCR)4}] (Ln = Ce, 3Ce (R = CH3), 4Ce (R = Ph); Nd, 3Nd (R = CH3), 4Nd (R = Ph); ODtbp = 2,6-ditertbutylphenolate). […]

Josh Nelson (Class of ’13)

Reversible PCET and Ambient Catalytic Oxidative Alcohol Dehydrogenation by {V=O} Perfluoropinacolate Complexes A new air-stable catalyst for the oxidative dehydrogenation of benzylic alcohols under ambient conditions has been developed. The synthesis and characterization of this compound and the related monomeric and dimeric V(IV)- and V(V)-pinF (pinF = perfluoropinacolate) complexes are reported herein. Monomeric V(IV) complex (Me4N)2[V(O)(pinF)2] (1) […]

Andrea Rustad (Class of ’19)

H-Activated Single Molecule Conductance and Binding Mechanism of Imidazole on Gold We identify imidazole as a pH-activated linker for forming stable single molecule–gold junctions with several distinct configurations and reproducible electrical characteristics. Using a scanning tunneling microscope break junction (STMBJ) technique, we find multiple robust conductance signatures at integer multiples of 1.9 × 10–2G0 and […]

Andrew Burwash (Class of ’18)

Molecular Insights into human hereditary apolipoprotein AI amyloidosis caused by the Glu34Lys mutation Hereditary apolipoprotein A-I (apoA-I) amyloidosis is a life-threatening incurable genetic disorder whose molecular underpinnings are unclear. In this disease, variant apoA-I, the major structural and functional protein of high-density lipoprotein, is released in a free form, undergoes an α-helix to intermolecular cross-β-sheet […]