David Farb
As head of the Laboratory of Molecular Neurobiology, Prof. Farb focuses on the identification of pharmacological treatments for disorders of learning and memory function. His research integrates existing electrophysiological, behavioral, pharmacological, and molecular genetic technologies in a novel systems-level platform for assessing the impact of cognitive enhancers such as neuroactive steroids upon fundamental hippocampal systems […]
Christopher Gabel
Prof. Gabel’s research program is focused on the development and application of femtosecond laser surgery and optical neurophysiology to the study of the nervous system of the nematode worm C. elegans. Using tightly focused pulses from an ultrafast laser, we can ablate regions of biological tissue with submicron precision, making it possible to snip individual […]
Philipp Mews
The Mews Lab is pioneering research at the intersection of neuroepigenetics, metabolism, and neural plasticity in the adult brain, with an emphasis on substance use disorders. Our research builds on the concept that metabolic processes and the epigenome are deeply interconnected, influencing gene expression and behavior in profound ways. At the heart of our work […]
Shelley Russek
The Russek Laboratory’s chief interests surround a desire to understand how the dynamic regulation of neurotransmitter receptors in the brain shapes the development of the nervous system and how the re-establishment of developmental processes in the adult brain can precipitate neurologic and neuropsychiatric diseases. The identification of gene families with multiple genes that code for […]
Valentina Sabino
Prof. Sabino is co-director of the Laboratory of Addictive Disorders, and is currently researching the neurobiology of addiction and stress-related disorders and studies on addiction, aiming to understand the neurobiological substrates of alcohol abuse and dependence by exploring the role of neurochemical systems in excessive alcohol drinking. Prof. Sabino is working toward the development of […]
Matthias Stangl
Research in my lab focuses on how the human brain supports critical cognitive and behavioral functions in our everyday life, such as spatial navigation and memory, and on the neural mechanisms that underlie age-related impairments in these functions. From a methodological perspective, we employ novel neurotechnologies and advanced methodologies such as deep brain recordings in […]
Julia TCW
Prof. TCW is interested in understanding Alzheimer’s disease. Her research is focused on a mutant form of Apolipoprotein E (APOE), a major genetic risk factor for Alzheimer’s disease. These studies will provide an opportunity to evaluate the APOE genetic contribution to neurodegeneration associated with the disease by using brain cells derived from human induced pluripotent […]
Benjamin Wolozin
The goal of our research is to understand the mechanisms underlying neurodegenerative diseases, and then to use this understanding to develop novel interventions for disease. Much of our research focuses on the central concept of regulated protein aggregation. Protein aggregation in neurodegenerative diseases is classically thought to occur as an unwanted byproduct of protein misfolding. […]