Biosafety Bulletin Vol 3 Issue 1 – April 2016

A quarterly newsletter from the BU Office of Institutional Biosafety Committee See the PDF of the April 2016 Biosafety Bulletin NIH Site Visit On February 24, 2016, NIH Office of Science Policy visited Boston University as a part of their decade long program to engage with and to evaluate performance of the IBCs around the […]

Appendix I: Summary of Requirements for Biosafety Levels

Safety Guideline BSL1 BSL2 BSL3 BSL4 Laboratory personnel must wash their hands after handling cultures, removing gloves, and before leaving the laboratory. Y Y Y Y Eating, drinking, and application of cosmetics is prohibited. Y Y Y Y Personnel must be familiar with basic biosafety procedures, including this manual. Y Y Y Y Personnel should […]

Appendix H: Prion Research/Creutzfeldt-Jacob Disease (CJD) Guidelines

Creutzfeldt-Jacob Disease (CJD) is one of a group of neurodegenerative diseases called transmissible spongiform encephalopathies (TSE) (or prion diseases) which affect humans (e.g., Kuru, Fatal Familial Insomnia and Gerstmann-Sträussler-Scheinker syndrome of humans) and a variety of domestic and wild animal species (e.g., Scrapie of sheep, “Bovine Spongiform Encephalopathy [BSE] or Mad Cow Disease” of cattle […]

Appendix E: Biosafety Level 3 (BSL3) and Biosafety Level 4 (BSL4) Requirements and Practices

Biosafety Level 3 and 4 (BSL3/4) is the recommended containment for work with agents or toxins that may cause serious or potentially fatal disease through inhalation exposure. Work at BSL3/4 requires enhanced facility design, operational controls and special practices, which are outlined in the BSL3 Biosafety Manual and BSL4 Biosafety Manual. BSL3/4 facilities are designed […]

Facility Access

Requirements for Access In order to conduct research involving animals, researchers must first obtain security access to the specific facility they will need to use. Prior to obtaining access, please complete the following steps: Review ROHP requirements for medical clearance and take steps to obtain medical clearance from ROHP Complete the following online trainings in […]

Appendix J: Summary of Requirements for Animal Biosafety Levels

Safety Guideline ABSL1 ABSL2 ABSL3 ABSL4 Access is limited or restricted at the discretion of the laboratory for satellite laboratories or the Attending Veterinarian for all laboratories. Y Y Y Y Personnel must wash their hands after handling cultures and animals, removing gloves, and before leaving the facility. Y Y Y Y Eating, drinking, and […]

Appendix K: Bloodborne Pathogen Standard

Avoiding occupational exposure to human blood, body fluids, and tissues is the primary way to prevent transmission of bloodborne pathogens. The goal of the initial and annual standard precautions training is to present information on how to prevent such exposures by administrative controls, workplace engineering controls, proper work practices, personal protective equipment, and a hepatitis […]

Appendix L: Working Safely with Animals

Working with animals poses potential additional health and safety hazards that require extra precautions. The specific requirements will depend on the types of activities (e.g., surgery, feeding animals, use of anesthetic agents, etc.) and the specific species used. Personnel Guidelines Personnel should follow the following guidelines: Follow the specific requirements established in the IACUC-approved protocol […]

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