Andrew Burwash (Class of ’18)

Molecular Insights into human hereditary apolipoprotein AI amyloidosis caused by the Glu34Lys mutation Hereditary apolipoprotein A-I (apoA-I) amyloidosis is a life-threatening incurable genetic disorder whose molecular underpinnings are unclear. In this disease, variant apoA-I, the major structural and functional protein of high-density lipoprotein, is released in a free form, undergoes an α-helix to intermolecular cross-β-sheet […]