COVID Booster Shots: Everything You Need to Know
Everything You Need to Know about COVID Booster Shots
BU epidemiologist explains why coronavirus vaccine boosters are necessary, whether they’ll protect against the Delta variant, more
How do booster shots work? Am I eligible for a COVID-19 booster shot? Why are these booster shots needed? What is the difference between a booster shot and a “third dose” for immunocompromised people? Will members of the Boston University community be able to get additional shots through the University’s vaccine clinic? People are looking for answers to these questions and to many more.
“Over time, even very effective vaccines wane in terms of how effective they are,” said Judy Platt, chair of BU’s Medical Advisory Group, cochair of the Vaccine Preparedness Group, and Student Health Services director, at the recent BU-wide town hall meeting August 19. “The same is true for our relatively new coronavirus vaccines.”
The Centers for Disease Control and Prevention has recommended a booster dose to enhance the efficacy of the Pfizer and Moderna vaccines, starting as soon as September 20 for individuals at least eight months after their second vaccine dose (it has not been recommended yet for the Johnson & Johnson vaccine).
Does that mean BU will begin offering boosters? Not so fast. Platt says BU hopes to offer the booster this fall, but right now the priority in August for the University’s vaccine clinics is to get people vaccinated who are not yet compliant with BU’s vaccine mandate. Beyond that, she says, if BU can acquire more doses of vaccines, then booster doses to the broader community could be offered.
Whether getting a booster shot will be mandatory for BU students, faculty, and staff as part of the University’s vaccine policy will be discussed, BU President Robert A. Brown said during the same August meeting. A booster mandate would be tricky because those shots have to be administered on a rolling basis, depending on when recipients completed their initial round of vaccination, he said.
To help answer common questions about the coronavirus booster shots, The Brink spoke with Cassandra Pierre, a Boston Medical Center associate hospital epidemiologist and medical director of public health programs. Pierre is also a BU School of Medicine assistant professor of medicine and chairs the school’s Diversity and Inclusion Advisory Council.
With Cassandra Pierre
The Brink: Why is the booster shot recommendation coming out only for the Pfizer and Moderna vaccines right now?
Pierre: The reason why it’s just coming out for the mRNA vaccines right now—both kinds made by Pfizer and Moderna—is because we have the greatest data for those mRNA vaccines, particularly regarding the waning of immunity of antibody levels after a period of six to eight months. We’re also hearing the CDC is making these recommendations based on real-world data, from urban areas, hospitals, and long-term care facilities. They’re really trying to align recommendations to evidence that’s available, although we have heard information will come in the next few weeks about the Johnson & Johnson vaccine. I really welcome that, because from an anecdotal perspective as well as from some studies, we worry potentially more about the waning protection against infection for individuals vaccinated with the Johnson & Johnson shot.
The Brink: We’ve heard that it is OK to mix and match Pfizer and Moderna vaccines to get the booster shot. But so far, the CDC has not recommended that it’s OK for people who first received a Johnson & Johnson vaccine to now get a Pfizer or Moderna booster shot. Why is this the case?
Pierre: I hope that scientific reticence will dissipate in the next few weeks. We do have information to show a really potent boosting with mixing vaccination strategies. Most of the data, I will say, are from looking at people who first received the AstraZeneca vaccine—which is made from the same technology that created the J&J vaccine—that really does show important boosting of the protective effect with an mRNA vaccine given as a second dose. There’s also potentially that benefit for J&J. Theoretically, I would love to give my patients who first got a J&J vaccine an mRNA booster shot. My prediction is that yes, we will soon be able to mix and match those vaccine strategies, but we need a little more data before we get to that guidance [from the CDC].
The other thing to keep in mind is that there is generally less robust data about J&J because there were far less people who got the J&J vaccine compared to people that received either Pfizer or Moderna. J&J was approved later in the game, so not only do we have fewer patients vaccinated, but by and large those people were vaccinated later.
The Brink: Based on the Pfizer and Moderna data that’s available, at what point do antibody levels seem to start diminishing?
Pierre: The data that I’ve seen, particularly for Pfizer, looked at antibody [levels] at six months after the second shot. They were declining at the six-month mark, but still seemed to be very good and elevated, and thought to still provide good protection against severe disease, hospitalization, and death.
The Brink: So why is the CDC’s recommendation to get vaccinated eight months after the second shot?
Pierre: It remains to be determined, and more data need to be distributed to all of us. We’ve heard [the CDC is factoring in] information about real-world protection, data coming from cities, hospitals, and long-term care centers. We’re still not seeing severe disease, hospitalization, and death six to eight months after people completed the second dose of their Pfizer or Moderna vaccines. The CDC also have said that they want to get out in front of waning immunity, to get people a booster shot before there’s a chance for immunity to falter enough to allow for severe infections. They want to get ahead of any declining immunity levels that might overwhelm our healthcare providers.
Additionally, there is some unpublished data (which has been referenced by experts including Anthony Fauci) indicating that the [eight-month] interval in the spacing of the booster may actually lead to longer-lasting, more durable immunity. They suggest we may not need another booster in quite some time (i.e., a period of years)…but we’ll have to wait and see.
The Brink: How do the booster shots work? The vaccine formulation for the Pfizer and Moderna shots hasn’t changed, so how much additional immunity does a booster shot give? Does it get people back up to the 90-plus percent effectiveness that was originally expected? Or does the immune system react less and less each time the vaccine is given?
Pierre: We know that the mRNA vaccines can give 94 or 95 percent protection after the first series of two shots, and a 98 percent reduction in severe complications. Both Pfizer and Moderna have done booster studies, and we know that Pfizer has submitted the results of the booster trial to the FDA, but we don’t yet know what those results say, but we do know those studies were conducted in areas of the US where the Delta variant was gaining hold. I do think the results of that trial will provide some answers to the questions you’ve asked.
The hope, though, is that because of the priming effect [of receiving the first two shots], it will allow the body’s immune system to react more aggressively to infection, to fight against any potential COVID infection. The immune-fighting cells have already been primed, so the theoretical concept—which we know happens with many other already FDA-approved vaccines like tetanus or whooping cough—is that the booster doses increase immunity over time.
The Brink: Are these booster shots going to turn into a regularly scheduled occurrence in the future?
Pierre: Many people have been speculating that we will need annual boosters for the COVID vaccines, and we have good precedents of other types of vaccines that require an annual booster. There is some thought that maybe there is a necessity to build out new mRNA vaccines to protect against other, new variants. Looking ahead, building new boosters will help us evade variants that may be more transmissible or cause severe disease or are able to evade the current vaccine.
The Brink: What’s the difference between a third shot for immunocompromised people and a “booster shot”?
Pierre: The third dose is meant to connote giving another dose of vaccine to individuals believed not to be able to sustain or produce an adequate immune response to the first two shots in the series. For them, that third shot is not a booster, but is a needed additional shot in their primary vaccination series to allow them to develop an effective immune response against severe infection and death. People who are less likely to mount an appropriate immune response are people on steroids, who have received organ transplants, have severe HIV infections, or other conditions.
The Brink: Have the majority of people who are immunocompromised received their third dose?
Pierre: No. Which is why—even though our phone lines are blowing up with calls from people interested in getting a booster shot—at this time we are prioritizing getting third doses to people who are immunocompromised, to give good practical and protective immunity to people who weren’t able to fully benefit from those first two shots alone. The booster shots are not authorized to begin until September 20.
The Brink: When you look at where this pandemic is going—with the Delta variant, we’re hearing a lot more about breakthrough cases, indicating not that the vaccines aren’t effective, but that instead Delta is highly contagious—do you think tweaks to vaccine formulations will be needed to protect against extremely infectious variants like Delta?
Pierre: The wonderful thing about mRNA vaccines in general is how quickly they can be deployed. We know Moderna, for example, is already looking at new coronavirus proteins to see if they can develop enhanced vaccines that further protect against variants. I hope this will continue, and we’ll see building out of the vaccine options. It’s also important to remember that all the data we’re seeing are happening amongst the backdrop of a world that isn’t fully vaccinated. As much as I want to shore up immunity with boosters, I recognize that no booster can protect us from evolving variants if we cannot distribute vaccines around the world, which allows the virus to keep spreading and evolving. I hope we do much better in the rollout and deployment of vaccines worldwide.
The Brink: Anything else you want people to know about booster shots?
Pierre: One other thing important to talk about is that a few months ago people were talking about getting their COVID antibodies tested. I would just say, we don’t have great information yet about how well commercial tests can tell us about protection based on the level of antibodies. So maybe save your time (and your money), because antibodies are only part of the immunity story. COVID infection or vaccination also provides T-cell activation, which can provide really good protection against severe infection and death, and an antibody test won’t tell you about that.
Also, I think people would like to know that here at Boston Medical Center, the vast majority of people who are hospitalized with COVID infections are unvaccinated. And the breakthrough cases we see are by and large in the extremely elderly or people who are severely immunocompromised and were not able to achieve adequate protection from their first vaccine doses.
The Brink: Why are booster shots necessary if the vaccines are working as well as scientists hoped?
Pierre: I really want to drive home the point that might be missed in the conversation about boosters: these vaccines have not failed us yet, to our knowledge. Breakthrough infections are expected, no vaccine is 100 percent effective. What we know is, here in the state of Massachusetts, 0.002 percent of fully vaccinated individuals have experienced severe disease. And so that’s a really small number of people. We just want to make sure that in the talk about boosters, if people are saying, well why should I bother if fully vaccinated people already need a booster? But I want to be clear that waning immunity is not the same as saying these vaccines have failed, because in fact, we want to give vaccines to prevent severe disease and death, and that’s what they’re doing. They’re working. This is what you want to see.
GOOD INFO. I’m wondering how soon after after receiving the booster does peak immunity occur? Is it several weeks, as with the first shots, or does it happen more quickly?
How long after getting the booster shot will it take effect?
How long after getting the booster shot will it take effect?
How long after my booster will it take effect?
What happened if pfizer booter done after 4 months if sinovac ?
How long does it take for the booster to become effective?
I want to know please how many weeks I have to wait , whether it is 2 or 3 weeks, before my 3rd booster shot fully takes effect. I am having it this coming Sunday, September 26th.
I’m 61 and had the 2nd shot in April, how long do I have to wait befoe getting the booster?
My husband and I just had the booster shot yesterday and we had the second dose in April if my memory serves me right. (I am 48 years old.)
I had my booster shot yesterday, & my second dose of sinovac 12 September 2021? 1 am 37 years old
How long before booster take effect ?
How long after getting the Moderna booster shot does peak immunity occur?
I have had covid and two doses of Pfizer. Is it ok to receive a moderna dose for a booster third shot?
I had two Moderna shots 6 months ago just got positive report for covid when do I go for the booster how long do I wait.
There is no place that says if you had covid last July and then six months later got two doses of the Moderna vaccine do you need a third shot or booster.
I had breakthrough covid. After my 2 vaccines. I cant find info anywhere info on if a booster is needed or not in this situation.
Thank you for this service. And info.
I have been searching for the same info, and if we can take a booster, how long after infection? First vaccines in February and infected in August.
I had two shots in March and got Covidi n August. I am 80 years old. Can I get a third shot?
What happens if get booster shot and test positive for Covid the same day
If you get a second booster shot how long will it take to become effective
What happens if you get your second booster shot the day after being exposed to the virus
I was positive for covid 9 days ago and my job is giving the booster shots tomorrow witch will be my tenth day of having COVID so can I still get the booster shot
This is the best and most informative information I have read for days about the booster and the vaccine! Thank you – after reading this I feel a bit more encouraged that those of us who are vaccinated will be doing well in the hard months ahead. Thank you to science and medicine !!
Car molested vaccination in January as a health care worker. Just finished with Covid. Do I also need a booster.
My wife finished vaccination in may. Got covid more likely from me. Worse symptoms too. Does she need a booster
In order to get an effective immune response people who are immunocompromised need to get 3 doses as part of their primary vaccination series.
After 6 months do they still need a fourth dose as a booster?
I received my Pfizer booster and I’m anxious to hear about the Pfizer study as to what is the expected level of immunity percentages after the booster for infection/severe complications/death/break through infections, etc.. Can someone suggest where I might best find this info?
I am also hoping to see a response to Paul’s question above as to when the expected peak immunity is reached after the booster.
I have the same question, but can’t seem to find any answers to it.
Great article. What is the thinking about immunity in persons who had Covid or Covid plus vaccine?
The Moderna second shot made me sick as a dog for several days. Will the third shot do the same?
Just a sample of one, but I had a very strong reaction to the second dose. I was out flat the first day and it wasn’t until day 4 that I could function normally again.
I had a 3rd dose a couple of days ago (6 months after dose #2). The evening of the shot my arm hurt, like it might from a flu shot. The next day I felt a little icky, as if I had had too much to drink the night before and then slept too little. I went about my day but as an afterthought checked my temp that evening – 99.8. Today I feel pretty much normal. So, bottom line, I did experience a reaction but nowhere near what I did the first time around.
Apparently I’m officially considered immunocompromised because of strong chemo I received a few years ago but I don’t think my system reacts differently from the norm, I think I was just in the unlucky 1% that gets really, really sick from the vaccine. Still better than Covid!
I also had a bad reaction to the Pzifer 2nd shot. I had the Virus in December and got the shots in May. I’m petrified to get the Booster. I was so sick for 6 days and one step from going to the emergency room.
On the 5th or 6th night I broke out in hives all over my body and they were horrendous, but within the next day I started to recover. Should I get the booster or could it make more even more sick or kill me. Hives are dangerous so they could kill me.
Same with me I had chemo in 2016 I had very bad reaction to my second moderna vaccine was admitted to the ER twice afterwards. I’m debating on my booster vaccine.
I got the booster 8/23. I’m immunocompromised. The 2nd dose, I was slightly tired and swollen at injection site and then I got a lump under my arm that hurt, but subsided after taking Ibuprofen. For the additional dose, I felt very icky. I was tired, but couldn’t sleep and never got a fever (I’m usually @ 97.0 and I got up to 98.1. I was feeling slightly nauseous. So, technically, it was a little worse than first time around (different), but still mild.
I got terribly sick the night of my 2nd dosage and all next day. I had a fever of 101.5 and had to take Tylenol to get it down. When I got my 3rd shot, my booster, I had no problems at all, not even a sore arm. I was also told this would be the case by the nurse who administered my shot. She said that most people weren’t having reactions, or if so, very bad reactions.
If you had Covid and you are vaccinated, how long should you wait to get the 3rd (booster) injection?
I have the exact same question. I did not see a response to your question as to when can you get a booster if after being vaccinated you got the Delta Covid. Thank you.
I was vaccinated in March tested positive for Covid mid-September I am 71 years old did not have a bad case but I am also wondering if and when I can get the booster??
I have the same question. Vaccinated with Pfizer, second dose in Feb 2021. Breakthrough Covid about 30 days ago. When can I get booster. When can I get flu vaccine?
Additional info: I am 72 years old with type 2 diabetes, HTN, and hyper cholesterol Emma.
I received the Moderna first in December 2020 and the second vaccine Moderna in January 2021 I am a healthcare worker and just received my booster ….however when I return to the same hospital to get the booster it wasn’t until she was getting ready to give me the vaccine that she said and showed me OK here is the Pfizer 0.3 …. I told her that I got to previous Moderma and was it OK to mix with the booster ….they gave me a Pfizer booster… I know that the CDC has not recommended that but I was told by the hospital that they’re both MNRA and that it would be fine…Can you tell me if this is OK since on my vaccine card I now have two Moderna and one Pfizer booster …. And going forward in the years to come should I just continue to get Moderna? Thank you
I have read, at least twice (not positive, but think one was on CDC site) that mixing Pfizer and Moderna can actually increase the level of protection. It’s the same science– I can’t imagine that one would be harmed by another brand.
will the booster dose be the same volume as the initial immunization ( .3ml Pfizer and .5 ml Moderna)?
THIS IS A GREAT ARTICLE. IS THERE ANY DATA THAT SHOWS THERE IS AN ADVANTAGE TO GETTING THE OPPOSITE mRNA FROM YOUR ORIGINAL SERIES TO PROVIDE BROADER MECHANISMS OF IMMUNITY? I HAVE READ THAT “Too many doses of the same vaccine may mean that you are less protected when getting vaccinated against the mutants long term. This is called “original antigenic sin.” ARE THERE ANY MODIFIED mRNA VACCINES TO ADDRESS OTHER VARIANTS THAT ARE WORTH WAITING FOR? ALSO, WHAT MARKERS CORRELATE MOST WITH PROTECTION? AS A HEALTHCARE PROVIDER, I COMPLETED MY PFIZER SERIES ON FEB 8TH. I RECENTLY HAD IgG ANTIBODY TESTING WHICH INDICATED THAT I HAD NO ACTIVE ANTIBODIES. WHAT DOES THIS MEAN REGARDING MY PROTECTION AGAINST INFECTION? IS THERE ANY BETTER TEST TO SUGGEST YOUR LEVEL OF PROTECTION? SO I ASSUME I DEFINITELY NEED A BOOSTER BUT WHICH SHOULD I GET OR SHOULD I WAIT FOR A NEW VARIANT mRNA TO COME OUT? THANKS!!
Can you provide links to studies
I was wondering the same thing about mixing the Pfizer and Moderna. I got the Pfizer originally and today got the Pfizer booster, but was very interested in mixing them. I chickened out. I wasn’t aware of the “original antigenic sin” concept. That is interesting and makes sense.
I got an antibody test yesterday (finger prick blood draw) at CVS to see what it said. I had gotten one before I was vaccinated and had no antibodies then. The test was 38.00 out of pocket. It told me that I definitely had no antibodies from the past three months IGM section and there was the slightest faint red line in the IGG section which could barely be seen that means I had antibodies at one point. My second vaccine date for Pfizer was 3/6/21, almost 7 months ago. With that data, I decided to get another antibody test this morning from Lab Corp for 10.00 out of pocket (insurance covers the rest). I made the appointment online. This test is a different type and will tell me a percentage or number range specifically. I’m very curious to what it says. I will be doing another one from Lab Corp in about 6 weeks to see if there is a big change. I also want my family members who got Moderna to get the labcorp test as an experiment as I have a hunch that they will show more antibodies based on the findings that the Pfizer vaccine is now only 39% effective and the Moderna is 76%. I drove four hours out of my way to get the Pfizer because of the 3% difference, but I regret that now. One thing that I learned from reading this article was that the T cell reaction is another very important measure and to not go by antibody levels alone. I just decided to do a personal study individually since I know that none of us have had Covid. I get tested weekly and the others are hermits.
Does the booster (3ed) still take 14 days to be fully effective?
Please answer I tested no antibodies for COVID found . I got Booster today how long am I protected and fully
That is my question as well- nothing online about this.
If you have an autoimmune disease are you more likely to get the Delta virus than someone with a good immune system? Will persons with an autoimmune disease be
listed as a greater risk and be vaccinated sooner than those without?
Thanks for the informative article.
As noted, immunocompromised people, such as me, who were vaccinated with the J&J vaccine are left completely in the lurch. We cannot get a booster shot of any of the vaccines. In my case, I was on immunosuppression when I got the J&J vaccine. Three months later I got a blood test to see if I had any COVID antibodies — and I had none. Effectively I’m unvaccinated. My rheumatologist suggests I start all over by getting a series of one of the mRNA vaccines because I am off immunosuppression for now. But, no one is willing to vaccine me with one of the mRNA vaccines, leaving me wide open to COVID infection. I consider this a serious system failure of the FDA and CDC. It certainly is not patient centered. Suggestions appreciated!
(BTW, recent evidence, not conclusive, is that Moderna will be better for immunocompromised individuals than Pfizer.)
If I am a heart patient and had my second Moderna vaccine on 3/25/2021 when can I get my booster
If you are considered immunocompromised, you can get them now. Consult your doctor. It’s not considered a booster for immunocompromised, it’s just an additional dosage. If you are not considered immunocompromised, then you’ll have to wait until it’s your time for the booster shot (8 months after 2nd dose of the initial series).
I can’t seem to find any info about how soon the Booster actually “boosts” a vaccinated person’s immunity back to where it needs to be after 8 months. Will we need to wait weeks like we did with the 2 shots?
How long do you need to wait to get third shot after the initial vaccines. Wife is on steroids for Polymylgia and would like to get third shot. Thank You.
You didn’t mention natural immunity
If I receive the Covid19 Vaccine Booster. When will it take its full effect?
I had my booster shot yesterday, & my second dose of sinovac 12 September 2021? 1 am 37 years old
Gap between pfizer & sinovac is 4 months, is there any problem? Please guide
I had my 3rd shot of Moderna Sept 6, 2021 and tested positive for covid Sept 14th. Had been to Dr on 13th for allergy symptoms. Was given steroid shot and Claritin. Next day realized food had no taste and went for test. Doing fine and never really felt bad. Guess 3 shots helped. I am 82 female
Is there any danger in getting a booster shot if you are asymtomatic
My (Canadian) husband received AstraZeneca as his 1st shot. After the appropriate time internal, he received Moderna as his 2nd shot. In the eyes of the CDC he is not fully vaccinated. Will a Moderna booster render him fully vaccinated? Surely he won’t be considered unvaccinated forever….? How does one rectify a “mixed vaccine” scenario to enable international travel to those countries who don’t recognize it?
I just received my third covid-19 booster shot and was wondering how long the antibodies stay strong after the third booster
I received a phizer vaccination. the first shot I had adverse effects and chose not to take the second shot will I qualify for a booster ? it has been over one year since I was vaccinated. What should I do?
I am 70 years old, with high blood pressure and overweight. Ive had two doses of Moderna, the last on 2-1-2021. Am i considered immune compromised, and should i get the Phizer booster or wait for the Moderna when it becomes available. Thanks for the great article.
‘will getting the Pfizer booster in anyway affect COVID test results used for travel?
If you had the 2 modernas and 6 months later got the delta, do you need a booster?
I had my 2 shots and had Covid last month do I have to wait until I get me booster shot?
Without reading every single piece of information, are the covid Pfizer booster shots activating your immune immediately thus bringing it back to 95%+
I have 2 Pfizer jabs over 6 months ago
Presently in Thailand
I’m finding it hard to get Pfizer booster jab
Can I safely use a different vaccine??
Are there any reasons that would prevent me from receiving the Booster?
E.g. if i received a Flu shot and Cortisone injections a week before my scheduled Booster?
Need the answer to this question ..ASAP!!!
What’s the Point of asking questions if no one will respond with an Answer! Many of these questions are Valid and many are duplicates…but no Answer! What’s up with that??????
Exactly what I was thinking!
2021-03-24 Pfizer-BioNTech [ Tozinameran 0.3 mL ] – mild ache for two days at injection site
2021-04-14 Pfizer-BioNTech [ Tozinameran 0.3 mL ] – mild chill awaken in early morning after
2021-09-28 Moderna [ mRNA-1273 0.25 mL ] – no symptom yet since jab at 0056 GMT
Moderna vaccine booster dosage reduced due to government expert health committee that reviewed the dosing for the Moderna vaccine used for boosting and recommended that 50mcg of the Moderna vaccine be used for boosting given evidence that a 50mcg dosage is sufficient to boost immune response significantly.
by male age 60 ectomorph 48 to 50 kg 1.68m
if received the 3rd booster do I need get tested weekly or monthly
I’m so glad I was able to find someone else asking the question. I got vaccinated at end of January. I got a breakthrough case of Covid end of July, which was 6 months after receiving vaccine. I’m a health care worker and want to know if I should get the booster and if so when. I didn’t see the response of the other person asking same question.
If you had the initial 2 doses of vaccine and still got covid, how long do you need to wait after having covid-19 before getting the booster?
I received the Pfizer booster on Monday. I did not have any reactions to the fist two. I am so sick! Fever, body aches, chills, sweating profusely and diarrhea, I couldn’t go to work again today. When will I feel better?
I am wondering the same very sick after Pfizer booster
I’ve had both doses of Pfizer. I recently had Covid. Do I need to wait a specific amount of time to have the booster?
I am am fully vaccinated, for six months today, however. I got a breakthrough COVID infection. How long after I have had COVID can I get a booster?
How long does it take for the booster shot (to clarify, the third shot for people who have underlying health conditions) to become fully effective?
How long after getting booster of Moderna will I get full immunity? I have chronic fatigue and heart disease and feel tired most of the time. Will this booster shot make me more confident in not getting Covid. Do you think it would be ok to substitute teach young kids in the schools? Thanx, I’m tired of staying home, but don’t want to take a big chance on Covid?
I am needing to know how long I need to wait after having covid and receiving the monoclonal treatment before I can get the 3rd shot or booster? I do have type 1 dm and also work in a medical facility.
I have the same question. I had a breakthrough infection about 30 days ago. I am 72 with type 2 DM, HTN, and hypercholesterolemia. Pfizer vaccinated, last dose Feb 2021. When can I get a booster?
I am not a conspiracy theory person. However…
1. I had heard that the COVID Vaccine Booster destroys the Immune system (wbc production) over time, especially in older patients (> 60’s) with immune compromised and co-morbid disorders. I do not know if this with one or all of the COVID Boosters.
2. I have heard that most of the high-level people in the Government / Politian’s have not gotten the COVID Vaccines nor the Boosters.
I am very concerned about what is true vs. fiction. Some Vaccines have DNA, or RNA and Protein Spikes have been added. Also Scientist do not know the “long term effects” of the Protein Spikes or Vaccines.
If I take the booster shot, what effect will I have towards an unvaccinated person?
I had my Moderna Booster shot Feb 18,,,,,,,SO Oct 18 it will be 8 months. Now what? Are you going to need a shot every year? Or would it be good to get a test for antibodies?
False promises, poi.., deceptions and seductions of a fearsome mixture , ..son.
My Mum is having her 3rd jab this week. We are going on a cruise next week, would the test we do before boarding show she has Covid because of the third jab only being a week ago please?
seems that Moderna vaccine dosage of 0.5 mL, 0.5 mL and booster dosage of 0.5 mL resulted in higher antibodies level. according to NIH study stated in article at URL yet to peer review
however, each individual human being is unique to self that is – different person = different body
I had a strong reaction and had to go to hospital with my first Pfizer shots, should I still get the booster?
I’m a Type 1 diabetic and since receiving my Pfizer booster I’ve had blood glucose readings reach 400 and above requiring at least twice the amount of insulin injections than normal. As of this writing it’s been 3 weeks since my booster injection and my glucose readings are not back to normal. Prior to my booster shot I didn’t read or hear anything regarding this type of reaction. I strongly suggest that diabetics contact their endocrinologists regarding this issue.
I’m a 30 year old female that is slightly over weight. I got my second dose of Pfizer in February and work in the administration side of healthcare (no patients, but in hospital). Do I need the booster or are my levels from my first set still sufficient?
“Everything you need to know about the Covid Booster” but evidently no one needs to know or wants to know how long it takes for the third shot to become effective—if ever. I would think that would be one of the most important things to know. But you won’t find the answer anywhere on the web. Odd that.
How long does it take for the 3rd shot to become effective? Hello Boston University, are you there?
How about NOT calling your article ‘everything you need to know’ when it’s not everything I need to know? My question, which is REALLY obvious and REALLY important, is how long does it take after the booster shot for maximum immunity to occur. Seriously, guys, you REALLY didn’t think that was important?
PLEASE answer the question by John Perry and others regarding how long it takes to realize maximum benefit from a booster shot!
I received Moderna jabs #1 and #2, both of which gave me a headache and caused fatigue. I received my Moderna booster about ten days ago. Given what I read, I was expecting the next day to be similar to my first and second experiences. However, no symptoms of any type. Is that normal? I wondered if the dose was too low or if it exited my arm when the needle was withdrawn.
I have just recieved my pfizer booster (0.3 ml) the dr said that I will need another booster in 28 days. I have never heard of a booster booster. Is this correct? I had my 2nd Astra Zeneca six months ago. I live in Kenya
I had the booster and had side effects for almost 14 days. First 5 days I had a fever. body aches and
slept around the clock. Then I was tired and slept most of the time. Is this unusual. The first 2 shots
I had no side effects at all,
1st shot 3-19-21
2nd shot 4-25-21
3rd shot 11-16-21
Have a friend that got a full dose of Madera booster, what should he be aware of. He is in terrible pain, legs are swollen…
1) How fast do the T Cells and the B Cells decline.
2) Isn’t that the most important question since anti bodies are SUPPOSED to wane as the other 2 immune defense mechanisms build up?