This course teaches the fundamentals of molecular parasitology based on recent advances in understanding cellular structures, gene expression mechanisms and signaling pathways in apicomplexan and kinetoplastid unicellular parasites, and model nematodes. It focuses on research applications targeting parasite-specific cellular processes and parasite- host interactions as potential points of therapeutic intervention. Current state-of-the-art genetics, genomics, proteomics and structural approaches used in parasite research will be emphasized. Class meetings include a didactic lecture followed by discussion of the original research paper related to the lecture's topic. The research paper is presented in-depth by assigned group of 2-3 students with instructor acting as moderator. All students are required to read the selected papers before each class meeting and participate in discussion. Lectures are given by experts in respective topics. Course Director will participate in all class meetings to ensure quality of instruction, cohesiveness of topics and to handle student concerns. The course is expected to draw students from Master Programs in Biomedical Research Technologies and Medical Sciences, and PhD Program in Biomedical Sciences. It is expected that all students will have a solid foundation in molecular biology, biochemistry, genetics and microbiology, but not specific prerequisites are set forth. 2 cred. Fall semester.

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