Emily Stephen
As a member of the Department of Mathematics and Statistics, I work on statistical modeling and analysis of neural recordings across spatial scales. Propagation of electrical and magnetic fields in the brain depends on both static anatomical features and state-dependent dynamical features like coherence, neuromodulation, and active pathways. My work involves constructing models that use […]
Tuan Leng Tay
How do the different types of glial cells, such as astrocytes and microglia, support the healthy development of the brain? They are important in the maintenance and (immune) protection of our nervous system. In disease and injury, glial cells alter themselves in response to a disrupted steady state, potentially to restore health to their neuronal […]
Julia TCW
Prof. TCW is interested in understanding Alzheimer’s disease. Her research is focused on a mutant form of Apolipoprotein E (APOE), a major genetic risk factor for Alzheimer’s disease. These studies will provide an opportunity to evaluate the APOE genetic contribution to neurodegeneration associated with the disease by using brain cells derived from human induced pluripotent […]
Michael Wallace
The Wallace lab studies how specific circuits within the basal ganglia (BG) guide motivated behaviors, control goal-directed motor actions, and how these circuits are affected in disease. The lab has expertise in electrophysiology, molecular biology, genetics, in vivo optogenetics, computer programming, and in behavioral and imaging techniques. We apply these techniques and knowledge of BG […]
John White
Prof. White’s laboratory uses engineering approaches to understand how information is processed in the brain, with the goal of exploiting these findings to improve the human condition. Ongoing and future research questions include the following: Why is coherent electrical activity of the cortex necessary for mental processes like learning and memory? What factors control this […]
Benjamin Wolozin
The goal of our research is to understand the mechanisms underlying neurodegenerative diseases, and then to use this understanding to develop novel interventions for disease. Much of our research focuses on the central concept of regulated protein aggregation. Protein aggregation in neurodegenerative diseases is classically thought to occur as an unwanted byproduct of protein misfolding. […]
Meg Younger
Meg earned a BS in neural science with honors in 2004 from New York University. As an undergraduate, she worked with Justin Blau at NYU on circadian rhythms in Drosophila and with David Spray at Albert Einstein College of Medicine on mammalian gap junction channels. She went on to earn a PhD in neuroscience from […]
Venetia Zachariou
Our research focuses on signal transduction and epigenetic mechanisms underlying CNS disorders and their treatment. We use advanced genetic mouse models, viral mediated gene transfer and multidisciplinary approaches to understand the network and cell type-specific mechanisms of chronic pain, addiction, stress, and depression. Current projects investigate the mechanism by which signal transduction complexes modulate drug […]
Ella Zeldich
Our lab is focusing on studying the cellular and molecular machinery mediating the connection between Down Syndrome and Alzheimer’s disease. We are utilizing 2D and 3D cellular models derived from human induced pluripotent stem (iPS) cells to investigate molecular mechanisms leading to neurodegeneration and demyelination in Alzheimer’s disease, ischemic stroke, and aging. Using iPS cells, […]