The National Institutes of Health (NIH)


Research (R, P, D and U Announcements)

Title (Activity Code) Deadline Announcement Number
Metastasis Research Network (U54 Specialized Center-Cooperative Agreement) May 28, 2021 RFA-CA-20-029
Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Exploratory/Developmental Grants Phase II) May 27, 2021; September 29, 2021 RFA-CA-21-004
NIDCR Award for Sustaining Outstanding Achievement in Research (SOAR) (R35 Outstanding Investigator Award) July 8, 2021 RFA-DE-22-001
Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Exploratory/Developmental Grants Phase II) May 27, 2021; September 29, 2021 RFA-CA-21-006
Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R21 Exploratory/Developmental Research Grant) May 27, 2021; September 29, 2021 RFA-CA-21-003
Innovative Biospecimen Science Technologies for Basic and Clinical Cancer Research (R21 Exploratory/Developmental Research Grant) May 27, 2021; September 29, 2021 RFA-CA-21-005
Development of Innovative Informatics Methods and Algorithms for Cancer Research and Management (R21 Exploratory/Developmental Research Grant) June 8, 2021; November 17, 2021 RFA-CA-21-013
National Dental Practice-Based Research Network Clinical Trial or Observational Study Planning and Implementation Cooperative Agreement (UG3/UH3 Exploratory/Developmental Phased Award Cooperative Agreement) June 9, 2021, and October 8 2021; February 9, 2022, June 9, 2022, and October 7 2022; February 9 2023, June 9, 2023 PAR-20-306
Health Services Research on Minority Health and Health Disparities (R01 Research Project Grant) November 17, 2021; March 17, 2022; November 17 2022; February 17, 2023 PAR-20-310
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Research Project Grant) May 26, 2021; September 28, 2021; January 26, 2022; May 26, 2022; September 27, 2022; January 26, 2023; May 26, 2023; September 26, 2023 PAR-21-038
Enabling Technologies to Accelerate Development of Oral Biodevices (R41/R42 Small Business Technology Transfer (STTR) Grant – Phase I, Phase II, and Fast-Track) September 5, January 5, April 5 PA-19-075
Disseminating and Implementing Patient-Centered Outcomes Research (PCOR) Evidence into Practice through Interoperable Clinical Decision Support (R18 Research Demonstration and Disseminations Projects) January 25, May 25, September 25 PA-20-074
Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R01 Research Project Grant) February 5, June 5, October 5 PAR-20-276
Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R21 Exploratory/Developmental Research Grant) February 16, June 16, October 16 PAR-20-277
Biologic Factors Underlying Dental, Oral, and Craniofacial Health Disparities (R21 Exploratory/Developmental Research Grant) February 16, June 16, October 16 PA-18-874
Biologic Factors Underlying Dental, Oral, and Craniofacial Health Disparities (R01 Research Project Grant) February 5, June 5, October 5 PAR-18-875
Improving oral health and reducing disparities in adolescents (R01 Research Project Grant) February 5, June 5, October 5 PAR-20-058
NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Small Grant Program) February 16, June 16, October 16 PAR-20-046
: Improving oral health and reducing disparities in adolescents (R21 Exploratory/Developmental Research Grant) February 16, June 16, October 16 PAR-20-059
: NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Research Project – Cooperative Agreements) February 5, June 5, October 5 PAR-20-060
: Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) Beginning June 5, 2021 NOT-DE-21-001
NIH Research Project Grant (R01 Research Grant) February 5, June 5, October 5 PA-20-185
NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Small Grant Program) February 16, June 16, October 16 PA-20-046
NIH Exploratory/Developmental Research Grant Program (R21 Research Grant) February 16, June 16, October 16 PA-20-195
NIH Support for Conferences and Scientific Meetings (R13) April 12, August 12, December 12 PA-21-151
Using Innovative Digital Healthcare Solutions to Improve Quality at the Point of Care (R21/R33 Phased Innovation Award) February 16, June 16, October 16 PA-21-164
NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award) February 12, June 12, October 12 PAR-21-060
Notice of Special Interest: Administrative Supplements to Support Dentist Scientists Post Specialty or Residency to Develop Expertise in Dental, Oral and Craniofacial Research Varies NOT-DE-20-035
Notice of Special Interest (NOSI): Simulation Modeling and Systems Science to Address Health Disparities Varies NOT-MD-20-025
Innovative Research in Cancer Nanotechnology (IRCN) (R01 Research Project Grant) Varies PAR-20-284
Notice of Special Interest (NOSI): Development and Preliminary Testing of Health-related Behavioral Interventions Varies NOT-OD-20-106
Notice of Special Interest (NOSI) of NIDCR in Supporting Dental, Oral, and Craniofacial Research Using Bioinformatic, Computational, and Data Science Approaches Varies NOT-DE-20-006
Enabling Technologies to Accelerate Development of Oral Biodevices (R21 Research Grant) February 16, June 16, October 16 PAR-20-232
Enabling Technologies to Accelerate Development of Oral Biodevices (R01 Research Grant) February 5, June 5, October 5 PAR-20-233
Notice of Special Interest: Health Services Research on Minority Health and Health Disparities (R01 Research Project Grant) February 5, June 5, October 5 NOT-MD-20-011
Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Research Project Grant) February 5, June 5, October 5 PAR-20-155
Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Research Project Grant) February 5, June 5, October 5 PAR-20-131
National Dental Practice-Based Research Network Infrastructure Access (X01 Resource Access Award) September 1 PAR-20-073
Biomedical Data Repository (U24 Resource-Related Research Projects – Cooperative Agreements) January 25, September 25 PAR-20-089
National Cancer Institute Program Project Applications (P01 Research Program Projects) January 25, May 25, September 25 PAR-20-077
Improving oral health and reducing disparities in adolescents (R01) February 5, June 5, October 5 PAR-20-058
Improving oral health and reducing disparities in adolescents (R21) February 16, June 16, October 16 PAR-20-059
NIDCR Small Grant Program for New Investigators (R03) February 16, June 16, October 16 PAR-19-370
Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional) September 25 PAR-19-259
Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42) January 5, April 5, September 5 PA-19-021
Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R43/R44) January 5, April 5, September 5 PA-19-022
Enabling Technologies to Accelerate Development of Oral Biodevices (R41/R42) January 5, April 5, September 5 PA-19-075
Enabling Technologies to Accelerate Development of Oral Biodevices (R43/R44) January 5, April 5, September 5 PA-19-076
NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03) February 16, June 16, October 16 PAR-19-145
Mechanistic Studies of Gene-Environment Interplay in Dental, Oral, Craniofacial, and Other Diseases and Conditions (R01) February 5, June 5, October 5 PAR-19-292
Development of Novel and Robust Systems for Mechanistic Studies of Gene-Environment Interplay in Dental, Oral, Craniofacial, and Other Diseases and Conditions (R21) February 16, June 16, October 16 PAR-19-293
Precision Imaging of Oral Lesions (R01/R21) R01: February 5, June 5, October 5 / R21: February 16, June 16, October 16 PAR-18-787 (R01)/PAR-18-788 (R21)
Biologic Factors Underlying Dental, Oral, and Craniofacial Health Disparities (R01/R21) R01: February 5, June 5, October 5 / R21: February 16, June 16, October 16 PA-18-874
Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01) R01: February 5, June 5, October 5 PA-18-876
Clinical Research to Improve the Oral Health of Older Adults (R21) October 16, February 16, June 16 PAR-19-240
Clinical Research to Improve the Oral Health of Older Adults (R01) October 5, February 5, June 5 PAR-19-239
NIDCR Small Grant Program for New Investigators (R03 Small Grant Program) February 16, June 16, October 16 PAR-21-084

Training (K Announcements)

Title (Activity Code) Deadline Announcement Number
Mentored Research Scientist Development Award (K01 Training Grant) February 12, June 12, October 12 PA-20-190
Mentored Quantitative Research Development Award (K25 Training Grant) March 12, July 12, November 12 PA-20-199
Mentored Clinical Scientist Research Career Development Award (K08) February 12, June 12, October 12 PA-19-117
Short-term Mentored Career Enhancement Award in Dental, Oral and Craniofacial Research for Mid-Career and Senior Investigators (K18 Career Enhancement Award) October 12, February 12, June 12 PAR-19-238
Midcareer Investigator Award in Patient-Oriented Research (K24) February 12, June 12, October 12 PA-19-122
Mentored Patient-Oriented Research Career Development Award (K23) February 12, June 12, October 12 PA-19-119
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00) February 12, June 12, October 12 PAR-19-144
NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 F99/K00 Individual Predoctoral to Postdoctoral Transition Award) February 12, June 12, October 12 PAR-20-069
NIDCR Small Grant Program for New Investigators (R03 Small Grant Program) February 16, June 16, October 16 PAR-21-084
NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award) February 12, June 12, October 12 PAR-21-060
NIDCR Dual Degree Dentist Scientist Predoctoral to Postdoctoral Transition Award (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award) February 12, June 12, October 12 PAR-21-108

Research (R, P, D and U Announcements)

Title: Metastasis Research Network (U54 Specialized Center-Cooperative Agreement)
Announcement Number: RFA-CA-20-029
Deadline: May 28, 2021
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to develop a comprehensive and cohesive understanding of cancer metastasis. Towards this goal, the National Cancer Institute (NCI) will support several U54 Specialized Centers that together will form the Metastasis Research Network (MetNet). Each MetNet Center should propose an overarching scientific theme that will be pursued through two or three scientific inter- and multi-disciplinary basic research projects. The projects should use integrative approaches to elucidate and integrate a mechanistic understanding of the non-linear, dynamic, and emergent processes in metastasis. Overarching themes should encompass the interplay between at least two central elements in the metastatic process such as early dissemination, cellular and/or physical microenvironment crosstalk, dormancy, or mechanisms of responses by metastatic cells to therapies.
Research proposed by MetNet Centers is expected to advance our understanding towards a more comprehensive appreciation of metastasis as a whole body, systems-level problem.
Award: Application budgets may not exceed $1.2M per year in direct costs.
Eligibility & Guidelines: Here
Announcement Expires:  May 29, 2021


Title: Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Exploratory/Developmental Grants Phase II)
Announcement Number: RFA-CA-21-004
Deadline: May 27, 2021; September 29, 2021
Purpose: This Funding Opportunity Announcement (FOA) invites grant applications proposing exploratory research projects focused on further development and validation of emerging technologies offering novel capabilities for targeting, probing, or assessing molecular and cellular features of cancer biology for basic or clinical cancer research. This FOA solicits R33 applications where major feasibility gaps for the technology or methodology have been overcome, as demonstrated with supportive preliminary data, but still requires further development and rigorous validation to encourage adoption by the research community. Well-suited applications must offer the potential to accelerate and/or enhance research in the areas of cancer biology, early detection and screening, clinical diagnosis, treatment, control, epidemiology, and/or address issues associated with cancer health disparities. Technologies proposed for development may be intended to have widespread applicability but must be focused on improving molecular and/or cellular characterizations of cancer. Projects proposing application of existing technologies where the novelty resides in the biological or clinical target/question being pursued are not responsive to this solicitation and will not be reviewed.
Award: Direct costs are limited to $300,000 per year. Application budgets need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: September 29, 2021


Title: NIDCR Award for Sustaining Outstanding Achievement in Research (SOAR) (R35 Outstanding Investigator Award)
Announcement Number: RFA-DE-22-001
Deadline: July 8, 2021
Purpose: The objective of the NIDCR Award for Sustaining Outstanding Achievement in Research (SOAR) is to provide longer-term support to NIDCR-funded investigators, who are in their mid-career stage, and have outstanding records of research productivity, mentorship and professional service to the research community. It is expected that the SOAR Award will propel the investigator along this career trajectory and allow him/her to embark on ambitious longer-term projects of extraordinary potential within the mission of NIDCR. This award supports research projects for up to eight years.
Award: Application budgets are limited to $650,000 direct costs per year for all years, and must reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: July 27, 2021


Title: Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Exploratory/Developmental Grants Phase II)
Announcement Number: RFA-CA-21-006
Deadline: May 27, 2021; September 29, 2021
Purpose: This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on further development and validation of emerging technologies that improve the quality of the samples used for cancer research or clinical care. This includes new capabilities to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. This FOA solicits R33 applications where major feasibility gaps for the technology or methodology have been overcome, as demonstrated with supportive preliminary data, but still require further development and rigorous validation to encourage adoption by the research community. The overall goal is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. This FOA will support the development of tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection and screening, clinical diagnosis, treatment, epidemiology, or address issues associated with cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality. Projects proposing to use existing technologies where the novelty resides in the application of the technology or the biological or clinical question being pursued, and not the technical capabilities being developed, are not appropriate for this FOA and will not be reviewed.
Award: Direct costs are limited to $300,000 per year. Application budgets need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: September 30, 2021


Title: Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R21 Exploratory/Developmental Research Grant)
Announcement Number: RFA-CA-21-003
Deadline: May 27, 2021; September 29, 2021
Purpose: This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on the early-stage development of highly innovative technologies offering novel molecular or cellular analysis capabilities for basic or clinical cancer research. The emphasis of this FOA is on supporting the development of novel capabilities involving a high degree of technical innovation for targeting, probing, or assessing molecular and cellular features of cancer biology. Well-suited applications must offer the potential to accelerate and/or enhance research in the areas of cancer biology, early detection and screening, clinical diagnosis, treatment, control, epidemiology, and/or address issues associated with cancer health disparities. Technologies proposed for development may be intended to have widespread applicability but must be focused on improving molecular and/or cellular characterizations of cancer biology. Projects proposing the application of existing technologies where the novelty resides in the biological or clinical target/question being pursued are not responsive to this solicitation and will not be reviewed.
Award: Direct costs are limited to $400,000 over a 3-year period, with no more than $200,000 in direct costs allowed in any single year.
Eligibility & Guidelines: Here
Announcement Expires: September 30, 2021


Title: Innovative Biospecimen Science Technologies for Basic and Clinical Cancer Research (R21 Exploratory/Developmental Research Grant)
Announcement Number: RFA-CA-21-005
Deadline: May 27, 2021; September 29, 2021
Purpose: This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on the early-stage development of highly innovative technologies that improve the quality of the samples used for cancer research or clinical care. This includes new capabilities to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. The overall goal is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. This FOA will support the development of tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection, and screening, clinical diagnosis, treatment, epidemiology, or address issues associated with cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality. Projects proposing application of existing technologies where the novelty resides in the biological or clinical target/question being pursued are not responsive to this solicitation and will not be reviewed.
Award: Direct costs are limited to $400,000 over a 3-year period, with no more than $200,000 in direct costs allowed in any single year. Application budgets need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: September 30, 2021


Title: Development of Innovative Informatics Methods and Algorithms for Cancer Research and Management (R21 Exploratory/Developmental Research Grant)
Announcement Number: RFA-CA-21-013
Deadline: June 8, 2021; November 17, 2021
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to invite exploratory/developmental research grant applications (R21) for the development of innovative methods and algorithms in biomedical computing, informatics, and data science addressing priority needs across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI’s Informatics Technology for Cancer Research (ITCR) Program, this FOA encourages applications focused on the development of novel computational, mathematical, and statistical algorithms and methods that can considerably improve acquisition, management, analysis, and dissemination of relevant data and/or knowledge. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, there must be a clear rationale for how the proposed informatics method or algorithm is novel and how it will benefit the cancer research field. Potential applicants who are interested in downstream technology development, from prototyping to hardening and adaptation, should consult the other companion FOAs listed above.
Award: Direct costs are limited to $275,000 over a two year period. No more than $200,000 may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: November 18, 2021


Title: National Dental Practice-Based Research Network Clinical Trial or Observational Study Planning and Implementation Cooperative Agreement (UG3/UH3 Exploratory/Developmental Phased Award Cooperative Agreement)
Announcement Number: PAR-20-306
Deadline: June 9, 2021, and October 8 2021; February 9, 2022, June 9, 2022, and October 7 2022; February 9 2023, June 9, 2023
Purpose: The National Institute of Dental and Craniofacial Research (NIDCR) is continuing support for research conducted within a dental Practice-Based Research Network (PBRN). The National Dental PBRN Administrative and Resource Center and National Coordinating Center support the infrastructure for and implementation of multiple observational studies and clinical trials. This Funding Opportunity Announcement (FOA) is soliciting applications for clinical trials and large clinical observational studies to be conducted in the National Dental PBRN through a milestone-driven UG3/UH3 cooperative agreement mechanism. Each UG3/UH3 award will support an individual project which will utilize the National Dental PBRN infrastructure and resources for study planning and implementation. This FOA supports a UG3 clinical study planning phase and potential transition to a UH3 implementation phase. Progression to the UH3 phase is based on an administrative review and is dependent on success in meeting UG3 milestones, consideration of the dental PBRN as an appropriate venue for conduct of the research, NIDCR program priorities, and availability of funds.
The main goals of the dental PBRN are to streamline the implementation of national oral health research studies in dental practices on topics of importance to practitioners and their patients, to provide evidence useful in daily patient care, and to facilitate the translation of research findings into clinical practice. This FOA encourages applications proposing research studies that align with the goals of the dental PBRN.
Award: The UG3 phase is limited to a total of $275,000 in direct costs over the entire UG3 phase. Application budgets for the UH3 phase are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: September 08, 2023


Title: Health Services Research on Minority Health and Health Disparities (R01 Research Project Grant)
Announcement Number: PAR-20-310
Deadline: November 17, 2021; March 17, 2022; November 17 2022; February 17, 2023
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to encourage innovative health services research that can directly and demonstrably contribute to the improvement of minority health and/or the reduction of health disparities at the health care system-level as well as within clinical settings.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires:  March 28, 2023


Title: Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Research Project Grant)
Announcement Number: PAR-21-038
Deadline: May 26, 2021; September 28, 2021; January 26, 2022; May 26, 2022; September 27, 2022; January 26, 2023; May 26, 2023; September 26, 2023
Purpose: The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Funding Opportunity Announcement (FOA) must not include preliminary data. Applications must include a separate attachment describing the change in research direction. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. This Funding Opportunity Announcement does not accept applications proposing clinical trials.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires:  December 29, 2023


Title: Enabling Technologies to Accelerate Development of Oral Biodevices (R41/R42 Small Business Technology Transfer (STTR) Grant – Phase I, Phase II, and Fast-Track)
Announcement Number: PA-19-075
Deadline: September 5, January 5, April 5
Purpose: This Funding Opportunity Announcement (FOA) invites applications that propose transformative engineering solutions to technical challenges associated with new development, substantial optimization of existing technologies and clinical translation of intraoral biodevices. Proposed technologies are expected to advance development of oral biodevices to clinical use, including but not limited to: precision medicine-based detection, diagnosis and treatment of oral and overall health conditions, and measurement of patient functional status and clinical outcome assessment. Areas of interest in this FOA include engineering approaches that allow integration of electronic, physical, and biological systems essential to the development of functional biodevices that are safe and effective for detection, diagnosis and treatment of oral and systemic disease. Products of this research will be proof-of-concept prototype biodevices, dedicated biosensors, associated core technologies and integrated approaches that enable development of safe and effective intra-oral biodevices intended for specific clinical applications. To streamline the development of oral biodevices that advance precision medicine-based approaches in clinical practice, this FOA encourages interdisciplinary collaborations across engineering, multifunctional sensors, pharmacology, chemistry, medicine, and dentistry, as well as between academia and industry.
Award: According to statutory guidelines, total funding support (direct costs, indirect costs, fees) normally may not exceed $150,000 for Phase I awards and $1,000,000 for Phase II awards. With appropriate justification from the applicant, Congress will allow awards to exceed these amounts by up to 50% as a hard cap ($225,000 for Phase I and $1,500,000 for Phase II). However, NIH has received a waiver from SBA, as authorized by statute, to exceed the hard cap of $225,000 for Phase I or $1,500,000 for Phase II for specific topics.
Eligibility & Guidelines: Here
Announcement Expires:  January 6, 2022


Title: Disseminating and Implementing Patient-Centered Outcomes Research (PCOR) Evidence into Practice through Interoperable Clinical Decision Support (R18 Research Demonstration and Disseminations Projects)
Announcement Number: PA-20-074
Deadline: January 25, May 25, September 25
Purpose: This Funding Opportunity Announcement invites R18 grant applications that disseminate and implement patient-centered outcomes research evidence in clinical practice by scaling computer-based, interoperable clinical decision support.
Award: The total costs (direct and indirect) for a project awarded under this FOA will not exceed $1,000,000 in any given year and $3 million for the entire project period.
Eligibility & Guidelines: Here
Announcement Expires:  January 26, 2022


Title: Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R01 Research Project Grant)
Announcement Number: PAR-20-276
Deadline: February 5, June 5, October 5
Purpose: Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) along with the National Human Genome Research Institute (NHGRI) and National Institute of Dental and Craniofacial Research (NIDCR) encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate the genetic architecture of cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer genomic and epidemiology by supporting the analysis of existing genetic or genomic datasets, in combination with other omics and environmental, clinical, behavioral, lifestyle, and molecular profiles data. Applicants are encouraged to leverage existing genetic data and perform innovative analyses of the existing data. Applications may include new research aims that are being addressed with existing data, new or advanced methods of analyses, or novel combinations and integration of datasets that allow the exploration of important scientific questions in genomic and epidemiology cancer research.
Award: The budget is limited to $350,000 direct costs per year and should reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: September 8, 2022


Title: Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R21 Exploratory/Developmental Research Grant)
Announcement Number: PAR-20-277
Deadline: February 16, June 16, October 16
Purpose: Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) along with the National Human Genome Research Institute (NHGRI) and National Institute of Dental and Craniofacial Research (NIDCR) encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate the genetic architecture of cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer genomic and epidemiology by supporting the analysis of existing genetic or genomic datasets, in combination with other omics and environmental, clinical, behavioral, lifestyle, and molecular profiles data. Applicants are encouraged to leverage existing genetic data and perform innovative analyses of the existing data. Applications may include new research aims that are being addressed with existing data, new or advanced methods of analyses, or novel combinations and integration of datasets that allow the exploration of important scientific questions in genomic and epidemiology cancer research.
Award: Direct costs are limited to $275,000 over a two-year project period, with no more than $200,000 in direct costs allowed in any single year.
Eligibility & Guidelines: Here
Announcement Expires: September 8, 2022


Title: Biologic Factors Underlying Dental, Oral, and Craniofacial Health Disparities (R21 Exploratory/Developmental Research Grant)
Announcement Number: PA-18-874
Deadline: February 16, June 16, October 16
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to support exploratory/developmental, investigator-initiated studies designed to identify and understand biologic factors (microbial, immune, genetic) that contribute to disparities in dental, oral, and craniofacial disease onset, progression, and persistence.
Award: The combined budget for direct costs for the two year project period may not exceed $275,000. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: September 8, 2021


Title: Biologic Factors Underlying Dental, Oral, and Craniofacial Health Disparities (R01 Research Project Grant)
Announcement Number: PAR-18-875
Deadline: February 5, June 5, October 5
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to support investigator-initiated studies designed to identify and understand biologic factors (microbial, immune, genetic) that contribute to disparities in dental, oral, and craniofacial disease onset, progression, and persistence.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: September 8, 2021


Title: Improving oral health and reducing disparities in adolescents (R01 Research Project Grant)
Announcement Number: PAR-20-058
Deadline: February 5, June 5, October 5
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research to improve the oral health of adolescents in the United States, and to reduce observed oral health disparities and inequities in this population. This FOA defines “adolescents” as those individuals between the ages of 10 and 19.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2023


Title: NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Small Grant Program)
Announcement Number: PA-20-046
Deadline: February 16, June 16, October 16
Purpose: The purpose of this FOA is to announce support for meritorious research projects that address research questions relevant to human dental, oral, or craniofacial (DOC) conditions or traits through analysis of existing and publicly available genomics data using statistical and computational approaches. Data analysis for each project can be performed using existing and/or novel methods to be developed in the same project, including machine learning-based methods (ML).
Award: The combined budget for direct costs for the two year project period may not exceed $200,000. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2023


Title: Improving oral health and reducing disparities in adolescents (R21 Exploratory/Developmental Research Grant)
Announcement Number: PA-20-059
Deadline: February 16, June 16, October 16
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to encourage exploratory or developmental research to improve the oral health of adolescents in the United States, and to reduce observed oral health disparities and inequities in this population. This FOA defines “adolescents” as those individuals between the ages of 10 and 19.
Award: The combined budget for direct costs for the two year project period may not exceed $275,000. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2023


Title: NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Research Project – Cooperative Agreements)
Announcement Number: PA-20-060
Deadline: February 5, June 5, October 5
Purpose: This Funding Opportunity Announcement (FOA) will support, through the cooperative agreement mechanism, investigator-initiated observational studies or biomarker validation studies that require prospective collection of data/biospecimens or continued analysis of data/biospecimens collected as part of a previous NIDCR award.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project. A project duration of up to five years may be requested.
Eligibility & Guidelines: Here
Announcement Expires: January 10, 2023


Title: Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19)
Announcement Number: NOT-DE-21-001
Deadline: Beginning June 05, 2021
Purpose: The National Institute of Dental and Craniofacial Research (NIDCR) is issuing this Notice of Special Interest (NOSI) to encourage research studies focused on the physiological involvement of oral cavity and oral manifestations related to SARS-CoV-2 and/or Coronavirus Disease 2019 (COVID-19).
Globally, the death toll for COVID-19 caused by the coronavirus SARS-CoV-2 has surpassed 1.9 million, and in the United States, more than 375,000 individuals have succumbed to the disease as of January 2021. Synergizing with a myriad of initiatives across NIH and responding to a palpable sense of public health urgency, NIDCR is positioned to address COVID-19 research knowledge gaps unique to our mission, as well as to facilitate broad and rapid dissemination of research findings. Outcomes from this NOSI are expected to strengthen the knowledge base of COVID-19 disease mechanisms and presentations in the oral cavity.
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: NIH Research Project Grant (R01 Research Grant)
Announcement Number: PA-20-185
Deadline: February 5, June 5, October 5
Purpose: The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Small Grant Program)
Announcement Number: PA-20-046
Deadline: February 16, June 16, October 16
Purpose: The purpose of this FOA is to announce support for meritorious research projects that address research questions relevant to human dental, oral, or craniofacial (DOC) conditions or traits through analysis of existing and publicly available genomics data using statistical and computational approaches. Data analysis for each project can be performed using existing and/or novel methods to be developed in the same project, including machine learning-based methods (ML).
Award: The combined budget for direct costs for the two year project period may not exceed $200,000. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2023


Title: NIH Exploratory/Developmental Research Grant Program (R21 Research Grant)
Announcement Number: PA-20-195
Deadline: February 16, June 16, October 16
Purpose: The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
Award: The combined budget for direct costs for the two-year project period may not exceed $275,000. No more than $200,000 may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: NIH Support for Conferences and Scientific Meetings (R13)
Announcement Number: PA-21-151
Deadline: April 12, August 12, December 12
Purpose: The purpose of the NIH Research Conference Grant (R13) is to support high quality conferences that are relevant to the public health and to the scientific mission of the participating Institutes and Centers.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project. The appropriate NIH Conference Grant Contact should be consulted for guidance regarding any IC-specific budget limitations.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2024


Title: Using Innovative Digital Healthcare Solutions to Improve Quality at the Point of Care (R21/R33 Phased Innovation Award)
Announcement Number: PA-21-164
Deadline: February 16, June 16, October 16
Purpose: The Agency for Healthcare Research and Quality’s (AHRQ) mission is to produce evidence to make health care safer, of higher quality, more accessible, equitable, and affordable, and to work within the U.S. Department of Health and Human Services and with other partners to make sure that the evidence is understood and used. This FOA invites applications that propose research projects that test promising digital healthcare interventions aimed at improving quality of care and healthcare services delivery at the point of care. This FOA will use the Phased Innovation Award (R21/R33) mechanism to provide up to 2 years of R21 support for initial developmental activities, and up to 3 years of R33 support for expanded activities. Transition to the R33 phase is not guaranteed for all grants awarded under this FOA. Continuation from the R21 phase to the R33 phase will be determined by AHRQ staff based on progress achieved in the R21 phase and factors such as program priorities and availability of funds.
Award: In the R21 phase, the combined budget for total costs (direct and indirect) for the two-year period may not exceed $275,000. No more than $200,000 total costs may be budgeted in either year of the R21 phase. In the R33 phase, the combined budget for total costs (direct and indirect) for the three-year period may not exceed $750,000. No more than $300,000 total costs may be budgeted in any given year.
Eligibility & Guidelines: Here
Announcement Expires: July 18, 2024


Title: NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award)
Announcement Number: PAR-21-060
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00) is to support outstanding graduate students from diverse backgrounds, including those from groups underrepresented in biomedical, clinical, behavioral and social sciences, over the transition from predoctoral to postdoctoral research training. This phased award program will facilitate completion of graduate PhD or dual degree clinician scientist programs (F99) and progression to mentored postdoctoral positions in dental, oral and craniofacial research (K00). It is anticipated that successful completion of this phased award program will enable achievement of an independent research faculty position and subsequent NIDCR career development and research project awards.
Award: For the F99 phase, award budgets are composed of stipends, tuition and fees, and institutional allowance, as described below. For the K00 phase, award budgets are composed of salaries and fringe benefits, research and career development support, and indirect costs, as described below. For the F99/K00 award, individuals may receive up to 5 years combined support for both phases, which includes up to 2 years in the F99 fellowship phase and up to 3 years in the K00 career development phase.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2024


Title: Notice of Special Interest: Administrative Supplements to Support Dentist Scientists Post Specialty or Residency to Develop Expertise in Dental, Oral and Craniofacial Research
Announcement Number: NOT-DE-20-035
Deadline: Varies
Purpose: The purpose of the NIDCR Dentist Scientist Administrative Supplement Program is to enhance the research careers of dentist-scientists who can contribute vital clinical perspectives to dental, oral and craniofacial research projects, and to build and sustain a dentist-scientist research workforce dedicated to improving dental, oral and craniofacial health. The program will provide supplemental funds to active NIDCR research grants to support mentored research experiences for outstanding early career dentist-scientists who have recently completed dental specialty or residency training. The program is intended to accelerate the candidate’s transition from primarily clinical activities to predominantly research activities by providing protected time to develop or update research skills, formulate a research career plan, generate preliminary data and seek independent funding. Dentist scientist candidates for this program are expected to contribute substantially to on-going research by conducting well-defined projects that are within scope of the goals and objectives of the parent grant. The candidate’s research experience is expected to be guided by an experienced investigator(s) and provide a foundation for the candidate’s future research independence. Mentors are expected to work with candidates to develop research experience plans that include the preparation of an independent grant application for NIDCR support and are anticipated to enhance the candidate’s successful competition for independent research support. An initial request for one year of supplement support will be allowed, with the expectation that the candidate will make research progress and begin preparation of a grant application. An application for a second consecutive year of supplement support will be considered if progress in the initial year is demonstrated, and the need for an additional year of support to achieve the proposed career development goals and submission of an application for an independent support is strongly justified.
Award: The NIDCR will provide support for the candidate’s annual salary, in accordance with the salary structure of the grantee institution, and consistent with the level of effort, up to $100,000 per year plus allowable fringe benefits. The total salary requested for the candidate must be established on the base salary of a full-time, 12-month staff appointment. The supplement budget may request up to $25,000 per year for additional research-related costs such as laboratory supplies and core services, as well as costs for the candidate’s travel to a scientific conference. The duration of an initial supplement request must be one year. The parent award must have at least one year, or two or more years remaining on the project period at the time of supplement award. Two or more years would allow a potential second supplement application.
Eligibility & Guidelines: Here
Announcement Expires: July 24, 2023


Title: Notice of Special Interest (NOSI): Simulation Modeling and Systems Science to Address Health Disparities
Announcement Number: NOT-MD-20-025
Deadline: Varies
Purpose: The purpose of this Notice of Special Interest is to support investigative and collaborative research focused on developing and evaluating simulation modeling and systems science to understand and address minority health and health disparities.
Award: Varies
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: Innovative Research in Cancer Nanotechnology (IRCN) (R01 Research Project Grant)
Announcement Number: PAR-20-284
Deadline: Varies
Purpose: This Funding Opportunity Announcement (FOA) entitled “Innovative Research in Cancer Nanotechnology (IRCN)” encourages applications promoting transformative discoveries in cancer biology and/or oncology through the use of nanotechnology. Proposed projects should address major barriers in cancer biology and/or oncology using nanotechnology and should focus on mechanistic studies to expand the fundamental understanding of nanomaterial and/or nano-device interactions with biological systems. These studies are expected to be relevant to the delivery of nanoparticles and/or nano-devices to desired and intended cancer targets in vivo and/or characterization of detection and diagnostic devices and sensors in vitro. IRCN awards are expected to produce fundamental knowledge to aid future and more informed development of nanotechnology-based cancer interventions.
Award: Application budgets are limited to $450K in direct costs per year and need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: May 5, 2023


Title: Notice of Special Interest (NOSI): Development and Preliminary Testing of Health-related Behavioral Interventions
Announcement Number: NOT-OD-20-106
Deadline: Varies
Purpose: This Notice encourages translational behavioral intervention research, integrated with basic behavioral and social science, aimed at creating, refining, and testing novel interventions focused on the initiation, cessation, or maintenance of behaviors associated with improved health or disease mitigation.
The behavioral, emotional, cognitive, and/or social targets for the intervention/s being developed and tested in response to this NOSI, should be based on insights from basic science about mechanisms that underlie health-related behavior change. Interventions may target the individual (e.g., cognitive or psychological processes), the immediate social environment (e.g., dyadic or family relationships), and/or broader social, organizational or environmental systems (e.g., worksites, schools, healthcare delivery, or neighborhood features).
Eligibility & Guidelines: Here
Announcement Expires: September 26, 2022


Title: Notice of Special Interest (NOSI) of NIDCR in Supporting Dental, Oral, and Craniofacial Research Using Bioinformatic, Computational, and Data Science Approaches
Announcement Number: NOT-DE-20-006
Deadline: Varies
Purpose: The volume, dimension, and complexity of biomedical and behavioral research data are expanding rapidly, requiring bioinformatic, computational, and data science approaches to manage and analyze the data, address new questions, and obtain deeper insight from the data. This Notice of Special Interest (NOSI) calls for research and research training projects that focus on dental, oral, and craniofacial biology and diseases using bioinformatic, computational, and data science approaches.
Eligibility & Guidelines: Here
Announcement Expires: August 08, 2023


Title: Enabling Technologies to Accelerate Development of Oral Biodevices (R21 Research Grant)
Announcement Number: PAR-20-232
Deadline: February 16, June 16, October 16
Purpose: This Funding Opportunity Announcement (FOA) invites exploratory/developmental applications that propose transformative engineering solutions to technical challenges associated with meaningful development, substantial optimization of existing technologies and clinical translation of intraoral biodevices. Proposed technologies are expected to advance development of oral biodevices to clinical use, including but not limited to: precision medicine-based detection, diagnosis and treatment of oral and overall health conditions, and measurement of patient functional status and clinical outcome assessment. Areas of interest in this FOA include engineering approaches that allow integration of electronic, physical, and biological systems essential to the development of functional biodevices that are safe and effective for detection, diagnosis and treatment of oral and systemic disease. Products of this research will be proof-of-concept prototype biodevices, dedicated biosensors and associated core technologies that enable development of safe and effective intra-oral biodevices intended for specific clinical applications. To streamline the development of oral biodevices that advance precision medicine-based approaches in clinical practice, this FOA encourages interdisciplinary collaborations across engineering, multifunctional sensors, pharmacology, chemistry, medicine, and dentistry, as well as between academia and industry.
Award: Direct costs are limited to $275,000 over a two-year project period, with no more than $200,000 in direct costs allowed in any single year.
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: Enabling Technologies to Accelerate Development of Oral Biodevices (R01 Research Grant)
Announcement Number: PAR-20-233
Deadline: February 5, June 5, October 5
Purpose: This Funding Opportunity Announcement (FOA) invites applications that propose transformative engineering solutions to technical challenges associated with new development, substantial optimization of existing technologies and clinical translation of intraoral biodevices. Proposed technologies are expected to advance development of oral biodevices for clinical use, including but not limited to: precision medicine-based detection, diagnosis and treatment of oral and overall health conditions, and measurement of patient functional status and clinical outcome assessment. Areas of interest in this FOA include engineering approaches that allow integration of electronic, physical, and biological systems into functional biodevices that are safe and effective for detection, diagnosis and treatment of oral and systemic disease. Products of this research will be functional biodevices and integrated approaches thoroughly characterized to demonstrate preclinical safety and effective performance in support of specific intended clinical applications. To streamline the development of oral biodevices that advance precision medicine-based approaches in clinical practice, this FOA encourages interdisciplinary collaborations across engineering, multifunctional sensors, pharmacology, chemistry, medicine, and dentistry, as well as between academia and industry.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: Notice of Special Interest: Health Services Research on Minority Health and Health Disparities (R01 Research Project Grant)
Announcement Number: NOT-MD-20-011
Deadline: February 5, June 5, October 5
Purpose: The purpose of this Notice of Special Interest is to encourage innovative health services research that can directly and demonstrably contribute to the improvement of minority health and/or the reduction of health disparities at the health care system-level as well as within clinical settings.
Eligibility & Guidelines: Here
Announcement Expires:  September 08, 2022


Title: Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Research Project Grant)
Announcement Number: PAR-20-155
Deadline: February 5, June 5, October 5
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to stimulate translation of scientific discoveries and engineering developments in imaging, data science and/or spectroscopic technologies into methods or tools that address contemporary problems in understanding the fundamental biology, potential risk of development, diagnosis, treatment, and/or disease status for cancer or other disease. A distinguishing feature of each application to this FOA will be formation of an academic-industrial partnership: a strategic alliance of academic and industrial investigators who work together as partners to identify and translate a technological solution for mitigation of a cancer (or other disease-related) problem. In this sense, the FOA acts more as funding mechanism for driving translational research in imaging more than for a specific scientific or clinical research area. These partnerships are expected to solidify pre-existing collaborations or new ones that would drive the field of imaging, as a whole, further than if they had not been formed. This FOA defines innovation as likelihood to deliver a new capability to end users. This FOA will support clinical trials that test functionality, or validate performance in the chosen setting. This FOA is not intended to support commercial production, basic research projects, or clinical trials that lack translation as the primary motivation.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires:  September 08, 2022


Title: Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Research Project Grant)
Announcement Number: PAR-20-131
Deadline: February 5, June 5, October 5
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for projects to expand, improve, or transform the utility of mammalian cancer and tumor models for translational research.
With this FOA, the NCI intends to encourage submission of projects devoted to demonstrating that mammalian models or their derivatives used for translational research are robust representations of human biology, are appropriate to test questions of clinical importance, and provide reliable information for patients’ benefit. These practical goals contrast with the goals of many mechanistic, NCI-supported R01 projects that use mammals, or develop and use mammalian cancer models, transplantation tumor models, or models derived from mammalian or human tissues or cells for hypothesis-testing, non-clinical research. Among many other possible endeavors, applicants in response to this FOA could propose demonstrations of how to overcome translational deficiencies of mammalian oncology models, define new uses of mammalian models or their genetics for unexplored translational challenges, advance standard practices for use of translational models, test approaches to validate and credential models, or challenge current practices for how models are used translationally.
Award: Application budgets are limited to $450,000 direct costs per year.
Eligibility & Guidelines: Here
Announcement Expires:  May 8, 2023


Title: National Dental Practice-Based Research Network Infrastructure Access (X01 Resource Access Award)
Announcement Number: PAR-20-073
Deadline: September 1, 2021; September 1, 2022
Purpose: The National Institute of Dental and Craniofacial Research (NIDCR) is continuing support for research conducted within a dental Practice-Based Research Network (PBRN). The National Dental PBRN Administrative and Resource Center and National Coordinating Center support the infrastructure for and implementation of multiple clinical studies. This Funding Opportunity Announcement (FOA) is seeking applications for small developmental/exploratory, feasibility (pilot), and/or survey studies of practitioners and/or patients to be conducted in the National Dental PBRN. Successful X01 applicants will be given access to the National Dental PBRN infrastructure to support an individual project. Successful applications will utilize the resources of and be funded through the National Dental PBRN Administrative and Resource Center and/or National Coordinating Center for study planning and implementation. This FOA seeks projects up to two years in length. The main goals of the dental PBRN are to streamline the implementation of national oral health research studies in dental practices on topics of importance to practitioners and their patients, to provide evidence useful in daily patient care, and to facilitate the translation of research findings into clinical practice. This FOA encourages applications proposing research studies that align with the goals of the dental PBRN.
Award: There is no budget associated with X01 Resource Access Awards.
Eligibility & Guidelines: Here
Announcement Expires:  September 2, 2022


Title: Biomedical Data Repository (U24 Resource-Related Research Projects – Cooperative Agreements)
Announcement Number: PAR-20-089
Deadline: January 25, 2021; September 24, 2021; January 25, 2022; September 26, 2022; January 25, 2023
Purpose: This funding opportunity announcement is designed to support biomedical data repositories. Biomedical data repositories under this announcement should have the primary function to ingest, archive, preserve, manage, distribute, and make accessible the data related to a particular system or systems. Support for data curation must be limited to that which improves the efficiency and accessibility of data ingestion, management, and use and reuse by the user communities. Support for software and tool development must be limited to that which provides essential functions or significantly increases the efficiency of operation of the repository. Applications that have a significant focus on software and tool development are not appropriate for this activity.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires:  May 09, 2023


Title: National Cancer Institute Program Project Applications (P01 Research Program Projects)
Announcement Number: PAR-20-077
Deadline: January 25, May 25, September 25
Purpose: With this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites applications for investigator-initiated Program Project (P01) applications. The proposed Program may address any of the broad areas of cancer research, including (but not limited to) cancer biology, cancer prevention, cancer diagnosis, cancer treatment, and cancer control. Basic, translational, clinical, and/or population-based studies in all of these research areas are appropriate. Each application submitted in response to this FOA must consist of at least three research projects and an Administrative Core. The projects must share a common central theme, focus, and/or overall objective.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: May 8, 2023


Title: Improving oral health and reducing disparities in adolescents (R01)
Announcement Number: PAR-20-058
Deadline: February 5, June 5, October 5
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research to improve the oral health of adolescents in the United States, and to reduce observed oral health disparities and inequities in this population. This FOA defines “adolescents” as those individuals between the ages of 10 and 19.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project. The maximum project period is 5 years.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2023


Title: Improving oral health and reducing disparities in adolescents (R21)
Announcement Number: PAR-20-059
Deadline: February 16, June 16, October 16
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to encourage exploratory or developmental research to improve the oral health of adolescents in the United States, and to reduce observed oral health disparities and inequities in this population. This FOA defines “adolescents” as those individuals between the ages of 10 and 19.
Award: The combined budget for direct costs for the two year project period may not exceed $275,000. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2023


Title: NIDCR Small Grant Program for New Investigators (R03)
Announcement Number: PAR-19-370
Deadline: February 16, June 16, October 16
Purpose: The NIDCR Small Grant Program for New Investigators (R03) supports basic and clinical research conducted by scientists who are in the early stages of establishing an independent research career in oral, dental and craniofacial research. This program supports pilot or feasibility studies and developmental research projects with the intention of obtaining sufficient preliminary data for a subsequent investigator initiated Research Project Grant (R01) or equivalent application.
Award: A budget for direct costs of up to $200,000 may be requested. Application budgets should not exceed $100,000 in direct costs in either year.
Eligibility & Guidelines: Here
Announcement Expires:  September 8, 2022


Title: NIDA Research Center of Excellence Grant Program (P50 Clinical Trial Optional)
Announcement Number: PAR-19-259
Deadline: September 25, 2021
Purpose: This Funding Opportunity Announcement (FOA) is to provide support for research Centers that (1) conduct drug abuse and addiction research in any area of NIDA’s mission, (2) have outstanding innovative science, (3) are multidisciplinary, thematically integrated, synergistic, and (4) serve as national resource(s) to provide educational and outreach activities to drug abuse research communities, educational organizations, the general public, and policy makers in the NIDA research fields. It is expected that a Center will transform knowledge in the sciences it is studying. Incremental work should not be the focus of Center activities; rather, new and creative directions are required. The P50 Center of Excellence is expected to foster the career development and mentoring of new investigators who would be given meaningful roles to play in the Center projects. A goal of this program is to create NIDA Centers that are national community resources for furthering drug abuse research by sharing their findings, their data, and their resources as appropriate for researchers to use and build upon and to advance research in this field.
Award: Application budgets for direct costs cannot exceed $10,000,000 for the entire 5 year project period including no cost extensions, but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2022


Title: Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42)
Announcement Number: PA-19-021
Deadline: September 5, January 5, April 5
Purpose: This Funding Opportunity Announcement (FOA) encourages innovation, optimization and customization of core technologies in digital dentistry that improve efficiency of oral healthcare delivery, effectiveness of clinical decision-making and outcomes of treatments associated with dental, oral and craniofacial (DOC) tissues. Among the areas of interest of this FOA are development of digital imaging and image processing capabilities for dental radiology, and the integration of 3-dimensional (3D) additive manufacturing (e.g., 3D printing) with imaging tools. This FOA also supports efforts to develop, integrate, adapt, optimize, and validate new and existing dental materials designed for additive manufacturing approaches in the repair, replacement and restoration of DOC tissues.
Award: According to statutory guidelines, total funding support (direct costs, indirect costs, fee) normally may not exceed $150,000 for Phase I awards and $1,000,000 for Phase II awards. With appropriate justification from the applicant, Congress will allow awards to exceed these amounts by up to 50% as a hard cap ($225,000 for Phase I and $1,500,000 for Phase II). However, NIH has received a waiver from SBA, as authorized by statute, to exceed the hard cap of $225,000 for Phase I or $1,500,000 for Phase II for specific topics. The current list of approved topics can be found at https://sbir.nih.gov/funding#omni-sbir. Applicants are strongly encouraged to contact NIH program officials prior to submitting any application in excess of the guidelines and early in the application planning process. In all cases, applicants should propose a budget that is reasonable and appropriate for completion of the research project.
Eligibility & Guidelines: Here
Announcement Expires:  September 6, 2021


Title: Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R43/R44)
Announcement Number: PA-19-022
Deadline: September 5, January 5, April 5
Purpose: This Funding Opportunity Announcement (FOA) encourages innovation, optimization and customization of core technologies in digital dentistry that improve efficiency of oral healthcare delivery, effectiveness of clinical decision-making and outcomes of treatments associated with dental, oral and craniofacial (DOC) tissues. Among the areas of interest of this FOA are development of digital imaging and image processing capabilities for dental radiology, and the integration of 3-dimensional (3D) additive manufacturing (e.g., 3D printing) with imaging tools. This FOA also supports efforts to develop, integrate, adapt, optimize, and validate new and existing dental materials designed for additive manufacturing approaches in the repair, replacement and restoration of DOC tissues.
Award: According to statutory guidelines, total funding support (direct costs, indirect costs, fee) normally may not exceed $150,000 for Phase I awards and $1,000,000 for Phase II awards. With appropriate justification from the applicant, Congress will allow awards to exceed these amounts by up to 50% as a hard cap ($225,000 for Phase I and $1,500,000 for Phase II). However, NIH has received a waiver from SBA, as authorized by statute, to exceed the hard cap of $225,000 for Phase I or $1,500,000 for Phase II for specific topics. The current list of approved topics can be found at https://sbir.nih.gov/funding#omni-sbir. Applicants are strongly encouraged to contact NIH program officials prior to submitting any application in excess of the guidelines and early in the application planning process. In all cases, applicants should propose a budget that is reasonable and appropriate for completion of the research project
Eligibility & Guidelines: Here
Announcement Expires:  September 6, 2021


Title: Enabling Technologies to Accelerate Development of Oral Biodevices (R41/R42)
Announcement Number: PA-19-075
Deadline: September 5, January 5, April 5
Purpose: This Funding Opportunity Announcement (FOA) invites applications that propose transformative engineering solutions to technical challenges associated with new development, substantial optimization of existing technologies and clinical translation of intraoral biodevices. Proposed technologies are expected to advance development of oral biodevices to clinical use, including but not limited to: precision medicine-based detection, diagnosis and treatment of oral and overall health conditions, and measurement of patient functional status and clinical outcome assessment. Areas of interest in this FOA include engineering approaches that allow integration of electronic, physical, and biological systems essential to the development of functional biodevices that are safe and effective for detection, diagnosis and treatment of oral and systemic disease. Products of this research will be proof-of-concept prototype biodevices, dedicated biosensors, associated core technologies and integrated approaches that enable development of safe and effective intra-oral biodevices intended for specific clinical applications. To streamline the development of oral biodevices that advance precision medicine-based approaches in clinical practice, this FOA encourages interdisciplinary collaborations across engineering, multifunctional sensors, pharmacology, chemistry, medicine, and dentistry, as well as between academia and industry.
Award: According to statutory guidelines, total funding support (direct costs, indirect costs, fee) normally may not exceed $150,000 for Phase I awards and $1,000,000 for Phase II awards. With appropriate justification from the applicant, Congress will allow awards to exceed these amounts by up to 50% as a hard cap ($225,000 for Phase I and $1,500,000 for Phase II). However, NIH has received a waiver from SBA, as authorized by statute, to exceed the hard cap of $225,000 for Phase I or $1,500,000 for Phase II for specific topics. The current list of approved topics can be found at https://sbir.nih.gov/funding#omni-sbir. Applicants are strongly encouraged to contact NIH program officials prior to submitting any application in excess of the guidelines and early in the application planning process. In all cases, applicants should propose a budget that is reasonable and appropriate for completion of the research project.
Eligibility & Guidelines: Here
Announcement Expires: January 6, 2022


Title: Enabling Technologies to Accelerate Development of Oral Biodevices (R43/R44)
Announcement Number: PA-19-076
Deadline: September 5, January 5, April 5
Purpose: This Funding Opportunity Announcement (FOA) invites applications that propose transformative engineering solutions to technical challenges associated with new development, substantial optimization of existing technologies and clinical translation of intraoral biodevices. Proposed technologies are expected to advance development of oral biodevices to clinical use, including but not limited to: precision medicine-based detection, diagnosis and treatment of oral and overall health conditions, and measurement of patient functional status and clinical outcome assessment. Areas of interest in this FOA include engineering approaches that allow integration of electronic, physical, and biological systems essential to the development of functional biodevices that are safe and effective for detection, diagnosis and treatment of oral and systemic disease. Products of this research will be proof-of-concept prototype biodevices, dedicated biosensors, associated core technologies and integrated approaches that enable development of safe and effective intra-oral biodevices intended for specific clinical applications. To streamline the development of oral biodevices that advance precision medicine-based approaches in clinical practice, this FOA encourages interdisciplinary collaborations across engineering, multifunctional sensors, pharmacology, chemistry, medicine, and dentistry, as well as between academia and industry.
Award: According to statutory guidelines, total funding support (direct costs, indirect costs, fee) normally may not exceed $150,000 for Phase I awards and $1,000,000 for Phase II awards. With appropriate justification from the applicant, Congress will allow awards to exceed these amounts by up to 50% as a hard cap ($225,000 for Phase I and $1,500,000 for Phase II). However, NIH has received a waiver from SBA, as authorized by statute, to exceed the hard cap of $225,000 for Phase I or $1,500,000 for Phase II for specific topics. The current list of approved topics can be found at https://sbir.nih.gov/funding#omni-sbir. Applicants are strongly encouraged to contact NIH program officials prior to submitting any application in excess of the guidelines and early in the application planning process. In all cases, applicants should propose a budget that is reasonable and appropriate for completion of the research project.
Eligibility & Guidelines: Here
Announcement Expires: January 6, 2022


Title: NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03)
Announcement Number: PAR-19-145
Deadline: February 16, June 16, October 16
Purpose: The goal of this funding opportunity announcement is to support meritorious research projects that involve secondary data analyses of existing oral or craniofacial database resources, or to develop needed statistical methodology for analyzing oral and craniofacial data using existing oral or craniofacial databases. The R03 grant mechanism supports research limited in time and amount for studies in categorical program areas.
Award: A budget for direct costs of up to $100,000 per year, with a maximum of $200,000 direct costs over two years, may be requested.
Eligibility & Guidelines: Here
Announcement Expires: January 8, 2022


Title: Mechanistic Studies of Gene-Environment Interplay in Dental, Oral, Craniofacial, and Other Diseases and Conditions (R01)
Announcement Number: PAR-19-292
Deadline: February 5, June 5, October 5
Purpose: This Funding Opportunity Announcement (FOA) is intended to foster research towards a better understanding of the biological mechanisms of gene-environment interplay in human diseases and conditions. Through this FOA, the NIDCR, NIEHS, and NICHD solicit applications that use animal models, in vitro systems, or ex vivo approaches to conduct mechanistic investigation of the interplay of genes/gene networks and environmental factors in dental, oral, craniofacial (DOC), and other diseases and conditions.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: September 8, 2022


Title: Development of Novel and Robust Systems for Mechanistic Studies of Gene-Environment Interplay in Dental, Oral, Craniofacial, and Other Diseases and Conditions (R21)
Announcement Number: PAR-19-293
Deadline: February 16, June 16, October 16
Purpose: This Funding Opportunity Announcement (FOA) is intended to foster research towards a better understanding of the biological mechanisms of gene-environment interplay in human diseases and conditions. Through this FOA, the NIDCR, NIEHS , and NICHD solicit applications to develop novel and robust experimental systems that offer approaches complementary to human epidemiologic or in vivo studies to facilitate mechanistic investigation of gene-environment interplay in dental, oral, craniofacial, and other diseases and conditions.
Award: The combined budget for direct costs for the two year project period may not exceed $275,000. No more than $200,000 may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: September 8, 2022


Title: Precision Imaging of Oral Lesions (R01/R21)
Announcement Number: PAR-18-787 (R01)/PAR-18-788 (R21)
Deadline: R01: February 5, June 5, October 5 / R21: February 16, June 16, October 16
Purpose: The intent of this Funding Opportunity Announcement (FOA) is to advance the development, adaptation, optimization, and validation of accurate, reproducible, specific, and sensitive imaging approaches to improve diagnosis, treatment, and treatment monitoring for diseases and conditions in the oral cavity and oropharynx.
Award: Direct costs are limited to $275,000 over a two-year project period, with no more than $200,000 in direct costs allowed in any single year.
Eligibility & Guidelines: Here
Announcement Expires: September 8, 2021


Title: Biologic Factors Underlying Dental, Oral, and Craniofacial Health Disparities (R01/R21)
Announcement Number: PA-18-874
Deadline: R01: February 5, June 5, October 5 / R21: February 16, June 16, October 16
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to support exploratory/developmental, investigator-initiated studies designed to identify and understand biologic factors (microbial, immune, genetic) that contribute to disparities in dental, oral, and craniofacial disease onset, progression, and persistence.
Award: The combined budget for direct costs for the two-year project period may not exceed $275,000. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: September 8, 2021


Title: Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01)
Announcement Number: PA-18-876
Deadline: February 5, June 5, October 5
Purpose: The purpose of this funding opportunity announcement (FOA) is twofold: (1) to stimulate basic and mechanistic science that facilitates the development of effective probiotics or pre-/probiotic combinations of relevance to human health and disease; and (2) determine biological outcomes for the evaluation of efficacy of pre/probiotics in appropriate test systems and animal models. This FOA encourages basic and mechanistic studies using in vitro, in vivo, ex vivo, and in silico models that focus on prebiotic/probiotic strain selectivity, interaction, and function. It will also encourage inter and multidisciplinary collaborations among scientists in a wide range of disciplines including nutritional science, immunology, microbiomics, genomics, other ‘-omic’ sciences, biotechnology, and bioinformatics.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: September 8, 2021


Title: Clinical Research to Improve the Oral Health of Older Adults (R21)
Announcement Number: PAR-19-240
Deadline: February 16, June 16, October 16
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to encourage exploratory or developmental research to address risk factors, access to care barriers, oral health promotion and disease prevention strategies, and clinical management of dental, oral, and craniofacial (DOC) diseases more commonly experienced by older adults. This FOA defines “older adults” as those individuals age 65 years and older.
Award: The combined budget for direct costs for the two-year project period may not exceed $275,000 direct costs. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires:  September 8, 2022


Title: Clinical Research to Improve the Oral Health of Older Adults (R01)
Announcement Number: PAR-19-239
Deadline: February 5, June 5, October 5
AIDS Dates: May 7, 2020; September 7, 2020; January 7, 2021; May 7, 2021; September 7, 2021; January 7, 2022; May 7, 2022; September 7, 2022
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research to address gaps in our knowledge related to the risk factors, access to care barriers, oral health promotion and disease prevention strategies, and clinical management of dental, oral, and craniofacial (DOC) diseases more commonly experienced by older adults. This FOA defines “older adults” as those individuals age 65 years and older.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project. The maximum project period is 5 years.
Eligibility & Guidelines: Here
Announcement Expires:  September 7, 2022


Title: NIDCR Small Grant Program for New Investigators (R03 Small Grant Program)
Announcement Number: PAR-21-084
Deadline: February 16, June 16, October 16
Purpose: This NIDCR Small Grant Program for New Investigators supports basic and clinical research conducted by scientists who are in the early stages of establishing an independent research career in oral, dental and craniofacial research. This R03 program supports pilot or feasibility studies and developmental research projects with the intention of obtaining sufficient preliminary data for a subsequent investigator¬ initiated Research Project Grant (R01) or equivalent application.
Award: A budget for direct costs of up to $200,000 may be requested. Application budgets should not exceed $100,000 in direct costs in either year.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2024


Training (K Announcements)

Title: Mentored Research Scientist Development Award (K01 Training Grant)
Announcement Number: PA-20-190
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and “protected time” (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances..
This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion FOA.
Award: Award budgets are composed of salary and other program-related expenses.
Eligibility & Guidelines: Here
Announcement Expires: May 8, 2023


Title: Mentored Quantitative Research Development Award (K25 Training Grant)
Announcement Number: PA-20-199
Deadline: March 12, July 12, November 12
Purpose: The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and “protected time” for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.
This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator should apply to the companion FOA (PA-20-197).
Award: Award budgets are composed of salary and other program-related expenses.
Eligibility & Guidelines: Here
Announcement Expires: May 8, 2023


Title: Mentored Clinical Scientist Research Career Development Award (K08)
Announcement Number: PA-19-117
Deadline: February 12, June 12, October 12
Purpose: The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program represents the continuation of a long-standing NIH program that provides support and “protected time” to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research.
This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion FOA (PA-19-116).
Award: Award budgets are composed of salary and other program-related expenses.
Eligibility & Guidelines: Here
Announcement Expires: January 8, 2022


Title: Short-term Mentored Career Enhancement Award in Dental, Oral and Craniofacial Research for Mid-Career and Senior Investigators (K18 Career Enhancement Award)
Announcement Number: PAR-19-238
Deadline: February 12, June 12, October 12
Purpose: This Funding Opportunity Announcement (FOA) encourages applications for short-term mentored career enhancement (K18) awards in dental, oral and craniofacial (DOC) research with a focus on behavioral and social sciences, and on genetics, genomics, bioinformatics and computational biology research. The intent of this program is to provide mid-career and senior investigators with short-term training in the theories, tools, methods or approaches of another scientific area, in order to enhance their existing research program. Two categories of candidates are targeted: (a) established DOC research investigators who seek training with investigators from another field, in order to enrich their existing DOC research program; and (b) established investigators in other fields who seek training with DOC research investigators in order to facilitate the introduction of DOC research into an existing research program.
This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor.
Award: Award budgets are composed of salary and other program-related expenses, as described below. A project period from 2.5 months to 12 months may be requested.
Eligibility & Guidelines: Here
Announcement Expires:  May 8, 2022


Title: Midcareer Investigator Award in Patient-Oriented Research (K24)
Announcement Number: PA-19-122
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-professional doctorates for protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for clinical residents, clinical fellows and/or junior clinical faculty.
This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by another investigator. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion FOA (PA-19-121).
Award: Award budgets are composed of salary and other program-related expenses.
Eligibility & Guidelines: Here
Announcement Expires: January 8, 2022


Title: Mentored Patient-Oriented Research Career Development Award (K23)
Announcement Number: PA-19-119
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of individuals with a clinical doctoral degree who have made a commitment to focus their research endeavors on patient-oriented research.
This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion FOA (PA-19-118).
Award: Award budgets are composed of salary and other program-related expenses.
Eligibility & Guidelines: Here
Announcement Expires: January 8, 2022


Title: NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00)
Announcement Number: PAR-19-144
Deadline: February 12, June 12, October 12
Purpose: This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion FOA (PAR-18-432). Applicants proposing basic experimental studies in humans referred to in NOT-OD-18-212 as “prospective basic science studies involving human participants” should apply to the companion Basic Experimental Studies with Humans FOA (PAR-19- 141).
The purpose of the NIDCR Dentist Scientist Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented independent dual degree dentist scientists. This program is designed to facilitate a timely transition of outstanding dual degree dentist scientists from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions by providing support for two years of mentored training and three to five years of independent research. The option for five years of independent (R00) support is available to accommodate clinical training in an advanced specialty education program at no more than 3 person-months effort (25% effort) in any year of the R00 phase.
Award: Award budgets are composed of salary and other program-related expenses.
Eligibility & Guidelines: Here
Announcement Expires: January 8, 2022


Title: NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Individual Predoctoral to Postdoctoral Transition Award)
Announcement Number: PAR-20-069
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00) is to support outstanding graduate students from diverse backgrounds, including those from groups underrepresented in biomedical, clinical, behavioral and social sciences, over the transition from predoctoral to postdoctoral research training.. This phased award program will facilitate completion of graduate PhD or dual degree clinician scientist programs (F99) and progression to mentored postdoctoral positions in dental, oral and craniofacial research (K00). It is anticipated that successful completion of this phased award program will enable achievement of an independent research faculty position and subsequent NIDCR career development and research project awards. This Funding Opportunity Announcement (FOA) does not allow prospective fellows to propose to lead an independent clinical trial, but does allow prospective fellows to propose research experience in a clinical trial led by a sponsor or co-sponsor.
Award: For the F99 phase, award budgets are composed of stipends, tuition and fees, and institutional allowance, as described below.
For the K00 phase, award budgets are composed of salaries and fringe benefits, research and career development support, and indirect costs, as described below.
Eligibility & Guidelines: Here
Announcement Expires: January 8, 2023


Title: NIDCR Small Grant Program for New Investigators (R03 Small Grant Program)
Announcement Number: PAR-21-084
Deadline: February 16, June 16, October 16
Purpose: This NIDCR Small Grant Program for New Investigators supports basic and clinical research conducted by scientists who are in the early stages of establishing an independent research career in oral, dental and craniofacial research. This R03 program supports pilot or feasibility studies and developmental research projects with the intention of obtaining sufficient preliminary data for a subsequent investigator¬ initiated Research Project Grant (R01) or equivalent application.
Award: A budget for direct costs of up to $200,000 may be requested. Application budgets should not exceed $100,000 in direct costs in either year.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2024


Title: NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award)
Announcement Number: PAR-21-060
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00) is to support outstanding graduate students from diverse backgrounds, including those from groups underrepresented in biomedical, clinical, behavioral and social sciences, over the transition from predoctoral to postdoctoral research training. This phased award program will facilitate completion of graduate PhD or dual degree clinician scientist programs (F99) and progression to mentored postdoctoral positions in dental, oral and craniofacial research (K00). It is anticipated that successful completion of this phased award program will enable achievement of an independent research faculty position and subsequent NIDCR career development and research project awards. This Funding Opportunity Announcement (FOA) does not allow applicants to propose to lead an independent clinical trial, but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor.
Award: For the F99 phase, award budgets are composed of stipends, tuition and fees, and institutional allowance, as described below. For the K00 phase, award budgets are composed of salaries and fringe benefits, research and career development support, and indirect costs, as described below.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2024


Title: NIDCR Dual Degree Dentist Scientist Predoctoral to Postdoctoral Transition Award (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award)
Announcement Number: PAR-21-108
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIDCR Dual Degree Dentist Scientist Predoctoral to Postdoctoral Transition Award (F99/K00) is to provide support and mentorship to outstanding students enrolled in integrated dual degree dental (DDS/DMD) and PhD programs during the transition from predoctoral student to postdoctoral scholar. This phased award program will facilitate completion of predoctoral dual degree dentist scientist training (F99) and progression to mentored postdoctoral positions in dental, oral and craniofacial research (K00). It is anticipated that successful completion of this phased award program will enhance dual degree dentist scientists’ research career trajectories. This Funding Opportunity Announcement (FOA) does not allow applicants to propose to lead an independent clinical trial, but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor.
Award: For the F99 phase, award budgets are composed of stipends, tuition and fees, and institutional allowance, as described below. For the K00 phase, award budgets are composed of salaries and fringe benefits, research and career development support, and indirect costs, as described below.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2024