PhD in Bioinformatics

The PhD in Bioinformatics program offers unique interdisciplinary training for graduate students in the science, engineering, medicine, and ethics of twenty-first-century cell biology jointly through the College of Engineering and the Graduate School of Arts & Sciences. The program aims to prepare top researchers for careers in both academia and industry in the areas of molecular life sciences. In order to be admitted, students need at least a bachelor’s degree in a field related to bioinformatics, preferably one with a strong component in mathematics and computer science.

Course Requirements

Post-Bachelor’s Requirements

The post-bachelor’s PhD requires a total of 64 course credits, consisting of the 40 required credits listed below, or their equivalents, and additional elective lecture, laboratory, and research credits. The precise course of study will be determined in consultation with faculty advisors and will reflect the student’s background and interests. In order to be admitted to PhD candidacy, students must demonstrate mastery of the required subject matter (no lower than a B in each of the required courses). Course requirements are as follows:

  • ENG BE 562: Computational Biology: Genomes, Networks, Evolution
  • ENG BF 768: Biological Database Systems
  • ENG BE 777: Computational Genomics I
  • ENG BF 690: Bioinformatics Challenge Project (2 cr each; 4 total)
  • ENG BF 751: Molecular Biology and Biochemistry: Molecules and Processes
  • ENG BF 752: Legal and Ethical Issues of Science and Technology
  • ENG BF 778: Physical Chemistry for Systems Biology
  • ENG BF 810: Laboratory Rotation System
  • ENG BF 820: Research Opportunities in Bioinformatics
  • ENG BF 821: Bioinformatics Graduate Seminar (2 cr each; 4 total)
  • GRS MA 681: Accelerated Introduction to Statistical Methods for Quantitative Research
  • One non-research elective course
  • A minimum of 2 research credits

Fulfillment of required course equivalents will be determined based on documented previous academic and/or work experience. The student and his or her advisors will petition the curriculum committee for such equivalencies. When either past work or an alternate course has been accepted as a required course equivalent, the student’s advisors will recommend another course to fulfill the 40 core credit hours. Advanced elective courses should be taken in place of any waived course requirements.

Post-Master’s Requirements

The post-master’s PhD requires 40 credits of coursework, consisting of an appropriate combination of lecture, laboratory, and research, as recommended by the student’s thesis advisor. Other requirements are the same as for the post-bachelor’s PhD, except post-master’s students are not required to take one non-research elective course.

Qualifying Examination

Students must pass an oral qualifying exam in order to advance to the level of PhD candidacy. The goal of the exam is for the student to demonstrate his or her general proficiency in bioinformatics, as well as command of the area(s) in which he or she intends to conduct research. All parts of the qualifying examination must be passed before the dissertation or thesis prospectus will be accepted by the Graduate School of Arts & Sciences.

Students must schedule their qualifying exam by March 31 of their second year, and must take the exam by June 30. Students who fail to pass the exam on their first try are allowed a second attempt, to be scheduled and completed by the end of the first semester of their third year.

Language Requirement

There is no foreign language requirement for the bioinformatics degree. However, basic mastery of spoken and written English, as determined by oral presentations, written reports, and publishable manuscripts, is a requirement for the PhD.

Dissertation and Final Oral Examination

Candidates shall demonstrate their abilities for independent study in a dissertation representing original research or creative scholarship. A prospectus for the dissertation must be completed and approved by the readers, the director of graduate studies, and the department chair/program director. Candidates must undergo a final oral examination in which they defend their dissertations as a valuable contribution to knowledge in their field and demonstrate a mastery of their field of specialization in relation to their dissertation. All portions of the dissertation and final oral examination must be completed as outlined in the GRS General Requirements for the Doctor of Philosophy Degree.