News about research publications
Insights into Protein-Misfolding Diseases
The work of Professor John Straub and his collaborator at the University of Maryland, Professor Dave Thirumalai, demonstrates that when aggregation occurs in aqueous solution between amyloid or prion peptides …
Wang Research Featured in Journal of Chemical Physics and Honored at the ACS National Meeting
The cover of the Aug. 28th, 2010 issue of the Journal of Chemical Physics, highlights a free-energy diagram calculated with a new enhanced sampling method developed by Professor Feng Wang and his Group (J. Chem. Phys. 113, 084101 {2010]). Their method mimics features of a coarse-grained simulation at the atomic scale. Recent validations performed by […]
Karen Allen research reported in Nature
Karen Allen research reported in Nature solves how the enzyme acetoacetate decarboxylase (AADase) works in cell environment Professor Karen Allen, an internationally renown crystallographer in the Department of Chemistry and her colleagues, BU graduate student Meng-Chiao Ho and post-doctoral associate Jean-Francois Menetret, and Hiro Tsuruta of the Stanford Synchrotron Radiation Lightsource of the National Accelerator […]
TULLIUS Group results published in Science
TULLIUS Group reports in Science that evolutionary selection works on DNA shape Professor Tom Tullius, his graduate student, Steve Parker, and their collaborator at the National Institutes of Health, Dr. Elliott Margulies, have developed a new methodfor uncovering functional areas of the human genome by studying DNA’s three-dimensional structure — a topographical approach that extends […]
Schaus Group Develops New Asymmetric Route To α-Amino Acid Esters
Chemical & Engineering News: Science & Technology (5/19/08) reports in a “Highlight” that Sha Lou and Scott E. Schaus have developed the first asymmetric catalytic version of the reaction. It uses chiral biphenol catalysts to convert alkenyl boronates, secondary amines, and glyoxylates to chiral α-amino acid esters with good yields and high enantiomeric ratios (J. […]
New Catalytic Method Discovered by Schaus and CMLD-BU featured in C&E News
From Chemical & Engineering News (Vol 83, p. 13): The asymmetric construction of monastrol and other dihydropyrimidones has been a challenge for some time. The compounds are generally produced as racemates by the Biginelli reaction, developed in 1893, and single enantiomers are obtained by chiral resolution. Assistant professor of chemistry Scott E. Schaus and coworkers […]