29 result(s) found.

• 

  Michael Alosco

  Associate Professor Neurology

  Dr. Alosco completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus in neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. In 2015, Dr. Alosco was awarded a post-doctoral fellowship at the Boston University […]
• 

  Rhoda Au

  Professor of Anatomy & Neurobiology

  Rhoda Au is a Professor of Anatomy & Neurobiology, Neurology, and Epidemiology at Boston University Schools of Medicine and Public. She serves as one of the PIs of the Framingham Heart Study - Brain Aging Program and is also the Director of Neuropsychology. She is also Director of Global Cohort Development for the Davos Alzheimer’s […]
• 

  Helen Barbas

  Professor, Health Sciences

  Our research centers on the organization of the prefrontal cortex and its role in central executive functions in primates. The goal is to investigate prefrontal pathways that interface with both excitatory and inhibitory neurons in cortical and subcortical structures that may provide the basis for the selection of relevant information and suppression of irrelevant information […]
• 

  Lynne Chantranupong

  Assistant Professor of Biology

  Neurons are extremely specialized cells. They can generate intense electrical activity, maintain highly complex morphologies, and survive our entire lifetimes. Moreover, neurons are incredibly diverse, exhibiting a wide range of activity states, shapes, and sizes. These specializations confer different needs and liabilities to neurons, which they must address by adapting their molecular pathways to maintain […]
• 

  Brian DePasquale

  Assistant Professor, Biomedical Engineering

  The DePasquale lab develops mathematical models to understand how populations of neurons perform computations to produce behavior. Broadly, we take two approaches. One is data-driven: we collaborate with experimental neuroscientists to develop tailored machine learning models of neural activity to identify the algorithms that drive behaviors such as decision-making or movement. Our second approach is […]
• 

  David Farb

  Professor and Chair, Pharmacology & Experimental Therapeutics

  As head of the Laboratory of Molecular Neurobiology, Prof. Farb focuses on the identification of pharmacological treatments for disorders of learning and memory function. His research integrates existing electrophysiological, behavioral, pharmacological, and molecular genetic technologies in a novel systems-level platform for assessing the impact of cognitive enhancers such as neuroactive steroids upon fundamental hippocampal systems […]
• 

  Jeffrey Gavornik

  Assistant Professor, Biology

  The basis of all cognitive function is communication between neurons in the brain. This communication is mediated by synaptic connections that are modified by experience to encode function. In order to get at the big question of “how the brain works,” I study how experience-driven synaptic plasticity changes local neocortical physiology. I am particularly interested […]
• 

  Xue Han

  Professor, Biomedical Engineering

  Brain disorders represent the biggest unmet medical need, with many disorders being untreatable, and most treatments presenting serious side effects. Accordingly, we are discovering design principles for novel neuromodulation therapies. We invent and apply a variety of genetic, molecular, pharmacological, optical, and electrical tools to correct neural circuits that go awry within the brain. As […]
• 

  Michael Hasselmo

  Professor, Psychological & Brain Sciences Director, Center for Systems Neuroscience

  Research in the Hasselmo Laboratory concerns the cortical dynamics of memory-guided behavior, including effects of neuromodulation and theta rhythm oscillations in cortical function. Neurophysiological techniques are used to analyze intrinsic and synaptic properties of cortical circuits in rodents and to explore the effects of modulators on these properties. Computational modeling is used to link these […]
• 

  Marc Howard

  Professor, Psychological & Brain Sciences

  We develop mathematical models of cognition and evaluate them against both behavioral and neurophysiological data, providing a bridge between cognition and systems-level neuroscience. We use a combination of mathematical, computational and behavioral tools to evaluate our hypotheses. The topics we investigate are centered on episodic memory, the ability we have to remember specific events situated […]
• 

  Melissa Kibbe

  Associate Professor, Psychological & Brain Sciences

  Prof. Kibbe's research focuses on how infants, children, and adults represent information about objects (e.g. perceptual features, animacy, group statistics, numerosity, verbal labels).  Prof. Kibbe's lab also looks at the kinds of computations we can do with these representations, the ways in which we use these representations to guide behavior, and how cognitive systems (such […]
• 

  Nancy Kopell

  Professor, Mathematics & Statistics

  For the last two decades, Prof. Kopell has worked on mathematical problems in neuroscience. Her current interests parallel the themes of the Cognitive Rhythms Collaborative: how does the brain produce its dynamics (physiological mechanisms), how do brain rhythms take part in cognition (sensory processing, attention, memory, motor control), and how can pathologies of brain dynamics […]
• 

  Jennifer Luebke

  Professor, Anatomy & Neurobiology

  Prof. Luebke maintains a laboratory in which whole-cell patch-clamp and intracellular filling techniques are used to examine the electrophysiological and morphological properties of neurons in in vitro slices of monkey and transgenic mouse neocortex. Research is focused on action potential firing patterns (and underlying ionic currents), glutamatergic and GABAergic synaptic response properties and detailed dendritic […]
• 

  Heng-Ye Man

  Professor of Biology

  Our research interests are focused on brain development, especially neuronal migration, morphogenesis, synapse formation, glutamate receptors and synaptic plasticity. We aim to understand the cellular and molecular processes implicated in neurodegenerative diseases and developmental disorders including autism, Angelman syndrome, intellectual disability and Alzheimer’s disease. We use diverse techniques including biochemistry, immunofluorescent staining, live imaging, virus […]
• 

  Maria Medalla

  Associate Professor, Anatomy & Neurobiology

  Prof. Medalla received her Ph.D. in Applied Anatomy and Physiology at the Boston University Department of Health Sciences in 2008, working with Prof. Helen Barbas to study the structure of ‘cognitive control’ pathways in the prefrontal cortex (PFC) of non-human primates. Her studies in this lab were the first to utilize triple-labeling methods for electron […]
• 

  Heidi Meyer

  Assistant Professor, Psychological & Brain Sciences

  Our approach leverages behavioral, systems, and molecular neuroscience techniques to examine the cognitive and neurodevelopmental underpinnings of affective regulation. Our mission is to take a multi-level approach to neuroscience, setting a solid foundation in learning theory and behavioral assays upon which to apply ever-advancing neuroscience techniques to address a critical gap in knowledge regarding the […]
• 

  Tara Moore

  Associate Professor, Anatomy & Neurobiology

  Prof. Moore received her B.A. in psychology from the University of Calgary and her doctorate in Anatomy and Neurobiology from this department in 2000. She is currently a co-investigator in the Laboratory of Cognitive Neurobiology with Profs. Rosene and Mortazavi. This laboratory investigates the effects of aging and age-related disease on the structure and function […]
• 

  Mark Moss

  Professor Emeritus, Anatomy & Neurobiology

  Together with Prof. Douglas Rosene, Prof. Moss is co-director for the Laboratory for Cognitive Neurobiology. His studies focus on the neurobiology of learning and memory in non-human primate models, particularly with respect to aging and age-related disease. Specific interests include (1) the interaction of the prefrontal cortices with the medial temporal lobe limbic system in […]
• 

  Gabriel Ocker

  Assistant Professor, Mathematics & Statistics

  I work in theoretical neuroscience, studying structure-function relations in neuronal network models. How does neural activity encode sensory information and drive behavior? How do neural circuits evolve, learn, and adapt to shape that activity? How does that connectivity shape activity, and what computations does that activity perform? My group studies models of neural circuits, often […]
• 

  Steve Ramirez

  Associate Professor, Psychological & Brain Sciences

  The mission of my lab is twofold: to reveal the neural circuit mechanisms of memory storage and retrieval, and to artificially modulate memories to combat maladaptive states. We will do so in a multi-disciplinary fashion by combining virus engineering strategies, immunohistochemistry and physiology, optogenetics and functional imaging of targeted populations in vivo, and a battery […]
• 

  Douglas Rosene

  Professor, Anatomy & Neurobiology

  Prof. Rosene is recognized as one of the world’s experts on the anatomy of the temporal lobe limbic system and has published extensively in this area. He is also recognized for his work in the neurobiology of cognitive aging and was Program Director for 15 years of a long-standing NIH Program Project studying the neural […]
• 

  Jean-Pierre Roussarie

  Assistant Professor, Anatomy & Neurobiology

  The Roussarie lab is interested in deciphering the molecular events leading to neurodegeneration in Alzheimer’s disease. Like most neurodegenerative diseases, Alzheimer’s affects only very specific sets of neurons in its earliest stages. These neurons are located in the entorhinal cortex, a brain region indispensable for new memory formation. Dr. Roussarie thinks that understanding the particularities […]
• 

  Karin Schon

  Assistant Professor, Anatomy & Neurobiology

  Prof. Schon’s research interests currently focus on investigating the role of aerobic exercise as a modulator of cognitive function and brain health in aging and Alzheimer’s disease in humans. She uses functional and structural MRI, behavioral and exercise physiology methods, and biomarker assays. Additional research topics include: Cognitive neuroimaging of human memory, brain plasticity, medial […]
• 

  Matthias Stangl

  Assistant Professor, Biomedical Engineering

  Research in my lab focuses on how the human brain supports critical cognitive and behavioral functions in our everyday life, such as spatial navigation and memory, and on the neural mechanisms that underlie age-related impairments in these functions. From a methodological perspective, we employ novel neurotechnologies and advanced methodologies such as deep brain recordings in […]
• 

  Emily Stephen

  Assistant Professor, Mathematics & Statistics

  As a member of the Department of Mathematics and Statistics, I work on statistical modeling and analysis of neural recordings across spatial scales. Propagation of electrical and magnetic fields in the brain depends on both static anatomical features and state-dependent dynamical features like coherence, neuromodulation, and active pathways. My work involves constructing models that use […]
• 

  Robert Stern

  Professor of Neurology, Neurosurgery, and Anatomy & Neurobiology

  A major focus of Prof. Robert Stern's research involves the long-term effects of repetitive brain trauma in athletes, including the neurodegenerative disease, CTE.  He has funding from NIH and the Department of Defense for his work on developing methods of detecting and diagnosing CTE during life, as well as examining potential genetic and other risk […]
• 

  Tuan Leng Tay

  Assistant Professor, Biology

  How do the different types of glial cells, such as astrocytes and microglia, support the healthy development of the brain? They are important in the maintenance and (immune) protection of our nervous system. In disease and injury, glial cells alter themselves in response to a disrupted steady state, potentially to restore health to their neuronal […]
• 

  Julia TCW

  Assistant Professor, Pharmacology & Experimental Therapeutics

  Prof. TCW is interested in understanding Alzheimer’s disease. Her research is focused on a mutant form of Apolipoprotein E (APOE), a major genetic risk factor for Alzheimer’s disease. These studies will provide an opportunity to evaluate the APOE genetic contribution to neurodegeneration associated with the disease by using brain cells derived from human induced pluripotent […]
• 

  Benjamin Wolozin

  Professor, Pharmacology & Neurology

  The goal of our research is to understand the mechanisms underlying neurodegenerative diseases, and then to use this understanding to develop novel interventions for disease. Much of our research focuses on the central concept of regulated protein aggregation. Protein aggregation in neurodegenerative diseases is classically thought to occur as an unwanted byproduct of protein misfolding. […]