NF-kB Inducers

Inducers of NF-kB Activity

Bacteria and Fungi

Bacterial or Fungal Products


Viral Products

Eukaryotic parasite

(Inflammatory) Cytokines

Physiological (Stress) Conditions

Physical Stress

Oxidative Stress

Environmental Hazards

Therapeutically used drugs

Modified Proteins

Overexpressed Proteins (ER Overload sometimes)

Receptor Ligands

Apoptotic Mediators

Mitogens, Growth Factors and Hormones

Physiological Mediators

Chemical Agents

In addition to the list above, Matsuda et al (2003) have identified 83 cDNAs that can induce NF-kB reporter gene activity upon transfection.  (Matsuda et al, 2003, Large-scale identification and characterization of human genes that activate NF-kB and MAPK signaling pathways. Oncogene 22 3307-3318)