David Boas
The Boas Lab develops novel optical methods and applies them principally to study the brain. We have recently expanded to complement our suite of technologies with high-speed functional ultrasound and are considering integration with photo-acoustics. Our technologies are used for measuring brain function and physiology on microscopic to macroscopic length scales and are applied in […]
H. Steven Colburn
Prof. Colburn’s research involves the application of signal processing, statistical communication theory, and computational modeling to the study of hearing and hearing impairments. Prof. Colburn is particularly interested in the measurement and modeling of binaural hearing performance. Specific current topics include modeling the activity of auditory brainstem neurons and measurement and modeling of spatial attributes […]
Brian DePasquale
The DePasquale lab develops mathematical models to understand how populations of neurons perform computations to produce behavior. Broadly, we take two approaches. One is data-driven: we collaborate with experimental neuroscientists to develop tailored machine learning models of neural activity to identify the algorithms that drive behaviors such as decision-making or movement. Our second approach is […]
Anna Devor
We are an imaging lab. We specialize in imaging neuronal, glial, vascular, and metabolic activity in brains of living and behaving experimental animals. We also use stem-cell-derived human neuronal networks. We focus on obtaining high resolution, sensitivity and specificity optical measurements and combine optical imaging with electrophysiological recordings and functional Magnetic Resonance Imaging (fMRI). Our […]
Michael Economo
Prof. Economo’s laboratory studies the structure and function of the neural circuits distributed across the brain that control movement. His research leverages cutting edge optical, electrophysiological, and genetic tools for recording and manipulating neural activity during behavior and for illuminating the structure of neural circuits.
Oded Ghitza
Decoding speech using neuronal oscillations; Hierarchical neuronal oscillators and the basis for cortical computation; Analysis of MEG signals recorded while performing a speech perception task; Predicting consonant confusions in noise; Closed‐loop auditory models for robust automatic speech recognition; Modeling damaged cochleae using speech‐governed methodologies. Prof. Ghitza’s current research focuses on the formulation of cortical computation […]
Xue Han
Brain disorders represent the biggest unmet medical need, with many disorders being untreatable, and most treatments presenting serious side effects. Accordingly, we are discovering design principles for novel neuromodulation therapies. We invent and apply a variety of genetic, molecular, pharmacological, optical, and electrical tools to correct neural circuits that go awry within the brain. As […]
Jerome Mertz
Prof. Mertz’s lab focuses on the development and applications of novel optical microscopy techniques for biomedical imaging. Some specific topics include imaging through complex media, imaging through a single optical fiber, and oblique back-illumination microscopy.
Tim O’Shea
The central premise of our research is that we can improve treatments for various brain and spinal cord disorders by developing new bioengineered strategies that can favorably regulate glial cell functions. Across all projects we aim to achieve two key outcomes: (i) Contribute to furthering fundamental glia biology knowledge, and (ii) Developing new bioengineering solutions […]
Kamal Sen
How do neurons in the brain encode complex natural sounds? What are the neural substrates of selectivity for and discrimination of different categories of natural sounds? Are these substrates innate or shaped by learning? Our laboratory investigates these questions with a focus on auditory cortex. Electrophysiological techniques are used to record neural responses from hierarchical […]