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Portfolio - Life Sciences

As a diversified fund, we invest in both technology and life sciences opportunities. In the life sciences, we are active in these areas.

  • Medical devices and instruments
  • Drug discovery
  • Biotechnology including genomics and proteomics
  • Pharmaceuticals and drug delivery

OTD currently holds positions in the following representative companies:

Adipogenix
(BU company)

Developing pharmaceuticals that treat obesity based on technology developed by Dr. Barbara Corkey at BU. 

Adipogenix

Afferent
(BU Company):

Medical device company focused on treating neurologic dysfunction. The technology is based on the work of Dr. Jim Collins at BU.

Afferent

Cellicon Biotechnologies
(BU Company):

Developing novel anti-infective drug targets and compounds using its unique Systems Biology platform developed by Dr. Jim Collins at BU.

Cellicon
Elixir, Inc.
Drug discovery based on the genetics and signal transduction underlying age-related illnesses
Elixir, Inc.

Infinity Pharmaceuticals
Laboratory synthesis of new chemical entities with unprecedented structural diversity

Infinity
MicroCHIPS, Inc.
Implantable, microchip-based drug delivery and biosensory systems
MicroCHIPS, Inc.

Modular Genetics
(BU Company)

The company's technology, CombiGenix TM, is a universal system used for designing and creating large sets of engineered genes.

Modular Genetics

Ophthonix
Developer of iZonTM high resolution lenses.

SelectX Pharmaceuticals
New chemical entities produced by cloned biosynthetic pathways

Select X

Previous Investments:

Acusphere, Inc.
Contrast agents for ultrasound imaging applications.
IPO:
2003 (NASDAQ: ACUS)

Acusphere, Inc.
AtheroGenics, Inc.
Therapeutic treatment of atherosclerosis and other diseases.
IPO: 2000 (NASDAQ: AGIX)
AtheroGenics, Inc.
Cynosure, Inc.
Medical devices for cosmetic laser surgery. Acquired by Italian company El. En. S. p. A. in May 2002.
Cynosure, Inc.
Exact Sciences, Inc.
Non-invasive diagnostic for early detection of colorectal cancer.
IPO: 2001 (NASDAQ: EXAS)
Insmed Pharmaceuticals, Inc.
Therapeutic treatment of diabetes and metabolic disorders..
IPO: 2000 (NASDAQ: INSM)
Insmed Pharmaceuticals, Inc.
Ligand, Inc.
Fusion proteins for treatment of cancer, psoriasis, and other diseases.
Seragen IPO: 1992 (NASDAQ:SRGN)
Acquired by: Ligand Pharmaceuticals Inc. 1998 (NASDAQ:LGND)
Ligand, Inc.
Myriad Genetics, Inc.
Genomics-based drug delivery and diagnostics.
IPO: 1995 (NASDAQ: MYGN)
Myriad Genetics, Inc.
NitroMed, Inc.
Nitric oxide enhanced medicines IPO: 2003 (NASDAQ: NTMD)
NitroMed, Inc.
Peer Review Analysis, Inc.
Health-benefits management services.
IPO: 1991 (NASDAQ:PRAI)
Acquired by: Core, Inc 1995 (NASDAQ:CORE)
Core, Inc.
Sequenom, Inc.
DNA analysis tools and systems..
IPO: 2000 (NASDAQ:SQNM)
Sequenom, Inc.
Summit Technology, Inc.
Ophthalmic laser systems.
IPO: 1998 (NASDAQ: BEAM)
Summit Technology, Inc.
Vista Medical Technologies, Inc.
Visualization systems for minimally invasive surgery.
IPO: 1997 (NASDAQ: VMTI)
Vista Medical Technologies, Inc.
Visualization Technology, Inc.
Image-guided surgery systems. Acquired by General Electric (NYSE: GE) in April 2002.
Visualization Technology, Inc.

Venture Capital Investments
 
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Technology Department | April 3, 2007 | Contact
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